Embryonic Development News and Research

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Embryonic development or embryogenesis is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum, egg, which, after fertilization, is then called a zygote. The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo.

Scientists gain greater understanding of how embryos differentiate left from right

Researchers at the Forsyth Institute have discovered a new mechanism responsible for early left/right patterning, the process by which organs locate themselves on the left or right side of the body.

19 Apr 2006

Active ingredient in soy may explain why Asians have lower rates of obesity and cancer

A single nutrient found in soy products elicits changes in gene behavior that permanently reduce an embryo's risk of becoming obese later in life, according to an animal study at Duke University Medical Center.

13 Apr 2006

Research explains why recipients of growth hormone therapy may develop colon polyps

The use of growth hormone therapy has been linked in some people to the development of colon polyps, a possible precursor to colorectal cancer - but medical researchers have debated the extent of a cancer risk.

11 Apr 2006

Losartan can prevent progression of Marfan syndrome

A commonly prescribed blood pressure medication may provide the first ray of hope in preventing potentially deadly complications of Marfan syndrome, a genetic disease that weakens the structural meshwork of blood vessels.

11 Apr 2006

Protein loss linked to colon polyp risk from growth hormone

10 Apr 2006

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

The unchecked activity of a cell signaling pathway crucial in embryonic development and the liver's response to injury leads to liver cancer, researchers from Duke University Medical Center and John Hopkins University School of Medicine have found.

4 Apr 2006

Scientists reprogramme malignant melanoma cells to become normal pigment cells

Scientists at Northwestern University and the Stowers Institute for Medical Research have reprogrammed malignant melanoma cells to become normal melanocytes, or pigment cells, a development that may hold promise in treating of one of the deadliest forms of cancer.

1 Mar 2006

Study provides further insight into the molecular control of apoptosis

Researchers at Yale School of Medicine have gained deeper understanding of two members of a family of proteins called caspases that play a key role in promoting apoptosis, a process in which the cell responds to external signals by essentially committing suicide.

23 Feb 2006

Cell growth and cell division genes identified

A recent study shows that hundreds of genes contribute to cell growth and cell division. For the first time these genes, many of which are potential contributors to cancer, have been mapped in a single systematic study.

23 Feb 2006

Cancer researchers find evolutionary change that occurred in a key developmental signalling pathway

Cancer researchers at the University of Helsinki, in trying to find a novel tumor suppressor gene, instead found an important evolutionary change that occurred in a key developmental signalling pathway. The finding suggests a potential mechanism for evolution of complex intercellular signalling pathways.

9 Feb 2006

Researchers find new mechanism potentially explaining evolution of signalling pathways

7 Feb 2006

Histidine may be key to new therapies for cardiovascular disease

It's just one little amino acid, but it makes all the difference in protecting the heart from the harmful effects of heart attack and cardiac failure. Researchers from the University of Michigan Medical School suggest this amino acid, called histidine, could be the key to a new therapy for cardiovascular disease

23 Jan 2006

Cloned stem cells are perfectly normal

Scientists generally agree that all cloned animals are biologically flawed. But they don't agree about what that means for stem cells derived from cloned embryos, the basis for therapeutic cloning.

18 Jan 2006

Remarkable developmental pathway in frog embryos discovered

Howard Hughes Medical Institute researchers have discovered an important regulatory pathway that enables frog embryos to develop normally even after being split in half -- as happens in the development of identical twins.

15 Dec 2005

Dog gene map may help explain human diseases

U.S. scientists say a detailed analysis of the dog genome answers such questions as how dogs of a different breed still belong to the same species, and may also explain some aspects of human health and biology.

11 Dec 2005

Transport mechanisms for serotonin

Researchers at The Forsyth Institute have discovered that the transport mechanisms for serotonin - the chemical substance involved in transmitting signals between neurons, and which has a role in anxiety and mood disorders - play a key role in determining where organs are positioned in the body during embryonic development.

7 Dec 2005

Researchers link microRNA - miR 196 - to limb development

A tiny strand of molecules plays a role in how our arms and legs develop and grow - a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University.

5 Dec 2005

Exploiting biology's own chemical toolbox...

Exploiting biology's own chemical toolbox, researchers have developed a new technique that will allow them to modify specific sequences within a DNA molecule. The approach will not only help reveal the impact of biochemical alterations to DNA, but could have far-reaching implications for DNA-based medical diagnosis and nanobiotechnology.

28 Nov 2005

Scientists find key step in a signaling pathway that helps orchestrate embryonic development

The study, reported in Nature (Oct. 13, 2005), focuses on the Hedgehog family of signaling molecules, which play a central role in directing development of the early embryo's growth and spatial plan, as well as its later organ and limb development. Defects in Hedgehog signaling are a significant cause of some birth defects and cancers.

25 Oct 2005

How cells use very slow biological flows to signal and organize

An EPFL (Ecole Polytechnique Federale de Lausanne) team led by professor Melody Swartz has demonstrated for the first time that the presence of very slow biological flows affects the extracellular environment in ways that are critical for tissue formation and cell migration.

25 Oct 2005