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New finding on key protein opens door to potential therapies for chronic illnesses

Scientists have determined unexpected characteristics of a key protein linked to blood pressure control and to nerve growth, pain control and heart tissue regeneration. The findings, published April 5 online in the journal Nature, opens doors to potential new therapies to control cardiovascular disease and pain.

6 Apr 2017

Study shows how chemical modification in the retinal can improve vision

A light-sensing pigment found in everything from bacteria to vertebrates can be biochemically manipulated to reset itself, an important therapeutic advantage, according to new research out of Case Western Reserve University School of Medicine.

6 Apr 2017

X-ray study sheds new light on promising drug target

Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins adorning cell surfaces, which are the targets of the majority of pharmaceutical drugs.

5 Apr 2017

Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets.

5 Apr 2017

Researchers achieve new step towards treatment of myotubular myopathy using gene therapy

A team of researchers in France, led by Dr. Ana Buj-Bello (Genethon/Inserm) and teams at the University of Washington and Harvard Medical School in the United States, achieved a new step towards the treatment of myotubular myopathy by gene therapy.

5 Apr 2017

Protein testing may become potential tool to detect prostate cancer

In 2016, more than 181,000 new cases of prostate cancer were reported in the U.S., according to the American Cancer Society. The prostate-specific antigen (PSA) test is one of the earliest ways clinicians can detect prostate cancers in their patients.

5 Apr 2017

Newly-discovered mechanism for compound may help prevent neurologic damage

Researchers at Oregon State University have found that a compound called rapamycin has unusual properties that may help address neurologic damage such as Alzheimer's disease.

5 Apr 2017

OIST scientists use zebrafish model to unravel causes behind human LCA

Newborns babies can be at risk of congenital blindness, presenting sight defects due to lesions or to genetic mutations in their genome.

5 Apr 2017

Dose sparing could increase vaccine availability without compromising safety

The currently licensed seasonal trivalent influenza vaccines contain 15 micrograms of viral hemagglutinin protein per strain for adults, and up to 60 micrograms for elderly individuals; however, due to recent shortages, reducing these doses would be highly desirable.

5 Apr 2017

Tumor microenvironment poses unique challenges for effective ovarian cancer T-cell therapy

Fred Hutchinson Cancer Research Center immunotherapy researchers Drs. Kristin Anderson and Philip Greenberg and their colleagues are working on ways to tweak their team's early successes with T-cell therapy for leukemia to apply to solid tumors.

5 Apr 2017

BioDirection's TBI detection system shows potential to reduce unnecessary CT scans

BioDirection, Inc., a privately held medical device company developing novel and rapid point-of-care products for the objective detection of concussion and other traumatic brain injury (TBI), announced today results from a pre-clinical study show that the company’s Tbit™ System for the detection of TBI is sensitive, provides actionable results in point-of-care settings, and has the potential to reduce the number of unnecessary computerized tomography (CT) scans.

5 Apr 2017

Zika virus may pose increased risk to people previously infected with dengue and West Nile, study finds

As the Zika virus continues to spread rapidly across the globe, it might pose a particular risk to people previously infected with two related viruses, dengue and West Nile, researchers at the Icahn School of Medicine at Mount Sinai have found.

5 Apr 2017

Supercomputers reveal how cell membranes control shape and function of cancer-causing protein

Two biophysicists from Case Western Reserve University School of Medicine have used supercomputers to show how cell membranes control the shape, and consequently the function, of a major cancer-causing protein.

4 Apr 2017

Scientists find new drug target to improve cardiac output in heart failure patients

Researchers led by Julian E. Stelzer, PhD, associate professor in the department of physiology and biophysics at Case Western Reserve University School of Medicine, have found a new target for drug developers seeking straightforward ways to improve cardiac output in heart failure patients.

4 Apr 2017

Simple marker may help predict high or low rate of problems with extended-wear contact lenses

A simple marker on eye examination may help vision care professionals predict which patients will have a higher or lower rate of problems after starting extended-wear contact lenses, reports a study in the April issue of Optometry and Vision Science, the official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.

4 Apr 2017

Researchers identify mechanism to recover aging of Progeria patients

DGIST's research team has identified a mechanism that can recover the aging of patients with Hutchinson-Gilford Progeria Syndrome. DGIST announced that the Chair Professor Park SangChul of New Biology and the research team led by Professor Lee YoungSam has discovered a drug that can improve the aging of HGPS patients and identified the mechanism of aging recovery by using the drug.

4 Apr 2017

Researchers show how cellular stress regulates production of hemoglobin

Our ability to breathe oxygen is critical to our survival. This process is mediated by the hemoglobin in our blood, which carries oxygen. Since air contains less oxygen on high mountains, the body is under pressure to make hemoglobin rapidly -- a stressful time.

4 Apr 2017

Scientists identify new gene that drives drug resistance in breast cancer

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G Protein News and Research

New finding on key protein opens door to potential therapies for chronic illnesses

Study shows how chemical modification in the retinal can improve vision

X-ray study sheds new light on promising drug target

Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

Researchers achieve new step towards treatment of myotubular myopathy using gene therapy

Protein testing may become potential tool to detect prostate cancer

Newly-discovered mechanism for compound may help prevent neurologic damage

OIST scientists use zebrafish model to unravel causes behind human LCA

Dose sparing could increase vaccine availability without compromising safety

Tumor microenvironment poses unique challenges for effective ovarian cancer T-cell therapy

BioDirection's TBI detection system shows potential to reduce unnecessary CT scans

Zika virus may pose increased risk to people previously infected with dengue and West Nile, study finds

Supercomputers reveal how cell membranes control shape and function of cancer-causing protein

Scientists find new drug target to improve cardiac output in heart failure patients

Simple marker may help predict high or low rate of problems with extended-wear contact lenses

Researchers identify mechanism to recover aging of Progeria patients

Researchers show how cellular stress regulates production of hemoglobin

Scientists identify new gene that drives drug resistance in breast cancer

Pitt scientists identify neural pathway that regulates coordinated hand movements

Attacking TERT protein may be effective approach to destroying ALM cancer cells

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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