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PCRF awards £1.2M grants for new research projects tackling pancreatic cancer

Seven innovative research projects tackling pancreatic cancer have been awarded grants totalling £1.2M by the UK medical research charity, Pancreatic Cancer Research Fund.

28 May 2019

Epigenetic research provides new approaches to cancer combination therapies

Epigenetic processes enable cells to respond to changes in their environment by regulating the activity of their genes.

28 May 2019

Are DNA-based diets and personalized 'medical foods' the future for weight loss?

Experts say that by understanding how a person responds to specific nutrients, healthcare practitioners could provide better nutritional advice.

28 May 2019

Mutations within junk DNA linked to autism spectrum disorder

Using artificial intelligence, scientists have discovered mutations in parts of non-coding DNA known as “Junk DNA” that can lead to autism.

28 May 2019

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells.

28 May 2019

Large-scale genomic sequencing narrows search for Strep A vaccine

The global search for a group A streptococcal (Strep A) vaccine has narrowed after researchers identified a common gene signature in almost all global Strep A strains by sequencing thousands of genomes in a project spanning 10 years and more than 20 countries.

28 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Researchers get one step closer to global Strep A vaccine

The search for a global Strep A vaccine has narrowed after researchers sequenced the DNA of more than 2000 Group A Streptococcus samples from around the world.

27 May 2019

Mutations in 'junk' DNA can cause autism, study shows

Leveraging artificial intelligence techniques, researchers have demonstrated that mutations in so-called 'junk' DNA can cause autism.

27 May 2019

Artificial intelligence technique identifies new class of mutations behind autism

Many mutations in DNA that contribute to disease are not in actual genes but instead lie in the 99% of the genome once considered "junk." Even though scientists have recently come to understand that these vast stretches of DNA do in fact play critical roles, deciphering these effects on a wide scale has been impossible until now.

27 May 2019

Novel method for evaluating genomic sequencing results in newborn screening

Newborn screening is required in the U.S. and differs slightly depending on which state you live in. For the most part, it's done before a newborn baby leaves the hospital and includes a blood test that screens for 30-50 serious health problems that usually arise in infancy or childhood, and could hinder normal development.

26 May 2019

Starving the fungus could help fight drug-resistant fungal infections

How do you fight a fungal infection that is becoming increasingly resistant to medicine? By starving it, found a team of University at Buffalo and Temple University researchers.

26 May 2019

Researchers discover new function of ribosomes in human cells

Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle's role in destroying healthy mRNAs, the messages that decode DNA into protein.

26 May 2019

Study clarifies how 3D organization of genome is regulated at onset of skeletal muscle formation

A new study from the University of Minnesota Medical School clarifies how the three-dimensional organization of the genome is regulated at the onset of skeletal muscle formation.

25 May 2019

Infants at high risk for autism are less attuned to differences in speech patterns

A new study by Columbia University researchers found that infants at high risk for autism were less attuned to differences in speech patterns than low-risk infants.

25 May 2019

Newly approved gene therapy for SMA is based on delivery vehicle discovered by Penn expert

James Wilson, MD, PhD, recalls being struck by the devastating toll of rare diseases as a young physician in the 1980s. He set out on a path to correct the genes that cause these conditions, including spinal muscle atrophy (SMA), the most common inherited fatal disease in infants.

25 May 2019

New statement emphasizes need for special multidisciplinary clinical programs

With a better understanding of how various heart conditions are inherited, and the availability of faster and less expensive genetic testing, there is need for more specialized multidisciplinary clinical programs that combine focused expertise in heart disease and genetics, according to a new statement from the American Heart Association, the world's leading voluntary organization focused on heart and brain health.

25 May 2019

LMU microbiologists characterize structure of gastric bacterium population in individual patients

Helicobacter pylori, a globally distributed gastric bacterium, is genetically highly adaptable. Microbiologists at Ludwig-Maximilians-Universitaet in Munich have now characterized its population structure in individual patients, demonstrating an important role of antibiotics for its within-patient evolution.

25 May 2019

Are fruit fly 'avatars' the next step in personalized medicine?

Researchers have created fruit fly “avatars” that have helped to guide treatment for a man who had terminal colon cancer.

24 May 2019

Cell scientist receives $1.9 million NIH grant to study muscle regeneration

As people age, their muscle regeneration capacity declines in part because they can no longer make enough muscle stem cells to replace damaged tissue.

24 May 2019

Genes News and Research

PCRF awards £1.2M grants for new research projects tackling pancreatic cancer

Epigenetic research provides new approaches to cancer combination therapies

Are DNA-based diets and personalized 'medical foods' the future for weight loss?

Mutations within junk DNA linked to autism spectrum disorder

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Large-scale genomic sequencing narrows search for Strep A vaccine

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

Researchers get one step closer to global Strep A vaccine

Mutations in 'junk' DNA can cause autism, study shows

Artificial intelligence technique identifies new class of mutations behind autism

Novel method for evaluating genomic sequencing results in newborn screening

Starving the fungus could help fight drug-resistant fungal infections

Researchers discover new function of ribosomes in human cells

Study clarifies how 3D organization of genome is regulated at onset of skeletal muscle formation

Infants at high risk for autism are less attuned to differences in speech patterns

Newly approved gene therapy for SMA is based on delivery vehicle discovered by Penn expert

New statement emphasizes need for special multidisciplinary clinical programs

LMU microbiologists characterize structure of gastric bacterium population in individual patients

Are fruit fly 'avatars' the next step in personalized medicine?

Cell scientist receives $1.9 million NIH grant to study muscle regeneration

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