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Checkpoint inhibitors may not be effective lymphoma treatment when CAR T fails

For 30% to 40% of lymphoma patients who receive CAR T therapy, the treatment is a godsend.

25 Apr 2023

Previously unknown mechanisms may lead to new approaches to fight viral infections

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

25 Apr 2023

Researchers uncover the molecular basis for making long-term memories

Helping your mother make pancakes when you were three…riding your bike without training wheels…your first romantic kiss: How do we retain vivid memories of long-ago events? As described in a paper published online on April 25 in Neuron, researchers at Albert Einstein College of Medicine have found the explanation.

25 Apr 2023

Highly activatable Raman probes detect multiple enzyme activities in heterogeneous biological tissues

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation.

25 Apr 2023

Columbia University establishes the SNF Center for Precision Psychiatry & Mental Health with $75 million grant

Columbia University today announced the establishment of the Stavros Niarchos Foundation (SNF) Center for Precision Psychiatry & Mental Health at Columbia University.

25 Apr 2023

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

A new approach to chimeric antigen receptor T-cell (CAR T) therapy has shown great promise against small cell lung cancer (SCLC) in a preclinical study.

25 Apr 2023

Study finds biomarker pattern in children with COVID 19-linked multisystem inflammatory syndrome

Children with multisystem inflammatory syndrome (MIS-C) — a rare condition linked with the virus that causes COVID-19 — have biochemical indicators of cell injury and cell death that are distinct from other children with COVID-19, according to a study funded by the National Institutes of Health.

25 Apr 2023

T cell-mediated recognition of conserved bacterial epitope generates broad immunity

Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity.

25 Apr 2023

A new platform for testing cancer drug toxicity

For people with cancer, chemotherapy saves lives, but for some patients, the treatment comes with a side effect—heart damage.

25 Apr 2023

Study establishes a new method for examining relationships between neuron type and function

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between "test tube" data about neurons and the function of those cells in the living brain.

25 Apr 2023

Rhythmic brain activity key to temporarily maintaining memories, research shows

New research shows that rhythmic brain activity is key to temporarily maintaining important information in memory.

25 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

The potential anti-cancer and antioxidant properties of walnuts

Researchers reviewed current literature to examine walnuts' potential antioxidant and anti-cancer properties.

25 Apr 2023

Does oral exposure to cannabidiol (CBD) have toxic implications?

Researchers reviewed the implications of oral exposure to cannabidiol (CBD).

25 Apr 2023

Understanding how consumption of beef vs. plant-based burgers alters the lipemic response and gut microbiota

Researchers reviewed the differences in the digestive process between beef and plant-based burgers from ingestion to excretion.

25 Apr 2023

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Research investigates the susceptibility of seven bat species to SARS-CoV-2 by expressing their ACE2 receptor in a non-permissive avian cell line. The study found that all seven bat species were susceptible to SARS-CoV-2, but the level of virus replication differed between bat species and virus variants.

24 Apr 2023

Novel gel offers hope for patients with glioblastoma

Medication delivered by a novel gel cured 100% of mice with an aggressive brain cancer, a striking result that offers new hope for patients diagnosed with glioblastoma, one of the deadliest and most common brain tumors in humans.

24 Apr 2023

New and efficient technique for rapid antibiotic susceptibility testing using optical microscopy

Researchers at EPFL and Vrije Universiteit Brussel have developed a novel and highly efficient method for rapid antibiotic susceptibility testing using optical microscopy.

24 Apr 2023

Exploring metabolic compatibility as a possible limiting factor to prokayrotic endosymbioses

"One of the great mysteries of biology," says Eric Libby, former SFI Postdoctoral Fellow, now an associate professor at the Integrated Science Lab (IceLab), Umeå University in Sweden, "is eukaryogenesis, or how eukaryotes arose." Scientists consider this to be a period of major evolutionary transition, critical to our understanding of the history and evolution of life on Earth.

24 Apr 2023

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer's disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists.

24 Apr 2023

Cell News and Research

Checkpoint inhibitors may not be effective lymphoma treatment when CAR T fails

Previously unknown mechanisms may lead to new approaches to fight viral infections

Researchers uncover the molecular basis for making long-term memories

Highly activatable Raman probes detect multiple enzyme activities in heterogeneous biological tissues

Columbia University establishes the SNF Center for Precision Psychiatry & Mental Health with $75 million grant

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

Study finds biomarker pattern in children with COVID 19-linked multisystem inflammatory syndrome

T cell-mediated recognition of conserved bacterial epitope generates broad immunity

A new platform for testing cancer drug toxicity

Study establishes a new method for examining relationships between neuron type and function

Rhythmic brain activity key to temporarily maintaining memories, research shows

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

The potential anti-cancer and antioxidant properties of walnuts

Does oral exposure to cannabidiol (CBD) have toxic implications?

Understanding how consumption of beef vs. plant-based burgers alters the lipemic response and gut microbiota

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Novel gel offers hope for patients with glioblastoma

New and efficient technique for rapid antibiotic susceptibility testing using optical microscopy

Exploring metabolic compatibility as a possible limiting factor to prokayrotic endosymbioses

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

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