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Scientists identify molecule that could be targeted to prevent vision loss in diabetics and preterm infants

Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic mice.

23 Mar 2017

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Building on earlier work in designing chimeric human-simian immunodeficiency viruses (SHIVs) that serve as a model of HIV infection of humans, George M. Shaw, MD, PhD, a professor of Hematology/Oncology and Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has received $16.3 million over five years from the National Institute of Allergy and Infectious Diseases to develop a long-sought-after HIV vaccine.

22 Mar 2017

Rapid weight gain during infancy could lead to obesity in adulthood

Rapid weight gain in an infant's first six months of life is a risk factor for child- and adulthood obesity, according to researchers.

22 Mar 2017

Study identifies urinary biomarker that may help monitor progression of ALS

A study in Neurology suggests that analyzing levels of the protein p75ECD in urine samples from people with amyotrophic lateral sclerosis (ALS) may help monitor disease progression as well as determine the effectiveness of therapies.

22 Mar 2017

UC researchers advocate ‘precision medicine’ approach to studying and treating Parkinson's disease

Two landmark publications with one or more co-authors from the University of Cincinnati Gardner Neuroscience Institute outline a transformative approach to defining, studying and treating Parkinson's disease.

22 Mar 2017

Study shows how long-term, weight-bearing exercises trigger bone formation in men

Osteoporosis affects more than 200 million people worldwide and is a serious public health concern, according to the National Osteoporosis Foundation.

22 Mar 2017

Machine learning helps researchers uncover cellular control networks

The flow of information between cells in our bodies is exceedingly complex: sensing, signaling, and influencing each other in a constant flow of microscopic engagements. These interactions are critical for life, and when they go awry can lead to the illness and injury.

22 Mar 2017

RUB researchers identify new rare muscle disorder

A new rare muscle disorder has been identified by researchers at Ruhr-Universität Bochum. This hereditary disease is caused by a defect in the BICD2 gene that manifests itself in altered cellular transport processes in skeletal muscle cells.

22 Mar 2017

PHD2-knockdown overcomes breast cancer cell death in response to glucose starvation

B55α is one of the regulatory subunits of the PP2A phosphatase. This phosphatases has been associated to the control of many biological functions but the multiplicity of complexes that can be formed by the combination of different subunits renders this protein hard in its understanding.

22 Mar 2017

Study shows how zinc regulates storage and release of neurotransmitters

Zinc is a vital micronutrient involved in many cellular processes: For example, in learning and memory processes, it plays a role that is not yet understood. By using nanoelectrochemical measurements, Swedish researchers have made progress toward understanding by demonstrating that zinc influences the release of messenger molecules.

22 Mar 2017

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Researchers at Baylor College of Medicine, Texas Children's Hospital and Rice University have uncovered a gene mutation that may provide answers to unexplained female infertility. The study appears in Scientific Reports, a member of the Nature family of journals.

22 Mar 2017

Changes in the vascular system could play role in initiating Alzheimer’s disease

As the average age of Americans increases, so too does the problem of Alzheimer's, one of the world's most common neurological diseases. In recent years, scientists have explored many new approaches to clear the plaques and tangles in the brain that characterize the condition, but the new drugs have largely turned out to be disappointing.

22 Mar 2017

New Danish research provides structural knowledge of DNA repair complex

New Danish research provides mechanistic insight into how DNA is monitored and repaired if damage occurs. The results may eventually help to improve the treatment of certain types of cancer, as the DNA repair complex provides a mechanism for cancer cells to resist chemotherapy.

21 Mar 2017

New research shows how to prevent prions from growing into deadly diseases

Prion diseases are scary, incurable and fatal. They first gained notoriety when cows became infected by prion proteins and, in turn, infected people. Fervor surrounding mad cow disease resulted in the U.S. banning imports of beef from the European Union for 15 years.

21 Mar 2017

Simple blood test may soon eliminate need for invasive procedures to detect, monitor cancer

Doctors may soon be able to detect and monitor a patient's cancer with a simple blood test, reducing or eliminating the need for more invasive procedures, according to Purdue University research.

21 Mar 2017

Study: Treatment window for Fragile X syndrome likely remains open into maturity after childhood

Brain samples from humans show that the treatment window for Fragile X syndrome likely remains open well into maturity after childhood, when previous tests with mice indicated it might close, according to a new Drexel University-led study.

21 Mar 2017

Research findings suggest potential strategies to combat IBMPFD and other degenerative diseases

UCLA researchers have discovered the molecular basis of, and identified potential treatment for, an incurable disease known as inclusion body myopathy, Paget disease with frontotemporal dementia, or IBMPFD.

21 Mar 2017

Penn scientists discover method that appears to provide early warning of transplant rejection

Approximately 30,000 organ transplants occur in the United States each year. However, between 20 and 50 percent—depending on the organ type—of the transplanted organs fail within five years, most often because the recipient's immune system attacks, or "rejects," the donated organ.

21 Mar 2017

Tsimane indigenous South Americans have lowest prevalence of coronary atherosclerosis of any population yet studied

The Tsimane people – a forager-horticulturalist population of the Bolivian Amazon – have the lowest reported levels of vascular ageing for any population, with coronary atherosclerosis (hardening of the arteries) being five times less common than in the US, according to a study published in The Lancet and being presented at the American College of Cardiology conference.

21 Mar 2017

AXT introduces super-resolution fluorescence microscope capable of single molecule imaging in Australia and NZ

AXT are proud to announce that they have recently been appointed the exclusive Australian and New Zealand distributor for Oxford Nanoimaging (ONI). ONI is a UK-based company that has commercialised the “Nanoimager” a revolutionary super-resolution fluorescence microscope capable of single molecule imaging.

From AXT Pty Ltd 21 Mar 2017

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G Protein News and Research

Scientists identify molecule that could be targeted to prevent vision loss in diabetics and preterm infants

Penn researcher receives $16.3 million NIAID grant to develop long-sought-after HIV vaccine

Rapid weight gain during infancy could lead to obesity in adulthood

Study identifies urinary biomarker that may help monitor progression of ALS

UC researchers advocate ‘precision medicine’ approach to studying and treating Parkinson's disease

Study shows how long-term, weight-bearing exercises trigger bone formation in men

Machine learning helps researchers uncover cellular control networks

RUB researchers identify new rare muscle disorder

PHD2-knockdown overcomes breast cancer cell death in response to glucose starvation

Study shows how zinc regulates storage and release of neurotransmitters

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Changes in the vascular system could play role in initiating Alzheimer’s disease

New Danish research provides structural knowledge of DNA repair complex

New research shows how to prevent prions from growing into deadly diseases

Simple blood test may soon eliminate need for invasive procedures to detect, monitor cancer

Study: Treatment window for Fragile X syndrome likely remains open into maturity after childhood

Research findings suggest potential strategies to combat IBMPFD and other degenerative diseases

Penn scientists discover method that appears to provide early warning of transplant rejection

Tsimane indigenous South Americans have lowest prevalence of coronary atherosclerosis of any population yet studied

AXT introduces super-resolution fluorescence microscope capable of single molecule imaging in Australia and NZ

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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