Genes News and Research

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Newly designed mice emulate severe form of kidney damage in humans with diabetes

Scientists led by Duke-NUS Medical School have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy.

9 Nov 2018

Study finds that thymus plays key role during normal pregnancy

The immune system of a pregnant woman is altered during pregnancy, but not in the way previously believed, according to results from a study at Linköping University, Sweden.

9 Nov 2018

ChromDesign project trains budding scientists in 3D architecture of genome

How does the three-dimensional architecture of our genes affect the differentiation of cells and development of diseases? This is the question behind the European Innovation Training Network "ChromDesign- Chromatin and Design".

8 Nov 2018

Salk researchers solve genetic 'whodunnit' for cancer gene

Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, Salk Institute researchers have solved the long-standing mystery around why AMPK can both hinder and help cancer.

8 Nov 2018

Monash researchers provide insight into intricate peptide changes affecting immune system

Human leukocyte antigen molecules are a group of proteins that help the immune system identify foreign invaders such as viruses and bacteria and which impact a wide variety of clinical outcomes including infection and cancer.

8 Nov 2018

CWRH/UH researcher receives grant to study role of KLF2 factor in vascular-related disorders

Transcription factors are proteins that determine whether specific genes are transcribed or not by binding to DNA. In other words, they help turn genes "on" or "off."

8 Nov 2018

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

A new study by Washington State University researchers suggests that a protein called CDK2 plays a critical role in heart damage caused by doxorubicin, a commonly used chemotherapy drug.

8 Nov 2018

New open source decision support tool could help clinicians chose chemotherapy drugs

The selection of a first-line chemotherapy drug to treat many types of cancer is often a clear-cut decision governed by standard-of-care protocols, but what drug should be used next if the first one fails?

8 Nov 2018

New discovery confirms central importance of PINK1-Parkin pathway in Parkinson's patients

Researchers at the Faculty of Medicine, University of Helsinki, make an unexpected and vital contribution to an international collaborative effort in Parkinson's disease research.

7 Nov 2018

UTSA research could help address genetically based challenges with male fertility

Millions of couples who have trouble conceiving may get relief from new research led by scientists at The University of Texas at San Antonio.

7 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Tracking down microRNA candidates linked to disease

What started as Ninad Oak's side project turned out into something much larger, his doctorate thesis. "The project started as my qualifying exam that I proposed at the end of my first year of graduate school," said Oak, a graduate student in molecular and human genetics in Dr. Sharon E. Plon's lab. "This was an off topic qualifying exam at the time, meaning the lab had not worked on this topic before."

7 Nov 2018

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong, in collaboration with scientists from Tsinghua University in China, The Rockefeller University, and The University of Texas MD Anderson Cancer Center in the United States, developed the first chemical inhibitors against a novel therapeutic target for treatment of acute myeloid leukemia, a fast-growing cancer of bone marrow and blood cells.

7 Nov 2018

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Scientists are making strides in developing liquid biopsies for brain tumors by detecting tumor DNA in the fluid from around the brain and spine.

7 Nov 2018

Experts study antibiotic resistance in recycled water

Bacteria that become resistant to antibiotics lead to an estimated 23,000 deaths and 2 million illnesses per year in the U.S. The Centers for Disease Control is launching an expansive effort to study various facets of the growing threat by funding researchers across the nation, including two prominent water experts at Virginia Tech.

7 Nov 2018

Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

Treating pre-cancerous stem cells at an early stage could be key to preventing bowel cancer in people born with a very high risk of the disease, according to a study in mice presented at the 2018 NCRI Cancer Conference.

7 Nov 2018

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

The U.S. Department of Defense has granted the "Impact Award" to explore new therapeutic options against advanced prostate cancer - scientifically known as castration-resistant or hormone therapy resistant prostate cancer- to a multidisciplinary team of researchers made up of the Prostate Cancer Clinical Research Unit of the Spanish National Cancer Research Center, led by David Olmos, the Prostate Cancer Translational Research Group of the Vall d'Hebron Institute of Oncology, led by Joaquín Mateo, and the Genetics and Solid Tumors Laboratory of the University of Washington, led by Colin Pritchard.

7 Nov 2018

Genes News and Research

Newly designed mice emulate severe form of kidney damage in humans with diabetes

Study finds that thymus plays key role during normal pregnancy

ChromDesign project trains budding scientists in 3D architecture of genome

Salk researchers solve genetic 'whodunnit' for cancer gene

Monash researchers provide insight into intricate peptide changes affecting immune system

CWRH/UH researcher receives grant to study role of KLF2 factor in vascular-related disorders

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

New open source decision support tool could help clinicians chose chemotherapy drugs

New discovery confirms central importance of PINK1-Parkin pathway in Parkinson's patients

UTSA research could help address genetically based challenges with male fertility

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Tracking down microRNA candidates linked to disease

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Experts study antibiotic resistance in recycled water

Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

Scientists discover new details about UHRF1 protein

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

Geneticists decipher new gene responsible for rare form of hair loss

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