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Gut microbiome plays role in immune system regulation, study finds

Scientist have long known that bacteria in the intestines, also known as the microbiome, perform a variety of useful functions for their hosts, such as breaking down dietary fiber in the digestive process and making vitamins K and B7.

19 Dec 2018

Researchers discover promising new compound against Buruli ulcer

Buruli ulcer - one of the most neglected among the NTDs - is a debilitating and stigmatizing disease. Affecting mainly children in West and Central Africa, the chronic disease results in devastating skin lesions and can lead to permanent disfigurement and long-term disabilities.

18 Dec 2018

New compound blocks genetic cause of familial ALS and frontotemporal dementia

Since the ice bucket challenge went viral in 2014, raising awareness and funding for ALS research, scientists have learned much about a disease that disconnects muscles from nerves, leading to muscle atrophy and eventual death. Their ultimate goal is to create medications capable of stopping ALS in its tracks.

18 Dec 2018

Researchers discover how MAPK translocation leads to drug resistance in melanoma

Researchers have discovered that the ER translocation of MAPK leads to drug resistance in melanoma.

18 Dec 2018

Mouse study uncovers how marijuana may damage some adolescent brains

In a study of adolescent mice with a version of a gene linked to serious human mental illnesses, Johns Hopkins Medicine researchers say they have uncovered a possible explanation for how marijuana may damage the brains of some human teens.

18 Dec 2018

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

The CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or "knocking out" a gene in cancer tumors that helps the tumors develop resistance to the drugs.

18 Dec 2018

Parental alcohol use disorder associated with offspring marital outcomes

Children of parents who have alcohol use disorder are more likely to get married under the age of 25, less likely to get married later in life, and more likely to marry a person who has alcohol use disorder themselves, according to a new study by researchers at Virginia Commonwealth University and Lund University in Sweden.

18 Dec 2018

UI study leads to better understanding of signaling capacity between neurons

The fundamental process of information transfer from neuron to neuron occurs through a relay of electrical and chemical signaling at the synapse, the junction between neurons. Electrical signals, called action potentials, cause voltage-gated calcium channels on the presynaptic neuron to open.

18 Dec 2018

Study uncovers novel details about vulnerability of one brain cell to Alzheimer's

Better tactics for detecting, preventing and treating Alzheimer's disease depend on a clearer understanding of cellular-level changes in the minds of patients, and a new study has uncovered novel details about the vulnerability of one type of brain cell.

18 Dec 2018

New $1.6 million NIH grant supports study on a gene vital to circadian rhythms

Circadian rhythms (from the Latin circa diem -- "around a day") based on the Earth's 24-hour rotation have been observed since the fourth century.

18 Dec 2018

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

In biomedical research, plant breeding, and countless other endeavors, geneticists are on the hunt for the specific genes responsible for disease susceptibility, yield, and other traits of interest.

17 Dec 2018

Study finds new strains of hepatitis C virus in sub-Saharan Africa

The largest population study of hepatitis C in Africa has found three new strains of the virus circulating in the general population in sub-Saharan Africa.

17 Dec 2018

New robust method for microscopically profiling tiny single cells

Many of the cell types in our bodies work in obscure ways, that science does not yet fully understand. That also goes for immune cells, which are vital for protecting us against serious diseases.

17 Dec 2018

Researcher conducts study to investigate peripheral blood markers of Alzheimer's disease

Β-amyloid formation, an indicative element of Alzheimer's disease, is a consequence of alternative expression of enzymes involved in the cleavage of amyloid precursor protein, leading to dementia in elderly populations.

17 Dec 2018

New computer model helps predict course of the disease in prostate cancer patients

How does a normal cell turn into a deadly cancer? Seeking an answer to this question, and working alongside other international working groups, researchers from Charité - Universitätsmedizin Berlin examined the tumor genomes of nearly 300 prostate cancer patients.

14 Dec 2018