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High or rapidly rising BP poses greatest stroke, mortality risk

Findings from the Rotterdam study show how the trajectories of people's blood pressure in mid to late life have varying effects on their risk of having a stroke or dying.

17 May 2016

RDAVR system improves survival of patients with severe aortic stenosis

When replacing a defective aortic valve with a new one, restoring function is the first priority. However, variables such as durability, length of surgery, duration of heart stoppage, size of the surgical incision, postoperative pain, and complications are other important considerations.

17 May 2016

Fitness may preserve lung function as we age

Being fit may reduce the decline in lung function that occurs as we grow older, according to research presented at the ATS 2016 International Conference.

17 May 2016

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Eisai Co., Ltd. has announced that its U.S. subsidiary Eisai Inc. has received approval from the U.S. Food and Drug Administration (FDA) for an additional indication for Eisai's in-house developed novel anticancer agent Lenvima (lenvatinib mesylate) in combination with everolimus for the treatment of patients with advanced renal cell carcinoma following one prior anti-angiogenic therapy.

16 May 2016

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

Myocardial fibrosis could be a future therapeutic target after researchers found it correlated with adverse cardiovascular outcomes in patients with obstructive sleep apnoea (OSA) referred for cardiac magnetic resonance (CMR).

13 May 2016

Study finds no link between weekend staffing levels and patient deaths

The ‘weekend effect’ – that patients admitted to hospital over the weekend are at an increased risk of death – overshadows a much more complex pattern of weekly changes in quality of care, which are unlikely to be addressed by simply increasing the availability of hospital doctors on Saturdays and Sundays, according to two new studies published in The Lancet.

13 May 2016

Sexual abstinence, marital fidelity programs not effective in reducing HIV risk

The U.S. government has invested $1.4 billion in HIV prevention programs that promote sexual abstinence and marital fidelity, but there is no evidence that these programs have been effective at changing sexual behavior and reducing HIV risk, according to a new Stanford University School of Medicine study.

13 May 2016

Estrogen-inhibiting drug may suppress dangerous brain seizures

A class of drug that inhibits estrogen production and is used to treat breast cancer has been found to quickly and effectively suppress dangerous brain seizures, according to a new Northwestern University study.

13 May 2016

Point-of-care test could help detect TB in HIV-positive individuals

An international review team has prepared a Cochrane systematic review to assess the accuracy of a point-of-care urine test for diagnosing and screening tuberculosis (TB) in people living with human immunodeficiency virus (HIV).

12 May 2016

People in low-income communities more likely to be hospitalized for AMI

While heart attack rates across all income levels have declined significantly over the last 15 years, people living in low-income communities are still more likely to be hospitalized for acute myocardial infarction (AMI), according to a new study published by Yale School of Medicine researchers in the journal JAMA Cardiology.

12 May 2016

Children of depressed parents more likely to have recurrent episodes of depression, poor outcomes in adulthood

The latest report from a 30-year study of families at high- and low-risk for depression reveals that the offspring of depressed parents have a higher risk for depression, morbidity and mortality that persists into middle age.

12 May 2016

New research shows all-cause mortality linked to obesity has decreased over past 40 years

New research from Denmark involving more than 100,000 individuals suggests that the excess risk of premature death associated with obesity has decreased over the past 40 years.

11 May 2016

Innovative technology in NICU can predict risk of major infections in premature or critically ill babies

A new technology in the Neonatal Intensive Care Unit at UC San Diego Health is able to predict the risk of life-threatening infections up to 24 hours before they appear in severely premature or critically ill infants. Infection is the leading cause of death in this fragile patient population.

11 May 2016

Researchers find increase in BMI value associated with lowest all-cause mortality

In a study appearing in the May 10 issue of JAMA, Børge G. Nordestgaard, M.D., D.M.Sc., of Copenhagen University Hospital, Herlev, Denmark and colleagues examined whether the body mass index (BMI) value that is associated with the lowest all-cause mortality has increased in the general population over a period of 3 decades.

11 May 2016

Daiichi buys Japanese rights to CTL’s innovative cardiac regeneration medicine, Heartcel

Cell Therapy Ltd. today announced the granting of the Japan license for its innovative cardiac regeneration medicine, Heartcel™ (immuno-modulatory progenitor [iMP] cells) to Daiichi Sankyo.

11 May 2016

ENCHANTED results challenge reduced alteplase dose in Asian stroke patients

A reduced dose of alteplase has failed to prove itself noninferior to the standard dose in a predominantly Asian population of patients with ischaemic stroke.

11 May 2016

Depression course predicts dementia risk

Patients with late-life depression have an increased risk of dementia if their symptoms increase over time, whereas a single episode of depression, even if severe, does not carry a significant risk, study findings indicate.

10 May 2016

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

The Medical University of South Carolina's Hollings Cancer Center received an $8.9 million grant from the National Cancer Institute designed to foster collaboration across clinical and laboratory research for the study of signaling in sphingolipids, a class of lipids known to be involved in the growth of solid tumor cancers.

10 May 2016

Experimental vaccine protects healthy U.S. adults from malaria infection for more than one year

An experimental malaria vaccine protected a small number of healthy, malaria-naïve adults in the United States from infection for more than one year after immunization, according to results from a Phase 1 trial described in the May 9th issue of Nature Medicine.

10 May 2016

New set of practice guidelines from WMS may help in treatment, prevention of drowning

Drowning is a global threat to human health. Each year, more than 372,000 people die as a result of drowning, with many of those deaths being preventable by simple water safety measures. In order to arm professionals with the most up-to-date clinical protocols, the Wilderness Medical Society has issued a new set of practice guidelines for both the treatment and prevention of drowning, published in the society's official journal, Wilderness and Environmental Medicine.

10 May 2016

Mortality News and Research

High or rapidly rising BP poses greatest stroke, mortality risk

RDAVR system improves survival of patients with severe aortic stenosis

Fitness may preserve lung function as we age

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

Study finds no link between weekend staffing levels and patient deaths

Sexual abstinence, marital fidelity programs not effective in reducing HIV risk

Estrogen-inhibiting drug may suppress dangerous brain seizures

Point-of-care test could help detect TB in HIV-positive individuals

People in low-income communities more likely to be hospitalized for AMI

Children of depressed parents more likely to have recurrent episodes of depression, poor outcomes in adulthood

New research shows all-cause mortality linked to obesity has decreased over past 40 years

Innovative technology in NICU can predict risk of major infections in premature or critically ill babies

Researchers find increase in BMI value associated with lowest all-cause mortality

Daiichi buys Japanese rights to CTL’s innovative cardiac regeneration medicine, Heartcel

ENCHANTED results challenge reduced alteplase dose in Asian stroke patients

Depression course predicts dementia risk

MUSC Hollings Cancer Center receives $8.9 million grant to explore signaling in sphingolipids

Experimental vaccine protects healthy U.S. adults from malaria infection for more than one year

New set of practice guidelines from WMS may help in treatment, prevention of drowning

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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