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Keyhole surgery for liver cancer results in better outcomes and quality of life

Those who had tumors removed from their livers with keyhole surgery had fewer complications, a better quality of life and similar long-term oncologic outcomes, a new PhD thesis shows.

10 May 2021

Inflammasomes could play an important role in the development of obesity-related colon cancer

New research presented at this year's European Congress on Obesity (held online, 10-13 May) finds evidence that structures called inflammasomes (a part of the innate immune system that helps to regulate inflammation) could play an important role in the development of obesity-associated colon cancer.

10 May 2021

Indian SARS-CoV-2 variant shows enhanced host cell entry and immune evasion

A study conducted by researchers in Germany has found that the B.1.617 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has emerged in India entered certain types of lung and intestine cells with slightly increased efficiency compared with the original wild-type strain.

6 May 2021

Daily intake of two or more sugar-sweetened drinks associated with higher bowel cancer risk

Drinking two or more daily sugar-sweetened beverages in adulthood is linked to a doubling in the risk of bowel cancer before the age of 50--at least in women, finds research published online in the journal Gut.

6 May 2021

Study shows possible link between intestinal polyps in close relatives and colorectal cancer risk

Cancer of the colon and rectum is one of the deadliest forms of cancer, and has in recent years affected growing numbers of young people.

4 May 2021

SARS-CoV-2 study in human gut organoids

Most of the major life-threatening symptoms of COVID-19 disease are associated with the host's generation of an exacerbated pro-inflammatory immune response. Many studies have correlated the intensity of the immune response with the severity of disease.

3 May 2021

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Processed diets may promote diseases characterized by low-grade infection and inflammation

Processed diets, which are low in fiber, may initially reduce the incidence of foodborne infectious diseases such as E. coli infections, but might also increase the incidence of diseases characterized by low-grade chronic infection and inflammation such as diabetes, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

28 Apr 2021

Researchers investigate how oxygen radicals protect against cancer

Originally, oxygen radicals - reactive oxygen species, or ROS for short - were considered to be exclusively harmful in the body.

26 Apr 2021

Interleukin 11-producing fibroblasts can be potential therapeutic targets for treating colorectal cancer

IL-11 is known to promote the development of colorectal cancer in humans and mice, but when and where IL-11 is expressed during cancer development is unknown.

22 Apr 2021

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

Today, the U.S. Food and Drug Administration granted accelerated approval to Jemperli (dostarlimab) for treating patients with recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing chemotherapy and whose cancers have a specific genetic feature known as dMMR (which contain abnormalities that affect the proper repair of DNA inside the cell), as determined by an FDA-approved test.

22 Apr 2021

New blood-based test detects lymph node metastasis in individuals with high-risk T1 colorectal cancer

Scientists at City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, have developed a novel, noninvasive liquid biopsy test for detecting lymph node metastasis in individuals with high-risk T1 colorectal carcinoma.

21 Apr 2021

1 in 6 patients with colorectal cancer found to have inherited genetic mutations

A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next.

20 Apr 2021

Defects in specific goblet cells may be a factor contributing to ulcerative colitis

There are many variants of "goblet cells" in the intestines and they seem to have different functions, according to a new study from the University of Gothenburg.

19 Apr 2021

Three teams selected to receive the first awards from Dartmouth Innovations Accelerator for Cancer

Three teams of Dartmouth researchers have been selected to receive the first awards from the Dartmouth Innovations Accelerator for Cancer.

17 Apr 2021

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma.

16 Apr 2021

Colon News and Research

Keyhole surgery for liver cancer results in better outcomes and quality of life

Inflammasomes could play an important role in the development of obesity-related colon cancer

Indian SARS-CoV-2 variant shows enhanced host cell entry and immune evasion

Daily intake of two or more sugar-sweetened drinks associated with higher bowel cancer risk

Study shows possible link between intestinal polyps in close relatives and colorectal cancer risk

SARS-CoV-2 study in human gut organoids

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

Processed diets may promote diseases characterized by low-grade infection and inflammation

Researchers investigate how oxygen radicals protect against cancer

Interleukin 11-producing fibroblasts can be potential therapeutic targets for treating colorectal cancer

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

New blood-based test detects lymph node metastasis in individuals with high-risk T1 colorectal cancer

1 in 6 patients with colorectal cancer found to have inherited genetic mutations

Defects in specific goblet cells may be a factor contributing to ulcerative colitis

Three teams selected to receive the first awards from Dartmouth Innovations Accelerator for Cancer

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

Researchers map the changing trends of cancer burden worldwide and in China

Pigs’ brain size and digestive system are excellent analogs for human newborns

ACE2 homology in laboratory and wild animals

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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