Genes News and Research

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Fruit fly protein shows protective effect on dopamine-producing neurons

Parkinson's disease is a neurodegenerative disorder that affects dopamine-producing or dopaminergic neurons. The progressive loss of these neurons is what leads to impairment in movement coordination in those suffering from the illness.

3 Oct 2018

Vegetable hormone helps reverse brain alterations caused by high-fat diets, obesity

The Neurobiotechnology research team of the Universitat Jaume I in Castellón, Spain, headed by professor Ana María Sánchez, has proven the positive effects of a vegetable hormone, helping reverse brain alterations caused by high-fat diets, type-2 diabetes, obesity and physical inactivity.

3 Oct 2018

Researchers create pseudo-embryos that mimic human embryos

Researchers have created murine pseudo-embryos that form the three major axes of the body and are able to accurately mimic human embryos.

3 Oct 2018

Researchers insert just enough human DNA into mice to study preterm birth

Preterm birth remains a global epidemic linked to a lifetime of potential health complications. It also is difficult to study in living creatures--especially the uniquely precise biology of preterm birth in humans.

3 Oct 2018

Could 'natural adaptive therapies' be a better way to keep cancer under control?

While many cancer therapies initially can be very successful, tumors often return and spread when remaining cancer cells develop resistance to treatment.

3 Oct 2018

Gene variant linked to Type 2 diabetes may predispose people to have lower body weight

A research team at the University of North Carolina at Chapel Hill's Gillings School of Global Public Health found that a well-known gene variant linked to Type 2 diabetes, called transcription Factor-7 like 2 gene, may also predispose someone to being leaner, or having a lower body weight.

3 Oct 2018

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases. But if the new, engineered genes can't find their way into the patient's genomic sequence, they won't help.

3 Oct 2018

USDA scientist tries to naturally enhance minerals of wheat flours

Is biofortification the best thing since sliced bread? Well, biofortified wheat could certainly make it easier to help some humans get proper nutrition.

3 Oct 2018

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, have identified the mechanism by which an important enzyme involved in the differentiation of stem cells is brought to the DNA.

3 Oct 2018

Study highlights need for population-specific precision medicine programs in Latin America

Drug safety and effectiveness vary greatly among populations worldwide. Genetics is one of the factors that contribute to variability in drug response.

3 Oct 2018

Nanoparticles show promise in treatment for triple-negative breast cancer, finds study

Approximately 10-20 percent of diagnosed breast cancers are found to be triple-negative, meaning the breast cancer cells test negative for estrogen and progesterone receptors as well as HER2 receptors, genes that can play a role in the development of breast cancer.

1 Oct 2018

Study: Phyloplankton's ability to generate resting stages plays key role in genetic differences

The genetic differences in phyloplankton living in close geographic proximity can be great, something which long has surprised researchers. Now new research shows that the ability of phyloplankton to generate resting stages can be an important part of the explanation.

1 Oct 2018

Study finds disease-causing mutation in French-Canadians

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson's disease, dementia with Lewy-Bodies and multiple system atrophy

1 Oct 2018

New, more efficient method for generating brain stem cells in the lab

In two newly published papers, a scientific team at Case Western Reserve University School of Medicine reports on the discovery and implementation of a new, more efficient method for generating an important brain stem cell in the laboratory.

1 Oct 2018

Mediterranean diet cuts risk of developing AMD

Evidence is mounting that a poor diet plays an important role in the development of age-related macular degeneration, a leading cause of blindness in the United States.

1 Oct 2018

Genetic variants reveal novel therapeutic targets for chronic kidney disease

The kidney does more than double or even triple duty compared to other organs - it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones.

1 Oct 2018

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.

1 Oct 2018

Researchers identify genes that could help predict treatment outcomes for parasitic disease

Researchers at the University of York have identified genes in a parasite that could help clinicians predict drug treatment outcomes for patients with visceral leishmaniasis in Brazil.

1 Oct 2018

New project identifies immune checkpoint inhibition as potential treatment for angiosarcomas

Angiosarcoma Project, a patient-partnered genomics study, identified immune checkpoint inhibition as a potential treatment option for patients with angiosarcomas of the head, face, neck, or scalp, according to data presented at the fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference.

1 Oct 2018

Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

Genes News and Research

Fruit fly protein shows protective effect on dopamine-producing neurons

Vegetable hormone helps reverse brain alterations caused by high-fat diets, obesity

Researchers create pseudo-embryos that mimic human embryos

Researchers insert just enough human DNA into mice to study preterm birth

Could 'natural adaptive therapies' be a better way to keep cancer under control?

Gene variant linked to Type 2 diabetes may predispose people to have lower body weight

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

USDA scientist tries to naturally enhance minerals of wheat flours

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

Study highlights need for population-specific precision medicine programs in Latin America

Nanoparticles show promise in treatment for triple-negative breast cancer, finds study

Study: Phyloplankton's ability to generate resting stages plays key role in genetic differences

Study finds disease-causing mutation in French-Canadians

New, more efficient method for generating brain stem cells in the lab

Mediterranean diet cuts risk of developing AMD

Genetic variants reveal novel therapeutic targets for chronic kidney disease

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

Researchers identify genes that could help predict treatment outcomes for parasitic disease

New project identifies immune checkpoint inhibition as potential treatment for angiosarcomas

Researchers deplete key protein for DNA replication using protein degradation system

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