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iNOS inhibitors may be effective therapies for Alzheimer's disease

A noxious gas speeds up brain degeneration in Alzheimer's disease, according to a study in the November 7 issue of The Journal of Experimental Medicine.

1 Nov 2005

Bumetanide may help treat seizures in newborns

A diuretic drug called bumetanide may serendipitously help treat seizures in newborns, which are difficult to control with existing anticonvulsants, according to a study in the November Nature Medicine.

1 Nov 2005

DCDC2 gene linked to dyslexia

Pediatric researchers at Yale School of Medicine have identified a gene on human chromosome 6 called DCDC2, which is linked to dyslexia, a reading disability affecting millions of children and adults.

30 Oct 2005

Scientists unravel complex mechanisms in the brain that regulate body weight

Scientists are one step closer to unraveling the complex mechanisms in the brain that regulate body weight. Working with mice -- whose appetites are controlled by systems very similar to those in humans – they have identified a specific type of neuron that is essential for feeding behavior.

30 Oct 2005

Scientists say there is less white matter in the frontal lobes of those who struggle with focusing

When it comes to focusing on a task amid distractions, some folks more than 60 years old are as mentally sharp as 22-year-olds. Others struggle. Researchers at the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign have shed some light on why that is.

27 Oct 2005

New understanding of how neurogenesis occurs

Scientists at the Salk Institute for Biological Studies have identified a crucial cellular signal that controls the fate of stem cells in the brains of adult mice.

27 Oct 2005

Northwestern University move closer to new therapies for neurodegenerative disease

French neurologist Jean-Martin Charcot first described amyotrophic lateral sclerosis (ALS) in 1869, but, nearly 140 years later, little is known about the cause of the devastating neurodegenerative disease, and there is no cure.

27 Oct 2005

Cancer drug may be effective for Alzheimer's

According to scientists at the Blanchette Rockefeller Neurosciences Institute and the Marine Biological Laboratory, a cancer drug may stimulate the production of proteins needed for long-term memory, suggesting the compound may a possible treatment for Alzheimer's disease

26 Oct 2005

Scientists find key step in a signaling pathway that helps orchestrate embryonic development

The study, reported in Nature (Oct. 13, 2005), focuses on the Hedgehog family of signaling molecules, which play a central role in directing development of the early embryo's growth and spatial plan, as well as its later organ and limb development. Defects in Hedgehog signaling are a significant cause of some birth defects and cancers.

25 Oct 2005

Blocking a signaling lipid can keep nerves from developing and may even cause neurons to die

Blocking a signaling lipid can keep nerves from developing the arm-like extensions they need to wire the body and may even cause neurons to die, researchers have found.

24 Oct 2005

Diabetes drugs may also prevent nerve degeneration caused by Alzheimer's disease

Recent research has shown a surprising link between Alzheimer’s and diabetes, two of the major health challenges facing society today. According to Dr Holscher modern lifestyle promotes the development of type 2 diabetes, which in turn could drastically increase the number of people to develop Alzheimer’s disease as people with type 2 diabetes are much more likely to develop the disease than healthy people of the same age.

20 Oct 2005

Neurobiologists gain new insights into brain and memory

We often make unwise choices although we should know better. Thunderstorm clouds ominously darken the horizon. We nonetheless go out without an umbrella because we are distracted and forget. But do we?

19 Oct 2005

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Reporting in two companion papers in the October 19 issue of the Journal of Neuroscience, investigators from the Gladstone Institute of Neurological Disease show in genetically engineered mouse models of the disease that the accumulation of Alzheimer-related neurotoxic amyloid-beta (Aâ) peptides can deplete key proteins in a specific memory center of the brain.

18 Oct 2005

Rett syndrome discovery

The gene responsible for Rett syndrome, a devastating neurological disease found mostly in girls, not only silences some genes but in combination with another also regulates alternative splicing, crucial to the formation of proteins -- a finding that may explain the symptoms associated with this puzzling disorder and others related to it

17 Oct 2005

Cannabis boosts brain power in rats

Scientists now say that Cannabis, the third most popular recreational drug after alcohol and tobacco, could boost brain power.

17 Oct 2005

First gene mutation associated with Tourette syndrome

Researchers have identified the first gene mutation associated with Tourette syndrome - opening a new avenue for understanding the complex disorder that causes muscle and vocal tics.

13 Oct 2005

Astrocytes modulate adenosine - thought to be important in controlling wake-to-sleep transitions and epileptic seizures

Researchers at the University of Pennsylvania School of Medicine have demonstrated that star-shaped glial cells in the brain called astrocytes are directly involved in regulating communication between neurons.

10 Oct 2005

Prozac helps learning and memory in people with Huntington's disease

People with Huntington's disease have progressive motor problems, cognitive deficits (dementia) and psychiatric symptoms (the most common is depression) that usually start to appear in mid-life. There is no cure and death usually results within 10 to 20 years of symptom onset, or faster in the childhood-onset form of the disease.

9 Oct 2005

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Two New Jersey research teams are reporting discoveries about the biological nature of psychiatric disorders that may bring them closer to the ultimate goal of finding cures for complex diseases, such as autism and schizophrenia.

9 Oct 2005

The cocktail party problem

Known as "the cocktail party problem," the ability of the brain's auditory processing centers to sort a babble of different sounds, like cocktail party chatter, into identifiable individual voices has long been a mystery.

5 Oct 2005