Genes News and Research

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Dysfunction of single gene leads to miscarriages

A single gene of the mother plays such a crucial role in the development of the placenta that its dysfunction leads to miscarriages.

19 Oct 2018

Newly discovered compound shows potential for treating Parkinson's disease

A joint research group centered around Professor Hideyuki Okano and Associate Professor Jun Kohyama, Department of Physiology of the Keio University School of Medicine, together with a research group of Eisai Co., Ltd. has identified a compound that has the potential to be a treatment for Parkinson's disease by using dopaminergic neurons differentiated from induced pluripotent stem (iPS) cells from patients with familial Parkinson's disease.

19 Oct 2018

Sweat bees are ideal for studying the genes underlying social behavior

Those pesky bees that come buzzing around on a muggy summer day are helping researchers reveal the genes responsible for social behaviors.

19 Oct 2018

LJI and UC San Diego awarded $ 4.5 million as part of NCI's Cancer Moonshot initiative

Researchers at La Jolla Institute for Immunology and UC San Diego have been awarded $ 4.5 million as part of the National Cancer Institute's Cancer Moonshot initiative.

19 Oct 2018

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

UT Southwestern biochemist Dr. Zhijian "James" Chen today was named winner of the prestigious 2019 Breakthrough Prize in Life Sciences for his discovery of the cGAS enzyme that launches the body's immune defense against infections and cancers.

19 Oct 2018

Gene sequencing reveals crucial molecular aspects of Trypanosoma brucei

Trypanosoma brucei, which causes sleeping sickness, evades the immune system by repeatedly altering the structure of its surface coat. Sequencing of its genome and studies of its 3D genome architecture have now revealed crucial molecular aspects of this strategy.

19 Oct 2018

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic code with the cognate amino acid, which are the building blocks of proteins.

19 Oct 2018

Father’s exposure to nicotine may cause cognitive deficits in descendants

A father’s exposure to nicotine may cause cognitive deficits in his children and even grandchildren, according to a study in mice publishing on October 16 in the open-access journal PLOS Biology by Pradeep Bhide of Florida State University in Tallahassee and colleagues.

19 Oct 2018

New approach to understanding cancers will accelerate development of better treatments

A new innovation in cancer research will enable scientists to understand the complex causes of the disease with unprecedented speed and sophistication. This will accelerate the development of new and better treatments, and it will help researchers find ways around roadblocks that now stand in their path.

19 Oct 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer

With an estimated twenty-thousand protein-coding genes in the human genome, pinpointing a specific gene or pathway responsible for a particular disease can be like finding a needle in the proverbial haystack.

17 Oct 2018

Researchers to develop new stem cell-based strategies for treating vision disorders

A team from the University of Pennsylvania, Children's Hospital of Philadelphia, and University of Wisconsin--Madison are launching a project to develop new strategies for treating vision disorders using cells implanted in the retina.

17 Oct 2018

Researchers discover why heart contractions are weaker in individuals with HCM

When a young athlete suddenly dies of a heart attack, chances are high that they suffer from familial hypertrophic cardiomyopathy. Itis the most common genetic heart disease in the US and affects an estimated 1 in 500 people around the world.

17 Oct 2018

Study of Nigerian breast cancer patients reveals prevalence of aggressive molecular features

A study comparing DNA and RNA data from Nigerian breast cancer patients to patients in a United States database found that certain aggressive molecular features were far more prevalent in tumors from Nigerian women than in black or white American women.

16 Oct 2018

New findings reveal potential cellular players in tumor microenvironment

New findings presented today by CytoReason reveals possible new cellular players in the tumor microenvironment that could impact the treatment process for the most in-need patients - those who have already failed to respond to ipilimumab (anti-CTLA4) immunotherapy.

16 Oct 2018

Study uses novel approach to investigate genetic origins of mental illnesses

A study in Biological Psychiatry has established a new analytical method for investigating the complex genetic origins of mental illnesses using brain cells that are grown in a dish from human embryonic stem cells.

16 Oct 2018

Study uncovers important role of PRMT1 in dilated cardiomyopathy

In a study published in iScience, Professor Akiyoshi Fukamizu of the Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (University of Tsukuba, JAPAN) and the research group reported a new work on discovery of the important role of PRMT1 in dilated cardiomyopathy.

16 Oct 2018

Researchers sequence two selfish genes in the fungus Neurospora intermedia

Selfish genes are genes that are passed on to the next generation but confer no advantage on the individual as a whole, and may sometimes be harmful.

15 Oct 2018

Endurance exercise training beneficially alters gut microbiota composition

According to recent research, endurance exercise training beneficially modifies gut microbiota composition. After six weeks of training, potentially inflammation causing microbes (Proteobacteria) decreased and microbes that are linked to enhanced metabolism (Akkermansia) increased.

15 Oct 2018

Breastfeeding reduces the number of antibiotic-resistant bacteria in infant gut

A new study from the University of Helsinki shows that babies that are breastfed for at least six months have less antibiotic-resistant bacteria in their gut compared with infants breastfed for a shorter time. In addition, antibiotic use by mothers increases the number of antibiotic-resistant bacteria in infants.

15 Oct 2018

Genes News and Research

Dysfunction of single gene leads to miscarriages

Newly discovered compound shows potential for treating Parkinson's disease

Sweat bees are ideal for studying the genes underlying social behavior

LJI and UC San Diego awarded $ 4.5 million as part of NCI's Cancer Moonshot initiative

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

Gene sequencing reveals crucial molecular aspects of Trypanosoma brucei

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

Father’s exposure to nicotine may cause cognitive deficits in descendants

New approach to understanding cancers will accelerate development of better treatments

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer

Researchers to develop new stem cell-based strategies for treating vision disorders

Researchers discover why heart contractions are weaker in individuals with HCM

Study of Nigerian breast cancer patients reveals prevalence of aggressive molecular features

New findings reveal potential cellular players in tumor microenvironment

Study uses novel approach to investigate genetic origins of mental illnesses

Study uncovers important role of PRMT1 in dilated cardiomyopathy

Researchers sequence two selfish genes in the fungus Neurospora intermedia

Endurance exercise training beneficially alters gut microbiota composition

Breastfeeding reduces the number of antibiotic-resistant bacteria in infant gut

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