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Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Researchers developed a novel intranasal vaccine candidate for coronavirus disease 2019 (COVID-19).

14 Apr 2023

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled - a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease.

13 Apr 2023

B cells use mechanical force to pull antigen molecules off other cells

Most cells evolve slowly, accumulating incremental changes that better suit their environments. Immune cells, because they must adapt rapidly to counter new threats, evolve much more quickly.

13 Apr 2023

New clinical RNA sequencing platform helps carve a path for Precision Child Health

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver individualized care for every patient.

13 Apr 2023

Researchers develop new approach for studying HBV in the lab

Hepatitis C and hepatitis B viruses both attack the liver, eventually causing deadly cirrhosis or cancer. But while antivirals can cure 95 percent of HCV infections, its cousin HBV has long eluded effective therapeutics.

13 Apr 2023

Study uncovers hallmarks to improving pancreatic cancer therapy

Scientists from the University of California, Irvine, the University of Michigan and the University of Texas MD Anderson Cancer Center have made a significant contribution to the field of pancreatic cancer research.

13 Apr 2023

New AI tool accurately predicts aggressiveness of colorectal cancer

A new artificial intelligence model designed by researchers at Harvard Medical School and National Cheng Kung University in Taiwan could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer, the second deadliest cancer worldwide.

13 Apr 2023

Researchers show how the EBV virus exploits genomic weaknesses to cause cancer

The Epstein-Barr virus (EBV) is easily spread through bodily fluids, primarily saliva, such as kissing, shared drinks or using the same eating utensils.

13 Apr 2023

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

The current COVID-19 vaccines are designed to trigger an antibody response to the SARS-CoV-2 spike protein, which is vulnerable to mutations that could make the vaccine less effective over time.

13 Apr 2023

Using an implantable nanofluidic device to tame pancreatic cancer

Houston Methodist nanomedicine researchers have found a way to tame pancreatic cancer - one of the most aggressive and difficult to treat cancers - by delivering immunotherapy directly into the tumor with a device that is smaller than a grain of rice.

13 Apr 2023

Curtin researchers identify the genetic signature of pre-malignant liver cells

Researchers at Curtin University have identified the genetic signature of pre-malignant liver cells, offering potentially significant implications for the almost 3,000 Australians diagnosed with the deadly cancer each year.

13 Apr 2023

Genomic study reveals Babesia duncani's pathogenicity and virulence

'Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between May and October by a tick.

13 Apr 2023

Changes to tumor DNA can help predict cancer's next move

Knowing whether a tumor might grow or spread to other parts of a patient’s body could be key to survival – and now scientists are one step closer to unlocking the ability to predict just that.

13 Apr 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

New treatment pathway identified for patients with idiopathic nephrotic syndrome

With funding from charity Kidney Research UK, Dr Carl May from Bristol Medical School and his team have identified a new treatment pathway for patients with non-genetic (idiopathic) nephrotic syndrome (INS), targeting a still unknown factor that causes the progression towards kidney failure.

13 Apr 2023

MHRA research evaluates two different approaches to cancer therapies

The report 'Antibody conjugates for targeted delivery of Toll-like receptor 9 agonist to the tumor tissue', published in the PLOS ONE journal, highlights MHRA research which showed that genetic engineering of antibodies used to activate and support the immune system against cancer leads to improvements in their reliability and effectiveness.

13 Apr 2023

New tool provides insight into the developmental history of certain immune cells

A new tool that can uncover the developmental history of certain immune cells is now freely available worldwide. The tool provides insights into the stages that immune cells go through in a healthy individual and how this can be impacted in disease.

13 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

Early-life gut microbial dysbiosis exacerbates colitis

A recent Research journal study investigated the role of microbiota linked to the anaerobic plasmalogen biosynthetic pathway in establishing intestinal homeostasis. The study hypothesized that the presence of pls [PlsA/R]-positive bacterial species and plasmalogen bestow valuable intestine homeostasis in early life.

13 Apr 2023

Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018

A recent article identifies the encephalitogenic viruses registered in Brazil over the past six decades.

12 Apr 2023

Cell News and Research

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

B cells use mechanical force to pull antigen molecules off other cells

New clinical RNA sequencing platform helps carve a path for Precision Child Health

Researchers develop new approach for studying HBV in the lab

Study uncovers hallmarks to improving pancreatic cancer therapy

New AI tool accurately predicts aggressiveness of colorectal cancer

Researchers show how the EBV virus exploits genomic weaknesses to cause cancer

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

Using an implantable nanofluidic device to tame pancreatic cancer

Curtin researchers identify the genetic signature of pre-malignant liver cells

Genomic study reveals Babesia duncani's pathogenicity and virulence

Changes to tumor DNA can help predict cancer's next move

Research reveals molecular features of rare mtDNA mutations

New treatment pathway identified for patients with idiopathic nephrotic syndrome

MHRA research evaluates two different approaches to cancer therapies

New tool provides insight into the developmental history of certain immune cells

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

Early-life gut microbial dysbiosis exacerbates colitis

Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018

How to optimize your cell line development eBook

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Evaluating new approaches for rare disease genomics

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