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Researchers describe neural mechanisms responsible for local search in hungry worms

Perpetually hungry, worms are strategic when it comes to searching for food. The microscopic roundworm Caenorhabditis elegans, or C. elegans, is known to spend up to 20 minutes seeking out snacks in its immediate surroundings before endeavoring to look elsewhere.

27 Feb 2019

Cancer genes’ mutational status influenced by their evolutionary age, regulatory functions

Researchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulated) by specific mechanisms during cancer development.

26 Feb 2019

Novel mechanism behind DNA damage control uncovered

DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species.

26 Feb 2019

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses.

26 Feb 2019

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences, and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases.

26 Feb 2019

Researchers outline targeted therapeutic strategy for triple-negative breast cancer

New findings put forth by the University of Maryland Fischell Department of Bioengineering and researchers from four other academic institutions outline a targeted therapeutic strategy to treat triple-negative breast cancer - a potential first for the particularly aggressive form of breast cancer.

26 Feb 2019

'Chromosome scanner' that protects against cancer identified

In a new study, researchers from the University of Copenhagen have identified one of the main mechanisms behind the repair of serious damage to the human DNA. A 'scanner' inside the cells decides whether or not so-called flawless DNA repair, which protects against cancer, is launched.

26 Feb 2019

Scientists report new and improved method to detect chemical modifications to DNA

Ludwig Cancer Research scientists report in the current issue of Nature Biotechnology a new and improved method to detect chemical modifications to DNA.

26 Feb 2019

Scientists discover puzzle piece that plays key role in development of epilepsies

When an epileptic seizure occurs in the brain, the nerve cells lose their usual pattern and fire in a very fast rhythm. The cause is a complex interplay of various factors.

25 Feb 2019

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019

Mayo Clinic researchers identify gene that may predict pancreatic cancer risk in diabetic patients

Mayo Clinic researchers have identified a gene called "UCP-1" that may predict the development of pancreatic cancer in people with Type 2 diabetes. Their findings are published in Gastroenterology.

25 Feb 2019

Researchers discover new and rare skeletal disease

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease.

25 Feb 2019

Specific gene variation associated with ADHD could be tied to substance addiction

Some variations in the gene LPHN3 -associated with the attention deficit/hyperactivity disorder (ADHD) in kids and adults- could favor likelihood to smoke, consume alcohol, cannabis and other addictive substances, according to an article published in the journal Translational Psychiatry, from the Nature Publishing Group.

25 Feb 2019

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

As the biomedical field races to develop therapies based on an individual's genetic makeup, a City of Hope scientist and his colleagues found that some commercial cell lines used for countless laboratory studies have mislabeled ancestry when it comes to minorities.

25 Feb 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019

Fat cells exhibit circadian rhythms affecting critical metabolic functions, study finds

Fat cells in the human body have their own internal clocks and exhibit circadian rhythms affecting critical metabolic functions, new research in the journal Scientific Reports, finds.

25 Feb 2019

Using CRISPR to regulate genes in the rat brain

Neuroscientists have used CRISPR/Cas9 genome editing technology to regulate genes in the rat brain. Described in eNeuro, this technique paves the way for researchers to probe genetic influences on brain health and disease in model organisms that more closely resemble human conditions.

From Society for Neuroscience 25 Feb 2019

Genes News and Research

Researchers describe neural mechanisms responsible for local search in hungry worms

Cancer genes’ mutational status influenced by their evolutionary age, regulatory functions

Novel mechanism behind DNA damage control uncovered

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

Researchers outline targeted therapeutic strategy for triple-negative breast cancer

'Chromosome scanner' that protects against cancer identified

Scientists report new and improved method to detect chemical modifications to DNA

Scientists discover puzzle piece that plays key role in development of epilepsies

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Mayo Clinic researchers identify gene that may predict pancreatic cancer risk in diabetic patients

Researchers discover new and rare skeletal disease

Specific gene variation associated with ADHD could be tied to substance addiction

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

Scientists identify cause of devastating pediatric brain disorder

Fat cells exhibit circadian rhythms affecting critical metabolic functions, study finds

Using CRISPR to regulate genes in the rat brain

New form of hereditary osteoporosis identified

Older biologic age associated with increased risk of developing breast cancer

Clinical study shows tolerability and safety of investigational drug in boys with DMD

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