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An antiviral regimen based on biomimetic polymers for COVID-19

In a new study published on the bioRxiv* preprint server, scientists proposed the aforementioned mechanism of action (MOA) and have validated it using electron photomicrographs of murine cytomegalovirus (MCMV), which were incubated with a nanoviricide.

30 Nov 2021

New strategy for antibodies to distort viruses discovered

It is widely understood that antibodies neutralize viruses by latching onto their surfaces and blocking them from infecting host cells.

30 Nov 2021

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers investigate potentially amyloidogenic peptide fragments that could be associated with the neurological symptoms of COVID-19 and long-COVID.

30 Nov 2021

The mode of action of essential proteins involved in cancer and Alzheimer´s deciphered

The proteins that belong to the HAT family are essential for life as they transport amino acids across the cell membrane. Although the members of this family are practically identical, some transport certain amino acids and not others.

29 Nov 2021

Researchers outline how advances in neuroscience demand high-performance computing technology

In the latest issue of Science, Katrin Amunts and Thomas Lippert explain how advances in neuroscience demand high-performance computing technology and will ultimately need exascale computing power.

29 Nov 2021

Tomosyn protein's key contribution to heterogeneity of neurons revealed

The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their "plasticity," or ability to change those connections when new information has to be remembered, when their circuit partners change, or other conditions emerge.

29 Nov 2021

SARS-CoV-2 Omicron variant: What we know so far

On November 24, 2021, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) variant was first reported to the World Health Organization (WHO) from South Africa.

28 Nov 2021

New mechanism involved in early melanoma metastasis discovered

How tumors manipulate their environment to advance is one of the big questions that Peinado has been trying to answer for years.

25 Nov 2021

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Scientists investigate the neuroinvasive potential of SARS-CoV-2 and the role of tunneling nanotubes (TNTs) in spreading the infection to neighboring cells.

23 Nov 2021

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers recently used bioinformatics analysis techniques to explore the diseases caused by SARS-CoV-2 infection in the human digestive tract.

22 Nov 2021

Novel technique solves structure of the HIV capsid alone and in complex with host factors

A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.

21 Nov 2021

Scientists unravel near-atomic-scale structure of depression-linked brain receptor

Scientists at Scripps Research, Florida have determined the near-atomic-scale structure of an unusual brain-cell receptor called GPR158, which has been linked to depression and anxiety.

20 Nov 2021

Cancer cells disarm cellular attackers by extending out nanoscale tentacles

To grow and spread, cancer cells must evade the immune system. Investigators from Brigham and Women's Hospital and MIT used the power of nanotechnology to discover a new way that cancer can disarm its would-be cellular attackers by extending out nanoscale tentacles that can reach into an immune cell and pull out its powerpack.

18 Nov 2021

Structure of SARS-CoV-2 spike protein postfusion

A new study published in PNAS proposes a higher resolution in situ structure of the SARS-CoV-2 spike protein in its postfusion state.

18 Nov 2021

Scientists use advanced microscopes to delve deeper into protein degradation process

Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals between cells.

17 Nov 2021

Lung autopsies provide a clearer picture of how SARS-CoV-2 virus spreads and causes damage

Lung autopsy and plasma samples from people who died of COVID-19 have provided a clearer picture of how the SARS-CoV-2 virus spreads and damages lung tissue.

17 Nov 2021

Proposed acquisition of Life Sciences manufacturer Adaptas Solutions for $271m

IMI plc (“IMI” or the “Group”) announces the proposed acquisition of Adaptas Solutions (“Adaptas”) for an enterprise value of $271m (£202m1).

From Norgren Life Science 17 Nov 2021

SARS-CoV-2 protease suppresses host immune response by cleaving NEMO

A recent study conducted by a team of US-based scientists has highlighted a novel function of 3C-like protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The protease has been found to cleave a human immune signaling protein called NF-kB Essential Modulator (NEMO) and disrupt the host immune response.

16 Nov 2021

Ensemble cryo-electron microscopy uncovers conformational states of the nsp13 helicase of SARS-CoV-2

With this background, the goal of a new study published on the bioRxiv* preprint server was to use cryo-electron microscopy to investigate the nsp13 helicase conformational states in order to gain insights of how nsp13 functions during viral transcription/replication.

16 Nov 2021

Electron News and Research

An antiviral regimen based on biomimetic polymers for COVID-19

New strategy for antibodies to distort viruses discovered

Potentially neurotoxic SARS-CoV-2 protein fragments

The mode of action of essential proteins involved in cancer and Alzheimer´s deciphered

Researchers outline how advances in neuroscience demand high-performance computing technology

Tomosyn protein's key contribution to heterogeneity of neurons revealed

SARS-CoV-2 Omicron variant: What we know so far

New mechanism involved in early melanoma metastasis discovered

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Novel technique solves structure of the HIV capsid alone and in complex with host factors

Scientists unravel near-atomic-scale structure of depression-linked brain receptor

Cancer cells disarm cellular attackers by extending out nanoscale tentacles

Structure of SARS-CoV-2 spike protein postfusion

Scientists use advanced microscopes to delve deeper into protein degradation process

Lung autopsies provide a clearer picture of how SARS-CoV-2 virus spreads and causes damage

Proposed acquisition of Life Sciences manufacturer Adaptas Solutions for $271m

SARS-CoV-2 protease suppresses host immune response by cleaving NEMO

Ensemble cryo-electron microscopy uncovers conformational states of the nsp13 helicase of SARS-CoV-2

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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