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Pesticides, other environmental pollutants advance progression of ALS

While exact causes of amyotrophic lateral sclerosis (ALS) remain unknown, new research shows pesticides and other environmental pollutants advance the progression of the neurodegenerative disease.

28 Feb 2019

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change¾one in a gene involved in muscle formation¾in five of the tumors.

28 Feb 2019

Experimental treatment offers hope to restore cells damaged in Parkinson's disease

A pioneering clinical trials program that delivered an experimental treatment directly to the brain offers hope that it may be possible to restore the cells damaged in Parkinson's disease.

27 Feb 2019

Pioneering trial offers hope for patients with Parkinson’s disease

In a pioneering new clinical trial, researchers have succeeded in delivering a cell-restoring drug directly to the brains of patients with Parkinson’s disease.

27 Feb 2019

Pioneering clinical trials offers hope to restore damaged cells in Parkinson's disease

The three-part multimillion-pound GDNF study was funded by Parkinson's UK with support from The Cure Parkinson's Trust and in association with the North Bristol NHS Trust.

26 Feb 2019

Scientists discover puzzle piece that plays key role in development of epilepsies

When an epileptic seizure occurs in the brain, the nerve cells lose their usual pattern and fire in a very fast rhythm. The cause is a complex interplay of various factors.

25 Feb 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

Newly released national framework identifies obstacles to improving EMS systems

As part of nationwide efforts to improve emergency medical care, researchers at the Mount Sinai Health System, in collaboration with UC San Diego Health, have released a national framework report titled "Promoting Innovations in Emergency Medical Services" that identifies regulatory, financial, and technological obstacles to improving local and state EMS systems.

20 Feb 2019

Study suggests new treatment strategy for deadly brain cancer

In a study of mice and human brain tumors researchers at the University of the Michigan, Ann Arbor, searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others.

19 Feb 2019

Study finds new link between food allergies and multiple sclerosis

Like many other medical conditions, the mechanism of multiple sclerosis remains an enigma--a puzzle composed of complex genetic and environmental factors. A key piece to this puzzle is the immune system, which is also responsible for regulating many other physiological (and pathological) phenomena--including allergies.

19 Feb 2019

Newly developed stem cell technologies show promise for treating PD patients

Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

15 Feb 2019

New eHealth tool shows potential to improve quality of asthma care

A new electronic decision support tool for managing asthma has the potential to improve the quality of asthma care in primary care settings, suggests a study led by St. Michael's Hospital in Toronto, Canada.

14 Feb 2019

Mount Sinai awarded $12.5 million NIH grant for research program in aging biology

Researchers from the Icahn School of Medicine at Mount Sinai have been awarded a $12.5 million grant from the National Institute on Aging, part of the National Institutes of Health, for a five-year program called the U19 that consists of four multidisciplinary projects in aging biology.

14 Feb 2019

Prior dengue virus infection increases Zika virus-induced damage during pregnancy

Women who have previously been infected with dengue virus may be at risk for increased damage to their fetuses and placentas if they should later become infected with the Zika virus, researchers from the Department of Microbiology at the Icahn School of Medicine at Mount Sinai report.

11 Feb 2019

Removing 70% or more of the brain hemorrhage could produce better outcomes, study finds

In the first study to identify specific surgical goals for the treatment of an intracerebral hemorrhage--the deadliest and most disabling type of stroke--a team of neurosurgeons found that at least 70 percent of the hemorrhage has to be removed for patients to make a meaningful recovery.

8 Feb 2019

New prostate cancer prediction tool has unmatched accuracy

A team of researchers from the Icahn School of Medicine at Mount Sinai and Keck School of Medicine at the University of Southern California have developed a novel machine-learning framework that distinguishes between low- and high-risk prostate cancer with more precision than ever before.

7 Feb 2019

Spinal cord stimulation can restore voluntary movement and autonomic functions in paralyzed patients

There are more than 290,000 people estimated to be living in the United States with a spinal cord injury. Previously, it has been shown that it is possible to restore some function to young and healthy patients within a few years of injury.

1 Feb 2019

New research shows adult neurogenesis does not persist in the human hippocampus

The generation of new neurons in the human hippocampus strongly decreases from childhood to almost undetectable levels in adults. It can therefore be stated that neurogenesis in the human hippocampus is almost non-existent, as opposed to what has been thought in recent decades.

29 Jan 2019

Researchers discover immune regulator that appears to dictate glioblastoma

Researchers at The University of Texas MD Anderson Cancer Center have discovered an immune regulator that appears to dictate glioblastoma progression by shutting down immune surveillance, indicating a potential new area of therapeutic investigation.

28 Jan 2019