Antibodies News and Research

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Novel ways to boost vaccination or natural defenses

Our bodies rely on the production of potent, or 'high affinity', antibodies to fight infection. The process is very complex, yet Sydney scientists have discovered that it hinges on a single molecule, a growth factor, without which it cannot function.

8 Jul 2008

Potential new way to vaccinate against avian flu

Researchers at the University of Pennsylvania School of Medicine have identified a potential new way to vaccinate against avian flu. By delivering vaccine via DNA constructed to build antigens against flu, along with a minute electric pulse, researchers have immunized experimental animals against various strains of the virus.

1 Jul 2008

Australian scientists discover reason for extreme allergic reactions

Australian scientists believe they have discovered why some people experience extreme allergic reactions and their find could lead to new treatments for what seems to be an increasingly common problem.

1 Jul 2008

New approach to HIV vaccine research taps Rochester expertise

A new national effort to create a vaccine against HIV will include work by a University of Rochester Medical Center rheumatologist who is an expert on a portion of the immune system that has sometimes gotten short shrift in the fight against HIV.

30 Jun 2008

Discovery of an important factor in the development of B-cell lymphomas

Researchers at National Jewish Medical and Research Center have discovered an important factor in the development of B-cell lymphomas, one of the fastest growing forms of cancer. The B-cell receptor on the surface of B cells can cooperate with the MYC oncogene to accelerate the development of lymphomas.

24 Jun 2008

Apollo acquisition boosts NZ biotech Symansis

New Zealand biotech Symansis has purchased Australian company Apollo Cytokine Research for A$500,000 (NZ$627,000) to build on its unique cell signaling science and fast track expansion into new international markets.

24 Jun 2008

Genetic mutation and cat exposure at birth may increase a child's risk of developing eczema

A gene mutation and cat exposure at birth may increase a child's risk of developing eczema during their first year according to a study published in PLoS Medicine. Researchers led by Professor Hans Bisgaard (University Hospital Gentofte, Copenhagen, Denmark) studied the association between mutations in the filaggrin gene (FLG) and exposure to environmental factors with the development of eczema.

24 Jun 2008

Hedgehog signaling is critical for maintenance of the adult coronary vasculature

A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis.

23 Jun 2008

40% of gay men with HIV don't know they are infected

A survey of gay men questioned at gay venues in cities across the UK has found that most of those with undiagnosed HIV infection assumed they were HIV negative. Most of them had previously tested negative and thought they were in the clear. It's feared these men could unknowingly be putting others at risk. These are the findings of a study led by Dr Lisa Williamson at the MRC Social and Public Health Sciences Unit in Glasgow and published in the journal, AIDS.

17 Jun 2008

Radioimmunotherapy targeting viral antigens shows potential to treat or prevent viral cancers

A new study, presented at the Society of Nuclear Medicine's 55th Annual Meeting, shows that radioimmunotherapy (RIT) targeting viral antigens offers a novel option to treat-or even prevent-many viral cancers by targeting cancer cells expressing viral antigens or infected cells before they convert into malignancy.

16 Jun 2008

Peregrine Pharmaceuticals awarded two new U.S. patents for targeted anti-aminophospholipid agents

Peregrine Pharmaceuticals, Inc. today reported the issuance of two U.S. patents that significantly broaden the company's intellectual property leadership in the field of targeted anti-aminophospholipid agents.

16 Jun 2008

Victorian Government invests heavily in life-saving medical technology

A new trans-Tasman $30 million research commercialisation fund for local universities - announced today in San Diego by Premier of Victoria John Brumby and in New Zealand by New Zealand's Minister for Economic Development Pete Hodgson - will drive research into life-saving medical technology.

16 Jun 2008

Breastfeeding support lacking in U.S. hospitals and birth centers

Many birth facilities in the United States are not providing maternity care that is fully supportive of breastfeeding, according to a study in today's Morbidity and Mortality Weekly Reports (MMWR), a publication of the Centers for Disease Control and Prevention.

15 Jun 2008

Evolution may have lumbered humans with allergy problems

Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have discovered how evolution may have lumbered humans with allergy problems.

15 Jun 2008

Lupus more severe in patients with ancestry from southern Europe

Systemic lupus erythematosus (SLE) patients with a higher percentage of ancestry from southern Europe have more severe disease manifestations, according to new research presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France.

11 Jun 2008

Compugen announces discovery of novel drug targets for cancer antibody therapeutics

Compugen Ltd. announced today the discovery of more than ten novel targets of antibody therapy for various types of solid and hematopoietic cancer.

11 Jun 2008

Maxygen receives approval for trial of factor VIIa in UK

Maxygen, Inc. today announced that it has filed a Clinical Trial Authorization (CTA) and received the necessary approvals in the United Kingdom to initiate a first-in-human Phase I trial of MAXY-VII in hemophilia patients.

11 Jun 2008

Oxygen-rich lifesaving efforts pose risk for respiratory infections

Each year, thousands of premature infants battle to breathe. Thanks to life-saving interventions developed in the past couple decades - steroids given to their mothers to stall pre-term labor, mechanical ventilation, air enriched with extra oxygen, and surfactant, a crucial wetting agent that makes breathing less work - most of these newborns survive with enough lung function to grow and go home.

11 Jun 2008

Scientists identify a key regulator of DNA mutations

As a general rule, your DNA is not something you want rearranged. But there are exceptions - especially when it comes to fighting infections. Since the number of microbes in the world far surpasses the amount of human DNA dedicated to combat them, specialized cells in the immune system have adopted an ingenious, if potentially disastrous, strategy for making antibodies. These cells, called B lymphocytes, intentionally mutate their own DNA to ward off invaders they have never seen before.

9 Jun 2008

Role of breastfeeding in preventing infant death, HIV infection in developing countries

In many poor countries, mothers with HIV face a stark choice: to nurse their infants, and risk passing on HIV through their breast milk - or to formula feed, and deprive their infants of much of the natural immunity needed to protect against fatal diseases of early infancy. Now, two studies supported by the National Institutes of Health offer insights into preventing early death and HIV infection among breastfeeding infants of mothers with HIV in these countries.

5 Jun 2008