Drug Delivery News and Research

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Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.

Researchers unlock better treatment strategy for viral diseases

RMIT University scientists in Melbourne, Australia, have led an international collaboration that potentially unlocks better treatment of viral diseases, including the flu and common cold.

12 Jul 2017

Researchers develop new biocompatible materials for soft-tissue adhesion

Researchers at Okayama University describe in Acta Biomaterialia a new type of biocompatible adhesive material. The adhesive, made from nanoparticles of hydroxyapatite, glues both synthetic hydrogels and mouse soft tissue, providing a promising alternative to organic materials currently in use for clinical applications.

30 Jun 2017

CWRU researcher receives major NIH grants to develop microscopic drug-delivery systems

Nicole F. Steinmetz, PhD, George J. Picha Professor in Biomaterials, member of the Case Comprehensive Cancer Center, and Director of the Center for Bio-Nanotechnology at Case Western Reserve School of Medicine, has received two major grants from the National Institutes of Health to develop microscopic drug-delivery systems for patients living with breast cancer, and patients at risk for serious blood clots.

29 Jun 2017

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Many potent anti-cancer drugs have major drawbacks -- they fail to mix with water, which means they will have a limited solubility in blood, and they lack selectivity to cancer cells.

29 Jun 2017

Injecting plant-based nanoparticles and chemotherapy drug helps halt tumor progression in mice

Researchers from Case Western Reserve University School of Medicine in collaboration with researchers from Dartmouth Geisel School of Medicine and RWTH Aachen University have adapted virus particles- that normally infect potatoes- to serve as cancer drug delivery devices for mice.

28 Jun 2017

Ingredient found in cosmetic cleaners can control wettability of the skin

It's possible to alter the wettability of your skin using an ingredient commonly found in cosmetic cleaners, according to new research from Binghamton University, State University of New York.

28 Jun 2017

OIST researchers create taurine-modified photosensitizer for brain cancer therapy

Photodynamic therapy is often used to treat brain tumors because of its specificity—it can target very small regions containing cancerous cells while sparing the normal cells around it from damage. It works by injecting a drug called a photosensitizer into the bloodstream, where it gathers in cells, and then exposing the drug-filled cells to light.

23 Jun 2017

FDA labeling rule helps providers better explain medication risks and benefits to pregnant, breastfeeding patients

The new U.S. Food and Drug Administration's Pregnancy and Lactation Labeling Rule should help healthcare providers better explain to pregnant and breastfeeding patients the benefits and risks of taking a specific medication.

15 Jun 2017

Magnetic nanoparticle aggregates can induce death of cancer cells

An international team in which a UPM researcher is involved has shown that it is possible to mechanically destroy cancer cells by rotating magnetic nanoparticles attached to them in elongated aggregates.

13 Jun 2017

Scientists create 'immunoswitch' particles that slow cancer growth in test animals

Scientists at Johns Hopkins have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells' defensive properties while switching on a robust anticancer immune response in mice.

8 Jun 2017

Rice scientists use magnets and nanoparticles to make vessels temporarily ‘leaky’

The endothelial cells that line blood vessels are packed tightly to keep blood inside and flowing, but scientists at Rice University and their colleagues have discovered it may be possible to selectively open gaps in those barriers just enough to let large molecules through -- and then close them again.

8 Jun 2017

Dutch scientists design self-destroying nanomotors to deliver and release drugs

Autonomous targeting and release of drugs at their site of action are desired features of nanomedical systems. Now, a team of Dutch scientists has designed a nanomotor that has these functions: An antitumor drug encapsulated in self-propelled, self-assembled stomatocytes is carried across the cellular membrane and released inside the cell upon a chemical redox signal that disassembles the vesicle membrane.

31 May 2017

Rice University scientists develop and evaluate analogs of potent cancer fighters

Rice University scientists have developed and evaluated analogs of potent anti-tumor agents known as epothilones using designs and methods that both improve their biological properties and simplify their manufacture.

31 May 2017

Bioadhesive nanoparticles show potential for drug delivery to specific cells in the brain

A Yale research team has found that by tinkering with the surface properties of drug-loaded nanoparticles, they can potentially direct these particles to specific cells in the brain.

24 May 2017

Nemaura Pharma device addresses needle phobia in diabetics

Results of recent clinical trials carried out on type 1 diabetics by Nemaura Pharma using its Memspatch Insulin Micro-needle Device (IMD) will come as a relief to those who fear needles and injections, a condition medically known as trypanophobia, affecting 10 percent of the world’s population.

18 May 2017

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

By using induced pluripotent stem cells to create endothelial cells that line blood vessels in the brain for the first time for a neurodegenerative disease, University of California, Irvine neurobiologists and colleagues have learned why Huntington's disease patients have defects in the blood-brain barrier that contribute to the symptoms of this fatal disorder.

17 May 2017

Making brain implants smaller could eliminate scarring, extend life of devices

Many diseases, including Parkinson's disease, can be treated with electrical stimulation from an electrode implanted in the brain. However, the electrodes can produce scarring, which diminishes their effectiveness and can necessitate additional surgeries to replace them.

16 May 2017

Drug Delivery News and Research

Further Reading

Researchers unlock better treatment strategy for viral diseases

Researchers develop new biocompatible materials for soft-tissue adhesion

CWRU researcher receives major NIH grants to develop microscopic drug-delivery systems

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Injecting plant-based nanoparticles and chemotherapy drug helps halt tumor progression in mice

Ingredient found in cosmetic cleaners can control wettability of the skin

OIST researchers create taurine-modified photosensitizer for brain cancer therapy

FDA labeling rule helps providers better explain medication risks and benefits to pregnant, breastfeeding patients

Magnetic nanoparticle aggregates can induce death of cancer cells

Scientists create 'immunoswitch' particles that slow cancer growth in test animals

Rice scientists use magnets and nanoparticles to make vessels temporarily ‘leaky’

Dutch scientists design self-destroying nanomotors to deliver and release drugs

Rice University scientists develop and evaluate analogs of potent cancer fighters

Bioadhesive nanoparticles show potential for drug delivery to specific cells in the brain

Nemaura Pharma device addresses needle phobia in diabetics

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

Making brain implants smaller could eliminate scarring, extend life of devices

WSU scientists develop new approach to deliver therapeutics to tumors

New type of eye drop could potentially revolutionize treatment of AMD

New technique uses modified insulin and red blood cells to reduce blood sugar levels

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