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UTHealth scientists discover powerful predictors of congestive heart failure

A team of scientists at The University of Texas Health Science Center at Houston and Baylor College of Medicine, led by Eric Boerwinkle, Ph.D., Richard Gibbs, Ph.D., and Bing Yu, Ph.D., have identified powerful predictors of congestive heart failure, a major cause of hospitalization and death in the United States.

31 Aug 2016

Genes may influence how people feel about their weight, study shows

Do you feel overweight, about right, or too skinny? Your answer to that question may be tied to genes you inherited from your parents, especially if you are a female, according to a new study led by the University of Colorado Boulder.

31 Aug 2016

Study collects data on 30-day mortality for breast, lung cancer patients after SACT to improve patient care

For the first time, national data on 30-day mortality for patients with breast and lung cancer treated with chemotherapy have been collected and analysed in order to help clinical teams review and improve patient care, and identify groups of patients who may have additional needs.

31 Aug 2016

Breastfeeding for longer than 6 months can lower breast cancer mortality risk

A new study of women 20 years after undergoing surgery for primary breast cancer shows that breastfeeding for longer than 6 months is associated with a better survival rate.

31 Aug 2016

Simple steps can improve survival of sepsis patients

Sepsis, commonly called blood poisoning, is a common affliction that can affect people of all ages. A series of simple measures tested at a Norwegian hospital can make a difference in successfully treating sepsis.

31 Aug 2016

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

In an effort to determine if stem cell therapy can prevent or improve a condition called "diabetic foot" caused by poor blood flow in patients with diabetes, a team of researchers in China has found that transplanting human placenta-derived mesenchymal stem cells (MSCs) into rats modeled with diabetes can affect blood vessel growth, potentially improving blood flow and preventing critical limb ischemia (CLI), a condition that results in diabetic foot and frequently leads to amputation.

30 Aug 2016

Study urges caution when using BP-lowering treatment in patients with coronary artery disease

Caution has been urged in the use of blood pressure lowering treatment for heart disease patients after a study in more than 22 000 patients with coronary artery disease found that too low blood pressure was associated with worse outcomes. The analysis from the CLARIFY registry is presented today at ESC Congress and published in The Lancet.

30 Aug 2016

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

Previous studies at the University of Colorado Cancer Center show that the experimental drug AMPI-109 potently kills triple-negative breast cancer cells.

30 Aug 2016

Selective manipulation of enzyme can stop cancer cachexia

Healthy fat tissue is essential for extended survival in the event of tumor-induced wasting syndrome (cachexia). In Nature Medicine, researchers at Helmholtz Zentrum München show that selective manipulation of an enzyme can stop unwanted metabolic processes.

30 Aug 2016

New generation drug eluting stents show lower efficacy than contemporary BMS, study shows

New generation drug eluting stents (new DES) did not outshine contemporary bare metal stents (BMS) as they were expected to, in a surprise finding of the largest randomized stent trial to date.

30 Aug 2016

OPTICARE study shows year-long CR program makes heart patients happier, healthier and active

Enhanced cardiac rehabilitation (CR) programs that include a year of group or personal lifestyle and fitness coaching did not improve cardiovascular risk scores more than a standard 3-month program in patients recovering from a heart attack.

30 Aug 2016

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Since the isolation of morphine from opium in the 19th century, scientists have hoped to find a potent opioid analgesic that isn't addictive and doesn't cause respiratory arrest with increased doses.

30 Aug 2016

Study finds tight glycemic control provides no impact on patient-important microvascular outcomes

The glucocentric focus on lowering blood sugar in Type 2 diabetes may have short-circuited development of new diabetes therapies, according to a new paper published by Mayo Clinic researchers in the journal Circulation: Cardiovascular Quality and Outcomes.

29 Aug 2016

ESC-ACCA launches first European standards for management of heart attack patients

The first European standards for the management of heart attack patients are launched today by the European Society of Cardiology-Acute Cardiac Care Association.

29 Aug 2016

Active strategy of detecting and treating asymptomatic MSAD results in no clinical benefit

In patients with high-risk coronary artery disease (CAD), an active strategy of detecting and treating asymptomatic multisite artery disease (MSAD) combined with intensive medical therapy did not improve 2-year outcomes compared to a more traditional approach of managing only symptomatic coronary and extracoronary lesions, new research shows.

29 Aug 2016

Remote monitoring shows no improvement in outcomes for heart failure patients with CIEDs

For heart failure patients with cardiac implantable electronic devices (CIEDs), remote monitoring of their condition does not improve outcomes compared to usual care, according to Hot Line results presented at ESC Congress 2016 and to be simultaneously published in JAMA.

29 Aug 2016

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

A single dose of mesenchymal stem cells delivered intravenously to patients with chronic non-ischemic cardiomyopathy was not associated with significant cardiac structural or functional improvements, but did result in several clinically relevant benefits, according to results from a phase II-a randomized trial.

29 Aug 2016

Mortality News and Research

UTHealth scientists discover powerful predictors of congestive heart failure

Genes may influence how people feel about their weight, study shows

Study collects data on 30-day mortality for breast, lung cancer patients after SACT to improve patient care

Breastfeeding for longer than 6 months can lower breast cancer mortality risk

Simple steps can improve survival of sepsis patients

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

Study urges caution when using BP-lowering treatment in patients with coronary artery disease

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

Selective manipulation of enzyme can stop cancer cachexia

New generation drug eluting stents show lower efficacy than contemporary BMS, study shows

OPTICARE study shows year-long CR program makes heart patients happier, healthier and active

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Study finds tight glycemic control provides no impact on patient-important microvascular outcomes

ESC-ACCA launches first European standards for management of heart attack patients

Active strategy of detecting and treating asymptomatic MSAD results in no clinical benefit

Remote monitoring shows no improvement in outcomes for heart failure patients with CIEDs

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

Large cardiopoietic regenerative therapy trial for patients with congestive heart failure reveals new insights

Each NHS hospital admission linked to 2% increased risk of death for heart failure patients

Mediterranean Diet linked to mortality risk reduction in patients with cardiovascular disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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