Cytokine News and Research

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Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

In a recent study posted to the bioRxiv preprint server, researchers demonstrated that the soluble P2X7 receptor is increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. They also showed that the elevated P2X7 receptors correlated with coronavirus disease 2019 (COVID-19) severity.

9 Mar 2022

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Researchers studied how the mRNA-based BNT162b2 COVID-19 vaccine altered the biochemical composition of glial and glioma brain cells in vitro.

8 Mar 2022

Impact of humoral responses in COVID-19

New research discussed the function and impact of humoral immune responses in COVID-19.

7 Mar 2022

Current progress in SARS-CoV-2 vaccine candidates

In a new study, researchers illustrated the current progress and obstacles in COVID-19 vaccine development.

7 Mar 2022

Severity-dependent immune mechanisms in the cerebrospinal fluid and plasma of COVID-19 patients

Researchers determined the immune mechanisms associated with severe neurological manifestations of COVID-19.

7 Mar 2022

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

A new study discusses the outcomes of idiopathic pulmonary fibrosis patients with confirmed SARS-CoV-2 infection.

6 Mar 2022

Diabetes and the mTOR pathway in COVID-19 patients

A new study discusses the possible etiopathogenetic mechanisms associated with diabetes that could enhance the severity of COVID-19.

6 Mar 2022

Combating COVID cytokine storm with targeted nucleic acid therapies

Researchers examine current nucleic acid-based treatments against COVID-19 and their methods of action.

6 Mar 2022

T-cell cytokine and fatty acid work together to trigger a type of cell death

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

4 Mar 2022

Study identifies unique features of MIS-C and how the syndrome gets started in children

A new study by physicians at Columbia University Vagelos College of Physicians and Surgeons has identified unique features of MIS-C, a rare but potentially deadly complication of COVID in children, that suggest how the syndrome gets started.

4 Mar 2022

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

A new study published on the bioRxiv* preprint server has evaluated bacterial susceptibility during SARS-CoV-2 infection.

3 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

COVID-19 severity is correlated with body composition

In a recent study posted to the medRxiv* preprint server, researchers assessed the effect of changes in the abdominal well-being and physique on coronavirus disease 2019 (COVID-19) severity using magnetic resonance imaging (MRI).

28 Feb 2022

Scientists discover an innate form of immunological memory in the intestine

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa.

28 Feb 2022

Molecular insights on the possible connection of SARS-CoV-2 and nicotinic acetylcholine receptors

A recent study assessed the mechanism by which SARS-CoV-2 Omicron and Alpha VOCs inhibit the SARS-CoV-2 spike protein and mitigate the risk of a multisystem inflammatory syndrome in children.

28 Feb 2022

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Researchers evaluated the pathogenicity and replication potential of SARS-CoV-2 VOC Omicron lineage, BA.2 in immunocompetent mice and hamsters.

28 Feb 2022

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Researchers characterized humoral and SARS-CoV-2 S-specific T cell responses in IBD patients who received two-dose mRNA-based COVID-19 vaccination series.

25 Feb 2022

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection.

24 Feb 2022

Melatonin as a safe and potentially life-saving treatment for COVID-19

A new study discusses the possible role of melatonin, an antioxidant and anti-inflammatory agent, in treating COVID-19.

24 Feb 2022

SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Researchers demonstrated that the SARS-CoV-2 viroporins precipitate cytokine storm via the alteration of mitochondrial physiology in severe COVID-19.

24 Feb 2022

Cytokine News and Research

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Impact of humoral responses in COVID-19

Current progress in SARS-CoV-2 vaccine candidates

Severity-dependent immune mechanisms in the cerebrospinal fluid and plasma of COVID-19 patients

How does COVID-19 affect patients with idiopathic pulmonary fibrosis?

Diabetes and the mTOR pathway in COVID-19 patients

Combating COVID cytokine storm with targeted nucleic acid therapies

T-cell cytokine and fatty acid work together to trigger a type of cell death

Study identifies unique features of MIS-C and how the syndrome gets started in children

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

COVID-19 severity is correlated with body composition

Scientists discover an innate form of immunological memory in the intestine

Molecular insights on the possible connection of SARS-CoV-2 and nicotinic acetylcholine receptors

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

Melatonin as a safe and potentially life-saving treatment for COVID-19

SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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