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Fluctuation in intracellular calcium ion concentration impacts brain shape

The first step in shaping the brain is that the neural plate, a sheet-like cell layer, curves to form the neural tube. Assistant Professor Makoto Suzuki of the National Institute for Basic Biology, Professor Naoto Ueno, and their colleagues have shown that during the process of neural tube formation a transient increase in the concentration of calcium ions in cells causes these morphological changes and is essential for neural tube formation.

30 Mar 2017

Single dose of siRNA molecule offers protection against heart attack and stroke in high-risk patients

Even a single dose of a specific ribonucleic acid molecule, known as a small interfering RNA (siRNA), offers patients at high risk of cardiovascular disease long-lasting protection against high LDL cholesterol - one of the main risk factors for heart attack and stroke.

30 Mar 2017

Finalists for Pittcon's excellence awards released

Pittcon, the world’s leading conference and exposition for laboratory science, is pleased to announce the selection of eight finalists in the first ever Pittcon Today Excellence Awards conducted by CE Communications, official publishers of Pittcon Today and Pittcon Buzz.

From Pittcon 30 Mar 2017

Study shows protective link between consumption of legumes and risk of developing type 2 diabetes

Legumes are a food group rich in B vitamins, contain different beneficial minerals (calcium, potassium and magnesium) and sizeable amounts of fibre and are regarded as a low-glycemic index food, which means that blood glucose levels increase only slowly after consumption.

30 Mar 2017

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

By engineering an on/off switch into a weakened form of HIV, University of Nebraska-Lincoln researchers have enhanced the safety and effectiveness of a potential vaccine for the virus that has killed approximately 35 million people during the past 35 years.

30 Mar 2017

Rare ‘beneficial’ genetic mutations may provide clues to preventing heart attacks

Natural genetic changes can put some people at high risk of certain conditions, such as breast cancer, Alzheimer's disease or high blood pressure. But in rare cases, genetic errors also can have the opposite effect, protecting individuals with these helpful genetic mistakes from developing common diseases.

30 Mar 2017

Study shows inhibition of transgelin prevents vasculogenic mimicry in breast cancer

An article published in Experimental Biology and Medicine identifies a new signaling pathway involved in breast cancer cell growth. The study, led by Dr. Chan-Wha Kim, from the Department of Biotechnology at Korea University in Seoul, reports that inhibition of the actin-binding protein transgelin prevents vasculogenic mimicry (VM), a process that provides tumor cells with the nutrients required for growth.

29 Mar 2017

Researchers use mathematical modeling to raise density of bones badly degraded by osteoporosis

They may seem rigid and set in their ways, but your bones are actually under constant construction and deconstruction. They give up their nutrient treasures (calcium) to the body and then rebuild in a constant give-and-take sort of rhythm.

29 Mar 2017

Scientists developing new method for drug discovery using simple models and small data sets

Drug discovery is in essence the designing of compounds to interact with disease-related proteins. And in many recent development efforts, this process increasingly relies on "big data" and complex "deep learning", requiring the harnessing of supercomputing power.

29 Mar 2017

Simple finger-prick blood test can help doctors prescribe treatment for depression

Doctors for the first time can determine which medication is more likely to help a patient overcome depression, according to research that pushes the medical field beyond what has essentially been a guessing game of prescribing antidepressants.

29 Mar 2017

Scientists target hunger's complex chemistry to yield promising treatments for obesity

Discoveries of hormones related to weight and appetite in the '90s helped spur a search for obesity treatments targeting those hormones-- with disappointing results.

29 Mar 2017

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

All causes of the most common form of liver cancer, hepatocellular carcinoma, are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.

29 Mar 2017

New discovery opens new therapeutic opportunities for treatment of cancer and tissue fibrosis

Researchers from the Turku Centre for Biotechnology (BTK) in Finland have discovered that a cellular fuel sensor, known to control energy processes in the cells, is involved in the regulation of the contact of cells with their surrounding environment.

29 Mar 2017

Study identifies how BPA may encourage inflammatory breast cancer growth

The chemical bisphenol A, or BPA, appears to aid the survival of inflammatory breast cancer cells, revealing a potential mechanism for how the disease grows, according to a study led by researchers in the Department of Surgery at Duke University School of Medicine and the Duke Cancer Institute.

28 Mar 2017

Survey finds alarming rates of shared decision making for prostate cancer screening

A new study finds that while a blood test that helps to screen for prostate cancer remains common, only 30 percent of men in a large national survey reported having a balanced discussion of the advantages and disadvantages of the screening with their doctor.

28 Mar 2017

TSRI researchers reveal how viruses incapacitate bacterial defense system

Picture bacteria and viruses locked in an arms race. For many bacteria, one line of defense against viral infection is a sophisticated RNA-guided "immune system" called CRISPR-Cas.

28 Mar 2017

Study identifies protein as potential therapeutic target for pancreatic cancer

A protein known as arginine methyltransferase 1 (PRMT1) may be a potential therapeutic target for pancreatic ductal adenocarcinoma, the most common type of pancreatic cancer, and one of the most deadliest with a less than 10 percent, five-year survival rate.

28 Mar 2017

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

HIV is a master of disguise. The virus uses a shield of sugar molecules, called glycans, to hide from the immune system and block antibodies from attacking it.

28 Mar 2017

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, will highlight a variety of basic research and population studies at the annual meeting of the American Association for Cancer Research at the Walter E. Washington Convention Center in Washington, D.C., April 1 to 5.

28 Mar 2017

Researchers shed light on diverse effects of exercise on individuals

In Japan, due to the changes of lifestyle such as less physical activities than before, more and more people suffer from the lifestyle diseases like metabolic syndromes, type-2 diabetes and hypertension.

28 Mar 2017

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G Protein News and Research

Fluctuation in intracellular calcium ion concentration impacts brain shape

Single dose of siRNA molecule offers protection against heart attack and stroke in high-risk patients

Finalists for Pittcon's excellence awards released

Study shows protective link between consumption of legumes and risk of developing type 2 diabetes

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

Rare ‘beneficial’ genetic mutations may provide clues to preventing heart attacks

Study shows inhibition of transgelin prevents vasculogenic mimicry in breast cancer

Researchers use mathematical modeling to raise density of bones badly degraded by osteoporosis

Scientists developing new method for drug discovery using simple models and small data sets

Simple finger-prick blood test can help doctors prescribe treatment for depression

Scientists target hunger's complex chemistry to yield promising treatments for obesity

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

New discovery opens new therapeutic opportunities for treatment of cancer and tissue fibrosis

Study identifies how BPA may encourage inflammatory breast cancer growth

Survey finds alarming rates of shared decision making for prostate cancer screening

TSRI researchers reveal how viruses incapacitate bacterial defense system

Study identifies protein as potential therapeutic target for pancreatic cancer

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

Researchers shed light on diverse effects of exercise on individuals

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

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