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Study sheds new light on impact of COVID-19 in pediatric population

In the most comprehensive analysis to date of U.S. children tested and treated for COVID-19, an organization representing seven of the nation's largest pediatric medical centers reports that some groups of children are faring significantly worse than children in general during the pandemic.

24 Nov 2020

Research provides key information on transmission, development of mutations in SARS-CoV-2 virus

In the COVID-19 pandemic, 57 million people have already been infected worldwide. In the search for vaccines and therapies, a precise understanding of the virus, its mutations, and transmission mechanisms are crucial.

24 Nov 2020

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

Wastewater surveillance has been reported to be a feasible and efficient way to monitor the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the current COVID-19 pandemic. A recent study draws attention to the need to freeze wastewater samples if the analysis is carried out later rather than immediately.

24 Nov 2020

Study: Aprotinin can inhibit virus replication by preventing SARS-CoV2 entry into host cells

The surface of the SARS-CoV-2 virus is studded with spike proteins. The virus needs these in order to dock onto proteins (ACE2 receptors) on the surface of the host cell.

24 Nov 2020

COVID-19: HLA class I genotypes and mortality

The study, published on the preprint server medRxiv, explores the ability of HLA class I molecules to mediate the outcome in COVID-19 patients.

24 Nov 2020

Early high-titer convalescent plasma prevents 75% of severe COVID-19 in elderly

A promising new clinical study published on the preprint server medRxiv reports that if convalescent plasma with a high titer of antibodies is given early in the course of COVID-19 in elderly patients, the risk of severe illness is reduced by 73%.

24 Nov 2020

Researchers develop new search engine to investigate viral sequences in COVID-19

Since the beginning of 2020, labs from all around the world are sequencing the material from positive tests of people affected by COVID-19 and then depositing sequences mostly to three points of collection: GenBank, COG-UK, and GISAID.

23 Nov 2020

Marinomed to initiate clinical trial with Carragelose for preventing COVID19 in frontline healthcare staff

Marinomed Biotech AG, a globally operating biopharmaceutical company, announced today plans to initiate a Phase IV clinical trial with Carragelose (iota-carrageenan).

23 Nov 2020

Favorable clinical outcome for ivermectin in COVID-19 animal model

A team of researchers at the Institut Pasteur in France has found that ivermectin prevented clinical deterioration in infected animals. The drug also reduced the inflammatory cytokines, interleukin-6 and 10 (IL-6 and IL-10) in lung tissue, which leads to more favorable clinical outcomes in treated animals.

23 Nov 2020

Thromboembolism in COVID-19 patients associated with higher risk of mortality

While respiratory issues continue to be the most common symptom of a COVID-19 infection, new research indicates the disease could also be associated with hypercoagulability, or increased tendency of the blood to clot.

23 Nov 2020

Scientists studying aerodynamics of infectious disease reveal ways to reduce indoor SARS-CoV-2 transmission

At the 73rd Annual Meeting of the American Physical Society's Division of the Americal Physical Society's Division of Fluid Dynamics, researchers presented a range of studies investigating the aerodynamics of infectious disease.

23 Nov 2020

Septic shock and pneumonia triggered by SARS-CoV-2 could be treated by radiation-activated MSCs

This study, published in the journal Cells, is based on others (all of which employed experimental models) previously conducted by researchers at the Biomedical Research Centre of the University of Granada, the ‘López-Neyra’ Institute of Parasitology and Biomedicine, and the ‘Virgen de las Nieves’ University Hospital in Granada

23 Nov 2020

Duke-NUS expert joins international taskforce to study the origins of SARS-CoV-2 virus

Nearly a year since the world first learned of the novel coronavirus disease 2019, COVID-19, many questions remain about SARS-CoV-2, the virus behind this pandemic: Where did it come from, how did it spread so widely and rapidly, and how can we stop similar outbreaks in the future?

23 Nov 2020

New CDC report describes COVID-19 in NYC in early spring

The Centres for Disease Control and Prevention (CDC), in its Morbidity and Mortality Weekly Report (MMWR), has published an update on the outbreak in New York City. The report is titled, "COVID-19 Outbreak — New York City, February 29–June 1, 2020".

23 Nov 2020

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

Researchers in Brazil have reported two cases of people with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding infectious virus for a significantly longer period than has previously been reported.

23 Nov 2020

Repeat infection following COVID-19 recovery may not pose risk to close contacts

Researchers in China have conducted a study suggesting that people who have recovered from coronavirus disease 2019 (COVID-19) may not pose a risk to close contacts if they become reinfected with the causative agent severe acute respiratory syndrome coronavirus (SARS-CoV-2).

23 Nov 2020

SARS-CoV-2's spike protein mutations have slowed, study finds

A team of researchers at the School of Information Sciences in Illinois, USA, has revealed the rate of mutation in the 29 proteins that make up the SARS-CoV-2 microbe.

23 Nov 2020

How COVID-19 compares to other respiratory illnesses

A team of scientists from Israel and the United States has compared the disease presentation and progression between in-hospital patients with coronavirus disease 2019 (COVID-19) and other respiratory illnesses such as influenza.

23 Nov 2020

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

A thought-provoking new study reports that the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibodies elicited by natural infection may not be able to neutralize emerging strains that display deletion mutations in their genomic RNA.

23 Nov 2020

Nasal dryness could be an early warning sign of COVID-19

A new study published by an international team of researchers on the preprint medRxiv* server in November 2020 details the nasal symptoms that are associated with anosmia and ageusia (loss of smell and taste) in coronavirus disease 2019 (COVID-19), including the early warning signs of infection.

23 Nov 2020

SARS News and Research

Study sheds new light on impact of COVID-19 in pediatric population

Research provides key information on transmission, development of mutations in SARS-CoV-2 virus

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

Study: Aprotinin can inhibit virus replication by preventing SARS-CoV2 entry into host cells

COVID-19: HLA class I genotypes and mortality

Early high-titer convalescent plasma prevents 75% of severe COVID-19 in elderly

Researchers develop new search engine to investigate viral sequences in COVID-19

Marinomed to initiate clinical trial with Carragelose for preventing COVID19 in frontline healthcare staff

Favorable clinical outcome for ivermectin in COVID-19 animal model

Thromboembolism in COVID-19 patients associated with higher risk of mortality

Scientists studying aerodynamics of infectious disease reveal ways to reduce indoor SARS-CoV-2 transmission

Septic shock and pneumonia triggered by SARS-CoV-2 could be treated by radiation-activated MSCs

Duke-NUS expert joins international taskforce to study the origins of SARS-CoV-2 virus

New CDC report describes COVID-19 in NYC in early spring

Mildly symptomatic COVID-19 patients may be contagious for longer than previously thought

Repeat infection following COVID-19 recovery may not pose risk to close contacts

SARS-CoV-2's spike protein mutations have slowed, study finds

How COVID-19 compares to other respiratory illnesses

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

Nasal dryness could be an early warning sign of COVID-19

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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