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Elevated troponin I should not rule out donor hearts

Donor cardiac troponin I level is not associated with intermediate-term mortality, cardiac allograft vasculopathy or primary graft failure in patients receiving heart transplants, US researchers report.

28 Jun 2016

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others.

28 Jun 2016

TSRI scientists identify GlyRS protein that launches cancer growth

Scientists at The Scripps Research Institute have identified a protein that launches cancer growth and appears to contribute to higher mortality in breast cancer patients.

28 Jun 2016

MLDA of 21 appears to protect against alcohol-related mortality later in life

The minimum legal drinking age (MLDA) in the U.S. regulates the age at which individuals can legally purchase and possess alcohol in public. An MLDA of 21 has been linked to a number of benefits, including a lower risk for alcoholism in adulthood.

25 Jun 2016

Race impacts adverse outcomes in atrial fibrillation

Black individuals with atrial fibrillation have markedly higher rates of stroke, heart failure, coronary heart disease and mortality than their White counterparts, data from the Atherosclerosis Risk in Communities study show.

24 Jun 2016

The future of simulated teaching methods

In healthcare, we have physicians, nurses and paramedics who know the textbook by heart and know exactly what they need to do, but have never experienced the procedure first-hand, or they have no experience responding to adverse events that may occur.

24 Jun 2016

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting.

24 Jun 2016

Diabetes, kidney disease may play role in increasing adverse cardiovascular outcomes among African Americans

New research indicates that diabetes and kidney disease may increase African Americans' risk of stroke and coronary heart disease, as well as their risk of dying from cardiovascular causes.

24 Jun 2016

Increase in EPA/DHA omega-3 intake linked to lower risk of all-cause mortality

A recent meta-analysis in Scientific Reports supports a link between EPA and DHA omega-3 intake and a reduced risk of death by any cause. The meta-analysis included 11 studies involving 371,965 participants and 31,185 death events, with a subset of the studies being used for different analyses.

23 Jun 2016

Adherence to cancer prevention guidelines on diet and physical activity may reduce disease incidence

"Behaviors such as poor diet choices, physical inactivity, excess alcohol consumption and unhealthy body weight could account for more than 20 percent of cancer cases, and could, therefore, be prevented with lifestyle modifications," Kohler said, adding that when tobacco exposure is considered, these modifiable issues are believed to be factors in two-thirds of U.S. cancer deaths.

23 Jun 2016

Study provides new ways to avert annual heat-related deaths

By the 2080s, as many as 3,331 people could die every year from exposure to heat during the summer months in New York City. The high estimate by Columbia University scientists is based on a new model--the first to account for variability in future population size, greenhouse gas trajectories, and the extent to which residents adapt to heat through interventions like air conditioning and public cooling centers.

23 Jun 2016

Two simple measures can help decrease incidence of POCD in older patients

Post-operative cognitive dysfunction (POCD), a condition mostly observed in older patients following surgery under general anesthesia, is characterized by impaired memory and concentration. The impairment may be temporary or permanent and incapacitating.

23 Jun 2016

NOACs match warfarin for atrial fibrillation

Real-world study data from Denmark show that non-vitamin K antagonist oral anticoagulants are effective alternatives to warfarin in patients with non-valvular atrial fibrillation in a routine care setting.

23 Jun 2016

Study finds ARNI therapy could potentially prevent 28,484 deaths from heart failure each year

A UCLA-led study estimates that almost 28,500 deaths could be prevented each year in the U.S. through use of a new FDA-approved class of cardiovascular medication that helps reduce mortality in patients diagnosed with heart failure and reduced ejection fraction, the percentage of blood pumped from the heart with each contraction.

22 Jun 2016

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Few threats to public health are as perilous as cigarette smoking, with more than 435,000 Americans dying each year of tobacco-related pulmonary illnesses such as chronic obstructive pulmonary disease (COPD).

22 Jun 2016

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

A new meta-analysis published in Clinical Nutrition found that cardiac surgery patients who received omega-3 polyunsaturated fatty acids (compared to placebo) in advance of surgery experienced reduced postoperative cardiac arrhythmias and significantly reduced the length of hospital stay by up to 2.4 days. The results are based on 11 RCT's with 1038 patients.

21 Jun 2016

Experts develop set of resolutions, conclusions to provide clarity on testosterone therapy

In an effort to address widespread concerns related to testosterone deficiency (TD) and its treatment with testosterone therapy, a group of international experts has developed a set of resolutions and conclusions to provide clarity for physicians and patients.

21 Jun 2016

Certain leisure activities may lower risk of post-operative delirium in older adults

Delirium, or the medical term for experiencing sudden confusion, is upsetting for both older adults and their families. In fact, it is one of the most common complications older adults face after surgery (a time often referred to as the "post-operative" period).

21 Jun 2016

Scientists identify on/off obesity-induced switch to slow cancer progression

Having established that excessive fat tissue can fuel the growth of certain cancers, researchers have turned their attention to the molecular mechanisms involved in the process in the hopes of developing new cancer treatments.

21 Jun 2016

Fixed-dose combination of sacubitril and valsartan for heart failure shows differing added benefit

The fixed-dose combination of sacubitril and valsartan (trade name: Entresto) has been approved since November 2015 for adults with symptomatic chronic heart failure with reduced pump function.

21 Jun 2016

Mortality News and Research

Elevated troponin I should not rule out donor hearts

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

TSRI scientists identify GlyRS protein that launches cancer growth

MLDA of 21 appears to protect against alcohol-related mortality later in life

Race impacts adverse outcomes in atrial fibrillation

The future of simulated teaching methods

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Diabetes, kidney disease may play role in increasing adverse cardiovascular outcomes among African Americans

Increase in EPA/DHA omega-3 intake linked to lower risk of all-cause mortality

Adherence to cancer prevention guidelines on diet and physical activity may reduce disease incidence

Study provides new ways to avert annual heat-related deaths

Two simple measures can help decrease incidence of POCD in older patients

NOACs match warfarin for atrial fibrillation

Study finds ARNI therapy could potentially prevent 28,484 deaths from heart failure each year

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

Experts develop set of resolutions, conclusions to provide clarity on testosterone therapy

Certain leisure activities may lower risk of post-operative delirium in older adults

Scientists identify on/off obesity-induced switch to slow cancer progression

Fixed-dose combination of sacubitril and valsartan for heart failure shows differing added benefit

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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