Bacteria News and Research

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Scientists uncover atomic structure of dermcidin

An international team of scientists has discovered how an important natural antibiotic called dermcidin, produced by our skin when we sweat, is a highly efficient tool to fight tuberculosis germs and other dangerous bugs.

22 Feb 2013

Craniofacial surgeons recommend steps to reduce risk of pneumonitis from povidone-iodine

A routine step in preparing for cleft palate surgery in a child led to an unusual-but not unprecedented-case of lung inflammation (pneumonitis), according to a report in the The Journal of Craniofacial Surgery. The journal, edited by Mutaz B. Habal, MD, FRCSC, is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

22 Feb 2013

International nonproprietary name “auriclosene” approved by WHO for NovaBay’s NVC-422

NovaBay® Pharmaceuticals, Inc. (NYSE MKT: NBY), a biotechnology company focused on addressing the large unmet therapeutic needs of the global anti-infective market with first-in-class compounds such as its proprietary Aganocides®, today announced that the World Health Organization (WHO) has approved the international nonproprietary name (INN) “auriclosene” (pronounced awr-rih-CLO-zeen) for the Company’s lead Aganocide® compound NVC-422.

21 Feb 2013

New test for leprosy gives results in less than 10 minutes, New York Times reports

"A simple, fast and inexpensive new test for leprosy offers hope that, even in the poorest countries, victims can be found and cured before they become permanently disabled or disfigured like the shunned lepers of yore," the New York Times reports.

21 Feb 2013

NIAID-funded Phase I trial to evaluate two related candidate vaccines against shigellosis

Researchers have launched an early-stage human clinical trial of two related candidate vaccines to prevent infection with Shigella, bacteria that are a significant cause of diarrheal illness, particularly among children.

21 Feb 2013

Antibody-drug conjugates (ADCs): an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals

ADCs are used for a new type of targeted therapy that consists of a specific anti-cancer antibody or antibody fragment linked to a potent anti-cancer therapeutic.

20 Feb 2013

Mouthrinse use associated with reduced plaque and gingivitis

New research published in the January/February 2013 issue of General Dentistry, the peer-reviewed clinical journal of the Academy of General Dentistry (AGD), indicates that the use of a germ-killing mouthrinse in addition to regular toothbrushing can significantly reduce plaque and gingivitis, more so than brushing alone.

20 Feb 2013

Cholesterol metabolism regulated by bacteria in the small intestine

Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, show that cholesterol metabolism is regulated by bacteria in the small intestine. These findings may be important for the development of new drugs for cardiovascular disease.

19 Feb 2013

Interleukin-10 levels predict otitis media culprit

Research shows that high serum levels of interleukin-10 indicate that the likely cause of acute otitis media is infection with Streptococcus pneumoniae, as opposed to Haemophilus influenzae or Moraxella catarrhalis.

18 Feb 2013

Dietary impacts, health changes and oral pathogen genomic evolution

DNA preserved in calcified bacteria on the teeth of ancient human skeletons has shed light on the health consequences of the evolving diet and behaviour from the Stone Age to the modern day.

18 Feb 2013

Two studies discover new enzyme that acts as a sensor of innate immunity

Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.

16 Feb 2013

Gut microbes can affect severity of kidney disease brought on by melamine poisoning

Microbes present in the gut can affect the severity of kidney disease brought on by melamine poisoning, according to an international study led by Professor Wei Jia at the University of North Carolina in collaboration with the research group of Professor Jeremy Nicholson at Imperial College London.

16 Feb 2013

Natural probiotic supplement can help male mice produce healthier bones

In what could be an early step toward new treatments for people with osteoporosis, scientists at Michigan State University report that a natural probiotic supplement can help male mice produce healthier bones.

16 Feb 2013

Protein test may help identify bacterial COPD exacerbations

Increased serum levels of pancreatic stone protein/regenerating protein may help identify bacteria-related exacerbations of chronic obstructive pulmonary disease, say researchers.

15 Feb 2013

Researchers discover SCANR that helps protect a cell's genes against DNA interlopers

Gene wars rage inside our cells, with invading DNA regularly threatening to subvert our human blueprint. Now, building on Nobel-Prize-winning findings, UC San Francisco researchers have discovered a molecular machine that helps protect a cell's genes against these DNA interlopers.

15 Feb 2013

Improving tuberculosis (TB) diagnosis: an interview with Professor Madhukar Pai, MD, PhD

TB is an infectious disease caused by Mycobacterium tuberculosis. Nearly 9 million people develop TB every year, and TB kills nearly 1.4 million individuals each year. While the incidence of TB has steadily declined in the west, it remains a huge public health problem in many developing countries, with India having the highest burden.

15 Feb 2013

Researchers call for botulism testing in sick and healthy cows

Evidence of Clostridium botulinum and its toxin in milk and udder tissue samples from dairy cows has led German researchers to call for “statistically relevant testing of healthy and sick cows from healthy and affected farms.”

14 Feb 2013

Researchers ESTABLISH efficacy of tedizolid phosphate for skin infections

Results from the phase III ESTABLISH-1 study show that the new antibiotic tedizolid phosphate is noninferior to linezolid for the treatment of acute bacterial and skin structure infections.

14 Feb 2013

Probiotics shows promise in reducing both incidence and severity of necrotizing enterocolitis

"Good" bacteria that live in our intestines have been linked with a variety of health benefits, from fighting disease to preventing obesity. In a new study, Kriston Ganguli of Massachusetts General Hospital for Children and Harvard Medical School and her colleagues have discovered another advantage to these friendly microscopic tenants: Chemicals secreted by good bacteria that typically live in the intestines of babies could reduce the frequency and severity of a common and often-lethal disease of premature infants.

14 Feb 2013

GSK1322322 targets gram-positive bacteria including methicillin-resistant strains of MRSA

An increasing number of bacteria is evolving antibiotic resistance. Much-feared representatives of this steadily growing group include Staphylococci strains. At this point, multi-resistant forms of the bacterium Staphylococcus aureus - the "hospital germ" known commonly by its acronym, MRSA - can only be treated with a select subset of antibiotics as many drugs have simply stopped working. This is precisely why the field of medicine is in desperate need of new treatment options.

14 Feb 2013

Bacteria News and Research

Scientists uncover atomic structure of dermcidin

Craniofacial surgeons recommend steps to reduce risk of pneumonitis from povidone-iodine

International nonproprietary name “auriclosene” approved by WHO for NovaBay’s NVC-422

New test for leprosy gives results in less than 10 minutes, New York Times reports

NIAID-funded Phase I trial to evaluate two related candidate vaccines against shigellosis

Antibody-drug conjugates (ADCs): an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals

Mouthrinse use associated with reduced plaque and gingivitis

Cholesterol metabolism regulated by bacteria in the small intestine

Interleukin-10 levels predict otitis media culprit

Dietary impacts, health changes and oral pathogen genomic evolution

Two studies discover new enzyme that acts as a sensor of innate immunity

Gut microbes can affect severity of kidney disease brought on by melamine poisoning

Natural probiotic supplement can help male mice produce healthier bones

Protein test may help identify bacterial COPD exacerbations

Researchers discover SCANR that helps protect a cell's genes against DNA interlopers

Improving tuberculosis (TB) diagnosis: an interview with Professor Madhukar Pai, MD, PhD

Researchers call for botulism testing in sick and healthy cows

Researchers ESTABLISH efficacy of tedizolid phosphate for skin infections

Probiotics shows promise in reducing both incidence and severity of necrotizing enterocolitis

GSK1322322 targets gram-positive bacteria including methicillin-resistant strains of MRSA

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