Clinical Trial News and Research

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Women with Alzheimer's show reduced levels of healthy unsaturated fats

Omega fatty acids could protect against Alzheimer's disease in women, new research has found.

20 Aug 2025

Seven blood metabolites associated with excessive daytime sleepiness

Mass General Brigham researchers identified seven molecules in the blood linked to excessive daytime sleepiness, including factors related to diet and hormones.

20 Aug 2025

International study tests promising vaccine against 21 strains of pneumococcus

A new vaccine for pneumococcal disease will be tested under an international trial aiming to provide greater protection to babies against the common infection that causes pneumonia, sinusitis and meningitis.

19 Aug 2025

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Texas Children's is pleased to announce that a three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency.

19 Aug 2025

Tenofovir amibufenamide shows efficacy in chronic hepatitis B patients with normal ALT

Chronic hepatitis B virus (HBV)-infected patients may exhibit liver fibrosis and other pathological changes despite normal alanine aminotransferase (ALT).

19 Aug 2025

FAST walk shows promise in improving gait for chronic stroke patients

Stroke remains one of the leading causes of long-term disability worldwide, affecting millions each year.

19 Aug 2025

Community-driven ADHD initiative leads to better outcomes for children

Innovative intervention delivered by trained community health workers – meaning nonclinical personnel with deep knowledge of the community – increased treatment utilization among participating families with children who have ADHD, according to a pilot study published in the Journal of Attention Disorders.

18 Aug 2025

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Patients in a Phase I/II clinical trial conducted by UMass Chan Medical School of a dual vector gene therapy for GM2 gangliosidosis, which includes Tay-Sachs and Sandhoff diseases, exhibited a biochemical correction of the disease with minimal adverse reactions.

18 Aug 2025

Fasting does not have the same effect on all body types, study suggests

While fasting has become a popular trend, particularly for people who hope to lose weight, new UBC Okanagan research suggests fasting does not have the same effect on all body types.

18 Aug 2025

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

18 Aug 2025

New AAV gene therapy reverses age-related macular degeneration

Neovascular age-related macular degeneration (nAMD) is a progressive eye disease characterized by choroidal neovascularization and subretinal hemorrhage and exudation, leading to vision impairment. Current first-line treatment for nAMD are anti-VEGF agents, which has shown promising therapeutics outcomes.

18 Aug 2025

UC San Diego's ACTRI wins $80 million Clinical and Translational Science Award

The University of California San Diego's Altman Clinical and Translational Research Institute (ACTRI) has received a seven-year, $80 million Clinical and Translational Science Award (CTSA) from the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health.

14 Aug 2025

Smartphone app doubles quit rates among low-income smokers

While smoking rates in the United States have substantially declined over the past six decades, smoking remains high among people with low incomes, leading to health disparities.

14 Aug 2025

Engineered CD40 antibody shrinks tumors and induces remission

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise-and induced great disappointment.

14 Aug 2025

HonorHealth taps longevity authority Nicholas J. Schork to lead new research division

Nicholas J. Schork, Ph.D., an international authority on human longevity and health maintenance, has joined HonorHealth Research Institute as Research Director of Longevity, Prevention and Interception.

14 Aug 2025

Arginine dentifrices reduce dental caries in children with active caries

The International Association for Dental, Oral, and Craniofacial Research (IADR) and the American Association for Dental, Oral, and Craniofacial Research (AADOCR) have announced the publication of a new study in JDR Clinical & Translational Research that demonstrates that arginine dentifrices reduce dental caries in children with active caries as much as, or more than, a sodium fluoride dentifrice, depending on the arginine concentration.

13 Aug 2025

Early use of risdiplam in newborns with SMA shows improvements in motor development

Spinal muscular atrophy (SMA) is a rare genetic condition that causes progressive muscle weakness, which, when untreated, prevents infants with the most severe form from gaining motor development - never gaining the ability to sit - and typically leads to death before 2 years of age.

13 Aug 2025

Griffith University launches groundbreaking treatment trial for spinal cord injury

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Clinical Trial News and Research

Women with Alzheimer's show reduced levels of healthy unsaturated fats

Seven blood metabolites associated with excessive daytime sleepiness

International study tests promising vaccine against 21 strains of pneumococcus

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Tenofovir amibufenamide shows efficacy in chronic hepatitis B patients with normal ALT

FAST walk shows promise in improving gait for chronic stroke patients

Community-driven ADHD initiative leads to better outcomes for children

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Fasting does not have the same effect on all body types, study suggests

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

New AAV gene therapy reverses age-related macular degeneration

UC San Diego's ACTRI wins $80 million Clinical and Translational Science Award

Smartphone app doubles quit rates among low-income smokers

Engineered CD40 antibody shrinks tumors and induces remission

HonorHealth taps longevity authority Nicholas J. Schork to lead new research division

Arginine dentifrices reduce dental caries in children with active caries

Early use of risdiplam in newborns with SMA shows improvements in motor development

Griffith University launches groundbreaking treatment trial for spinal cord injury

New drug-releasing system eliminates tumors in 82% of high-risk bladder cancer patients

Conch shell blowing lowers apnea events during REM sleep

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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