Neurons News and Research

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Price tag from Alzheimer's disease will skyrocket over the next 25 years

The study prompted a new coalition of researchers, health care providers, business leaders and senior advocates to call for an "all-out push" to find a cure.

17 Mar 2006

Cognitive impairment appears to be common in Lou Gehrig disease

In a study of 40 patients with amyotrophic lateral sclerosis (ALS), about one-third showed evidence of cognitive impairment, but these deficits did not appear to be related to survival, according to a study in the March issue of Archives of Neurology.

15 Mar 2006

Scientists have gained valuable new insight into the biology of aggressive, incurable brain tumors

A research study published in the March issue of Cancer Cell uses gene expression profiling to identify molecular profiles and signaling pathways associated with tumor aggressiveness and disease progression.

15 Mar 2006

Valproic acid may help slow the progression of dementia

Researchers have found that a common anticonvulsant drug improved cognitive function and appeared to restore nerve cells in the brains of patients with HIV-related dementia. The results of the Phase I clinical trial are published in the March issue of the scientific journal Neurology.

14 Mar 2006

Stroke researchers have traced the major cause of the death of brain cells

In the neurological train wreck that is stroke, researchers have traced the major cause of the death of brain cells due to artery blockage or bleeding in the brain.

13 Mar 2006

Trial explores safety and efficacy of injecting human stem cells directly into the brain to treat fatal pediatric neurodegenerative disorder

Researchers in Doernbecher Children's Hospital at Oregon Health & Science University will begin a Phase I clinical trial using stem cells in infants and children with a rare neurodegenerative disorder that affects infants and children.

13 Mar 2006

Disturbance of serotonin can lead to sudden infant death syndrome

University of Chicago researchers and colleagues have found strong support that a disturbance of a specific neurochemical can lead to sudden infant death syndrome, the primary cause of death before age 1 in the United States.

13 Mar 2006

Yale School of Medicine expands research using transcranial magnetic stimulation for schizophrenia

Yale School of Medicine researchers are recruiting patients nationally for a clinical trial using transcranial magnetic stimulation (TMS) to help still the voices that are so troubling to some persons with schizophrenia.

9 Mar 2006

Thalidomide, Lenalidomide show promise against Lou Gehrig's disease

New animal research suggests that two well-studied drugs, thalidomide and its derivative, lenalidomide, might extend the survival of patients with the neurological disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

9 Mar 2006

Penn researchers study link between potassium and sodium channels aiming at new treatments for neurological diseases

Researchers at the University of Pennsylvania School of Medicine have discovered the mechanism that facilitates how two ion channels collaborate in the control of electrical signals in the brain.

9 Mar 2006

Important milestone in understanding the neural circuitry that coordinates walking movements

Researchers at the Salk Institute for Biological Studies have identified an important circuit in the spinal cord that controls the speed with which our leg muscles contract and relax.

9 Mar 2006

Cornell develops technique for making living, functional cells glow

The development gives researchers insights into how hearts develop in living mouse embryos and could improve our understanding of irregular heartbeats, known as arrhythmias, as well as open doors to observing cellular processes to better understand basic physiology and disease.

9 Mar 2006

Discovery of compound that reduces hallmark lesions of Alzheimer's disease in mice

Researchers at UC Irvine have found that a new compound not only relieves the cognitive symptoms of Alzheimer's disease, but also reduces the two types of brain lesions that are hallmarks of this devastating disease, thereby blocking its progression.

7 Mar 2006

Genes play a key role in stress response

Both nature and nurture - genetic makeup and the environment experienced through life - combine to influence health and well-being, Duke University Medical Center researchers and their colleagues have determined in four new studies.

7 Mar 2006

Researchers discover cause of episodic ataxia type-2

Researchers at the Albert Einstein College of Medicine of Yeshiva University have discovered the underlying cause of a type of ataxia, hereditary disorders characterized by poor balance, loss of posture and difficulty performing rapid coordinated movement.

7 Mar 2006

A less active brain serotonin system is associated with early hardening of the arteries

These findings, which are the first to establish a link between serotonin messages in the brain and atherosclerosis, could lead to an entirely new strategy for preventing heart disease and stroke, say the researchers.

7 Mar 2006

Scientists reprogramme malignant melanoma cells to become normal pigment cells

Scientists at Northwestern University and the Stowers Institute for Medical Research have reprogrammed malignant melanoma cells to become normal melanocytes, or pigment cells, a development that may hold promise in treating of one of the deadliest forms of cancer.

1 Mar 2006

Cell-death mechanism linked to developmental and degenerative brain disorders

Conclusive evidence that neurodevelopmental disorders such as mental retardation and neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and ataxias can be caused, at least in part, by specific gene defects that interfere with the electrical impulses of rapid-firing brain nerve cells called bursting neurons.

1 Mar 2006

Spinocerebellar ataxia and other neurodegenerative diseases might be treatable with drugs that alter the activity of potassium channels

For the first time, researchers have linked mutations in a gene that regulates how potassium enters cells to a neurodegenerative disease and to another disorder that causes mental retardation and coordination problems.

27 Feb 2006

PET and MR imaging reveals white matter degeneration in Huntington's

Using both brain function (PET) and anatomical structure (MR) imaging studies, Italian researchers - within the context of an Italian-British collaboration - discovered that degenerative and dysfunctional events occur in individuals many years before the onset of Huntington's disease - particularly in the brain's white matter - an area not previously considered primarily involved with the disease.

24 Feb 2006

Neurons News and Research

Price tag from Alzheimer's disease will skyrocket over the next 25 years

Cognitive impairment appears to be common in Lou Gehrig disease

Scientists have gained valuable new insight into the biology of aggressive, incurable brain tumors

Valproic acid may help slow the progression of dementia

Stroke researchers have traced the major cause of the death of brain cells

Trial explores safety and efficacy of injecting human stem cells directly into the brain to treat fatal pediatric neurodegenerative disorder

Disturbance of serotonin can lead to sudden infant death syndrome

Yale School of Medicine expands research using transcranial magnetic stimulation for schizophrenia

Thalidomide, Lenalidomide show promise against Lou Gehrig's disease

Penn researchers study link between potassium and sodium channels aiming at new treatments for neurological diseases

Important milestone in understanding the neural circuitry that coordinates walking movements

Cornell develops technique for making living, functional cells glow

Discovery of compound that reduces hallmark lesions of Alzheimer's disease in mice

Genes play a key role in stress response

Researchers discover cause of episodic ataxia type-2

A less active brain serotonin system is associated with early hardening of the arteries

Scientists reprogramme malignant melanoma cells to become normal pigment cells

Cell-death mechanism linked to developmental and degenerative brain disorders

Spinocerebellar ataxia and other neurodegenerative diseases might be treatable with drugs that alter the activity of potassium channels

PET and MR imaging reveals white matter degeneration in Huntington's

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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