Genes News and Research

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Key gene involved in transmission of African sleeping sickness identified

Life scientists from UCLA and the University of Bern have identified a key gene in the transmission of African sleeping sickness -- a severe disease transmitted by the bite of infected tsetse flies, which are common in sub-Saharan Africa.

10 Apr 2019

Study relates DNA methylation levels to obesity

DNA methylation is a mechanism that regulates whether genes are "on" or "off" and is influenced by hereditary and environmental factors, as well as lifestyle and nutritional habits.

10 Apr 2019

Genetics may play a role in developing cancer therapy-induced cardiomyopathy

Recent advances in the development of cancer therapies have increased long-term survival and prognosis.

10 Apr 2019

Large-scale screen efficiently identifies drugs that are potent cancer-killers

UC San Francisco scientists have designed a large-scale screen that efficiently identifies drugs that are potent cancer-killers when combined, but only weakly effective when used alone.

10 Apr 2019

New bioinformatics method helps scientists to understand differences in gene regulation in cells

A Belgian team of computational biologists led by Stein Aerts has developed a new bioinformatics method called cisTopic.

10 Apr 2019

Scientists develop new CRISPR-based 'allelic drive'

New CRISPR-based gene drives and broader active genetics technologies are revolutionizing the way scientists engineer the transfer of specific traits from one generation to another.

10 Apr 2019

Eight-year study identifies potential new way to treat extreme childhood food allergy

An eight-year hunt for the cells that drive the extreme childhood food allergy eosinophilic esophagitis has identified a potential new way to treat the disease while also raising questions about a dietary supplement often taken to reduce bowel inflammation.

9 Apr 2019

Study suggests novel therapeutic strategy for ALS

In a study published online in Brain on April 1, researchers from Dr. XU Jin's lab at the Institute of Neuroscience of the Chinese Academy of Sciences and their collaborators revealed a new cellular mechanism for amyotrophic lateral sclerosis, suggested a novel therapeutic strategy targeting the RNA degradation pathway, and identified an asthma drug as a potential medication for ALS.

9 Apr 2019

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Researchers from University of Southern Denmark, Wellcome Sanger Institute and BGI, today published a study in the journal Genome Biology comparing the library preparation and sequencing platforms for single-cell RNA-sequencing.

9 Apr 2019

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

In a landmark study, a group of U.S. scientists from Johns Hopkins, Stanford University and other institutions has found no long-lasting, major differences between the epigenomes of astronaut Scott Kelly, who spent a year in space aboard the International Space Station, and his twin brother, Mark, who remained on Earth.

9 Apr 2019

Study reveals how higher educational attainment may stave off cognitive decline

Prefrontal brain regions linked to higher educational attainment are characterized by increased expression of genes involved in neurotransmission and immunity, finds a study of healthy older adults published in JNeurosci.

From Society for Neuroscience 9 Apr 2019

Early molecular signs of high-risk pregnancy revealed

Women who have healthy pregnancies tend to show distinct changes in the activities of immune genes starting early in pregnancy, while women who have complicated pregnancies tend to show clear departures from that pattern, according to a new study from a team led by researchers at Weill Cornell Medicine and Hospital for Special Surgery.

9 Apr 2019

Testing how well wastewater disinfection methods affect antibiotic resistance genes

Each year at least 2 million Americans are infected with bacteria that cannot be treated with antibiotics, and at least 23,000 of these people die, according to the Centers for Disease Control.

9 Apr 2019

New findings create opportunity to test new treatments for sarcoma

The origin of certain cancers in the sarcoma group is associated with a hitherto unknown interaction among different proteins. Findings now being presented create the opportunity to test new treatments of these forms of sarcoma.

9 Apr 2019

Anti-inflammatory medicine can be effective in treating people with depression

The World Health Organization calls depression one of the most serious mental disorders, and researchers around the world are trying to improve treatment of the disease.

8 Apr 2019

Study of pregnant women with lupus identifies early indicators of pregnancy complications

A study of pregnant women with systemic lupus erythematosus has identified early changes in the RNA molecules present in the blood that could be used to determine the likelihood of them developing preeclampsia.

8 Apr 2019

Immune cells key to predicting outcomes in cancer patients, study suggests

Scientists have identified key changes in immune cells within cancerous tumors that could help improve the development of treatments.

8 Apr 2019

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5 in the journal Molecular Therapy.

8 Apr 2019

Study reveals immune evasion strategy developed by cytomegaloviruses

Owl monkey cytomegalovirus produces a decoy molecule A43 to evade detection and destruction by immune cells in their hosts, according to a study published April 4 in the open-access journal PLOS Pathogens by Ana Angulo of the University of Barcelona, and colleagues.

8 Apr 2019

Researchers identify gut protein essential for neonatal mice to fight infections

Scientists have identified a protein critical to the immune system development and antibody production in mice, which could contribute to understanding the gut defense mechanism in infants.

8 Apr 2019

Genes News and Research

Key gene involved in transmission of African sleeping sickness identified

Study relates DNA methylation levels to obesity

Genetics may play a role in developing cancer therapy-induced cardiomyopathy

Large-scale screen efficiently identifies drugs that are potent cancer-killers

New bioinformatics method helps scientists to understand differences in gene regulation in cells

Scientists develop new CRISPR-based 'allelic drive'

Eight-year study identifies potential new way to treat extreme childhood food allergy

Study suggests novel therapeutic strategy for ALS

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

Study reveals how higher educational attainment may stave off cognitive decline

Early molecular signs of high-risk pregnancy revealed

Testing how well wastewater disinfection methods affect antibiotic resistance genes

New findings create opportunity to test new treatments for sarcoma

Anti-inflammatory medicine can be effective in treating people with depression

Study of pregnant women with lupus identifies early indicators of pregnancy complications

Immune cells key to predicting outcomes in cancer patients, study suggests

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

Study reveals immune evasion strategy developed by cytomegaloviruses

Researchers identify gut protein essential for neonatal mice to fight infections

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