Microscopy News and Research

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New model could make the measurement of skin barrier function easier

The skin is the primary physical barrier against harmful substances in the environment. But there is a significant difference in the protective capacity of the skin across individuals.

20 Mar 2023

Computational analysis of large genetic datasets reveals rare disease etiologies

Using a new computational approach they developed to analyze large genetic datasets from rare disease cohorts, researchers at the Icahn School of Medicine at Mount Sinai and colleagues have discovered previously unknown genetic causes of three rare conditions: primary lymphedema (characterized by tissue swelling), thoracic aortic aneurysm disease, and congenital deafness.

17 Mar 2023

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Acute gastroenteritis afflicts adults of all ages, causing significant suffering and inflicting significant costs on the American healthcare system.

16 Mar 2023

Scientists generate 3D ultra-resolution maps of mitochondrial networks in lung tumors

Scientists have long known that mitochondria, the "powerhouses" of cells, play a crucial role in the metabolism and energy production of cancer cells.

15 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

Veterans’ health administration expands deployment of Mikroscan Systems

Mikroscan Technologies, innovators and manufacturers of live robotic microscopy and whole-slide imaging (WSI) systems, announces that it has expanded its relationship with the Veterans’ Administration through the multi-system sale of its SL5-20 Real-Time Telemicroscopy and Digital Pathology systems.

From Mikroscan Technologies 14 Mar 2023

Using convolutional neural network to automate the identification of chromatid cohesion defects

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion.

13 Mar 2023

Research examines the use of Brillouin microscopy to improve acquisition speed, reduce irradiation doses

Diagnostic imaging offers physicians and scientists critical visual representations of internal body structures, greatly enhancing clinical analysis and medical intervention.

10 Mar 2023

Study creates a radical new view of how immune cells recognize threats

Researchers have created a radical new view of how immune cells recognise threats such as viruses. The discovery could be used to design better vaccines and to gain a deeper insight into autoimmune diseases and allergies.

10 Mar 2023

Newly identified therapeutic target could lead to more effective treatment of glaucoma

Indiana University School of Medicine researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.

10 Mar 2023

Super-resolution microscopy method for faster imaging of molecular structures in 3D

LMU researchers have developed a super-resolution microscopy method for the rapid differentiation of molecular structures in 3D.

10 Mar 2023

New community-based diagnostic tool is feasible and effective for diagnosing tuberculosis

A new, low-cost, scalable package for diagnosing tuberculosis (TB) onsite in resource-poor community settings is feasible and effective, according to a new trial.

10 Mar 2023

New ghost imaging algorithm produces higher-resolution image reconstruction with better contrast

Although electron microscopy can already reveal details as small as one nanometer, ongoing research seeks to break through barriers limiting image quality and reducing the optical dose on the samples. Aberration is a common problem in electron microscopy that can reduce the resolution and quality of the images produced.

3 Mar 2023

Gene mutation capable of regulating pain discovered

Pain afflicts at least 1.5 billion people worldwide, and despite the availability of various painkilling drugs, not all forms of pain are treatable.

3 Mar 2023

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Researchers examined the vaccination effects and local antigen expression efficiency of a needle-free vaccination technique involving pyro-drive liquid jet injection (PYRO) to deliver the naked messenger ribonucleic acid (mRNA) to the skin.

3 Mar 2023

Using the origami technique to design RNA nanostructures

Researchers from Aarhus University and Berkeley Laboratory have designed RNA molecules, that folds into nanoscale rectangles, cylinders, and satellites, and have studied their 3D structure and dynamics with advanced nanotechnological methods.

28 Feb 2023

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers reported the circulation of a novel MERS-like coronavirus among Malayan pangolins, Manis javanica HKU4-associated CoV (MjHKU4r-CoV).

21 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

Microscopy News and Research

New model could make the measurement of skin barrier function easier

Computational analysis of large genetic datasets reveals rare disease etiologies

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Scientists generate 3D ultra-resolution maps of mitochondrial networks in lung tumors

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Veterans’ health administration expands deployment of Mikroscan Systems

Using convolutional neural network to automate the identification of chromatid cohesion defects

Research examines the use of Brillouin microscopy to improve acquisition speed, reduce irradiation doses

Study creates a radical new view of how immune cells recognize threats

Newly identified therapeutic target could lead to more effective treatment of glaucoma

Super-resolution microscopy method for faster imaging of molecular structures in 3D

New community-based diagnostic tool is feasible and effective for diagnosing tuberculosis

New ghost imaging algorithm produces higher-resolution image reconstruction with better contrast

Gene mutation capable of regulating pain discovered

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Using the origami technique to design RNA nanostructures

NQO2 gene as a novel potential target in Parkinson’s disease

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo