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Nervous system relies on guidance cues for neuronal axons to reach destinations

Similar to the dozens of Sherpas that guide hikers up treacherous Himalayan mountains to reach a summit, the nervous system relies on elaborate timing and location of guidance cues for neuronal axons--threadlike projections--to successfully reach their destinations in the body.

25 Mar 2019

Study explains how bright colors evolved and diversified in male guppies

Striking traits seen only in males of some species - such as colorful peacock feathers or butterfly wings - are partly explained by gene behavior, research suggests.

25 Mar 2019

Antidepressant drugs may not work when neurons are out of shape

elective serotonin reuptake inhibitors are the most commonly prescribed medication for major depressive disorder, yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD.

22 Mar 2019

MSU professor receives NSF CAREER grant for biosensor diagnostics

One day, a technician in a small, rural hospital may be able to reliably diagnose breast cancer, Alzheimer's disease or traumatic brain injury using a tab of paper that would change color like a pH strip dipped in vinegar.

22 Mar 2019

Study provides new pathway for controlling inflammation

UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection.

22 Mar 2019

Study shows how cooperative breeding could increase lifespan

Seychelles warblers live and breed in family groups on the tiny island of Cousin. In each group, a dominant female and male reproduce.

22 Mar 2019

Researchers identify genes responsible for safener efficacy in grain sorghum

Weeds often emerge at the same time as vulnerable crop seedlings and sneak between plants as crops grow. How do farmers kill them without harming the crops themselves?

22 Mar 2019

City of Hope exhibits current studies and data on cancer therapies at AACR

City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, will showcase ongoing studies and data on chimeric antigen receptor T cell therapy, immunotherapy against solid tumors and more at the American Association for Cancer Research annual meeting from March 29 through April 3 in Atlanta.

22 Mar 2019

Thermally abused cooking oil may promote progression of breast cancer

A new study in mice suggests that consuming the chemical compounds found in thermally abused cooking oil may trigger genetic changes that promote the progression of late-stage breast cancer.

22 Mar 2019

Knowing causative genes of osteoporosis may open door to more effective treatments

Scientists have harnessed powerful data analysis tools and three-dimensional studies of genomic geography to implicate new risk genes for osteoporosis, the chronic bone-weakening condition that affects millions of people.

22 Mar 2019

Study: Female birds have longer, healthier lifespan when they have help raising offspring

Female birds age more slowly and live longer when they have help raising their offspring, according to new research from the University of East Anglia.

22 Mar 2019

Study finds how Salmonella bacteria sense presence of bile acids in their surroundings

When bacteria enter the digestive tracts of their hosts, including humans, they encounter a highly acidic environment.

21 Mar 2019

New study contradicts previous views on skeletal growth mechanism

An international group of scientists under the supervision of a staff member of Sechenov University and Karolinska Institute found out that earlier views on the mechanisms that provide and regulate skeletal growth were wrong.

21 Mar 2019

UIC scientists identify hidden proteins in bacteria

Scientists at the University of Illinois at Chicago have developed a way to identify the beginning of every gene -- known as a translation start site or a start codon -- in bacterial cell DNA with a single experiment and, through this method, they have shown that an individual gene is capable of coding for more than one protein.

21 Mar 2019

MIT announces creation of the Alana Down Syndrome Center

As part of MIT's continued mission to help build a better world, the Institute announced the creation of the Alana Down Syndrome Center, an innovative new research endeavor, technology development initiative, and fellowship program launched with a $28.6 million gift from Alana Foundation, a nonprofit organization started by Ana Lucia Villela of São Paulo, Brazil.

21 Mar 2019

CRISPR/Cas libraries could revolutionize drug discovery

CRISPR/Cas enables the targeted deactivation of genes by cutting DNA at pre-determined sites. This is accomplished by providing the Cas enzyme with a genetic zip code.

20 Mar 2019

Human microbiome metabolites enhance colon injury by enterohemorrhagic E. coli, study shows

It remains mysterious why humans get infected by some bacterial or viral pathogens relatively easily while animals that have very similar tissues and immune functions do not.

20 Mar 2019

Researchers track effects of epigenetic marks carried by sperm chromosomes

As an organism grows and responds to its environment, genes in its cells are constantly turning on and off, with different patterns of gene expression in different cells. But can changes in gene expression be passed on from parents to their children and subsequent generations?

20 Mar 2019

Merck to collaborate with GenScript for plasmid and virus manufacturing in China

Merck, a leading science and technology company, today announced the signing of a non-binding Memorandum of Understanding with Chinese biotech company GenScript for a strategic alliance focusing on plasmid and viral vector manufacturing.

From Merck 20 Mar 2019

Researchers discover previously unknown mechanism by which cells can sense oxygen

Researchers from the University of Oulu and Harvard University have found a previously unknown mechanism by which cells in the body sense oxygen. Lack of oxygen had a direct influence on the functioning of genes, and prevented cell differentiation.

20 Mar 2019