Genes News and Research

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Neuroscientists identify new type of “rose hip” neurons unique to humans

A unique type of neuron has been discovered in the human brain. It has been termed the “rose hip” neuron after the base of the rose which it resembles. This neuron is absent in mice and may provide clues about what makes the human brain unique.

27 Aug 2018

Discovery will allow scientists to target hypoxia in cancer

Researchers have discovered a new GPCR that will allow them to target hypoxia in cancer, offering a new, less harmful treatment for patients.

27 Aug 2018

Restricting consumption of high-sucrose diet to active part of day avoids adverse effects in rats

A sedentary lifestyle combined with a diet dominated by processed foods has widely resulted in a range of conditions including diabetes, obesity, and high blood pressure, which are known collectively as metabolic syndrome.

27 Aug 2018

Changes in TRPV3 genes may have helped mammoths withstand lower temperatures

Columbia University biomedical researchers have captured close-up views of TRPV3, a skin-cell ion channel that plays important roles in sensing temperature, itch, and pain.

25 Aug 2018

Study reveals molecular mechanisms underlying expansive arterial remodeling

Expansive arterial remodeling comprises a genetically programmed biological response designed to restore homeostatic levels of arterial wall stress after an increase in vessel flow load occurs.

25 Aug 2018

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

Inhibition of miR-24-3p reduced growth of cancer cells and was found to regulate proteins as a potential treatment target for Mesothelioma.

25 Aug 2018

Research into biology behind sperm development could offer hope for solving male infertility

Nearly one in eight couples in the U.S. face infertility, and about half of those cases can be attributed to semen abnormalities in the male partner.

24 Aug 2018

Study finds how animal guts have evolved to defend themselves from microbial attack

A new Nature Communications paper has journeyed to the inside of our insides, as a team from the Okinawa Institute of Science and Technology Graduate University has mapped the evolutionary journey of how animal guts have evolved to defend themselves from microbial attack.

24 Aug 2018

Researchers find new therapy to prevent drug resistance for melanoma patients

Mount Sinai researchers have discovered a previously unknown reason for drug resistance in a common subtype of melanoma, one of the deadliest forms of cancer, and in turn, have found a new therapy that could prevent or reverse drug resistance for melanoma patients with a particular gene mutation, according to a study published in Nature Communications in August.

24 Aug 2018

Genetic interindividual variability influences nutritional requirements

Approximately 0.1%: that is the average genetic difference between two individuals. This small percentage is responsible for the variations of certain physical traits, such as eyes, hair, and height, but also for differences in our susceptibility to certain diseases and our capacity to absorb vitamins and phytomicronutrients, involved in the prevention of chronic disease.

24 Aug 2018

Researchers uncover how RNA regulates genes during critical stage in embryonic brain development

Scientists at the Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and colleagues discovered how a type of RNA, called Evf2 enhancer RNA, regulates key genes during a critical stage in embryonic brain development.

24 Aug 2018

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

St. Jude Children's Research Hospital investigators have completed the most comprehensive analysis yet of a common pediatric solid tumor, identifying weaknesses to target and a promising precision medicine that is now in clinical trials.

23 Aug 2018

Study suggests new possibilities for treating metabolic syndrome

New research, in mice, indicates that a natural sugar called trehalose blocks glucose from the liver and activates a gene that boosts insulin sensitivity, reducing the chance of developing diabetes. Activating the gene also triggers an increase in calories burned, reduces fat accumulation and weight gain, and lessens measures of fats and cholesterol in the blood.

23 Aug 2018

Sleep loss can confer increased risk of adverse weight gain, shows study

In a new study, researchers at Uppsala University now demonstrate that one night of sleep loss has a tissue-specific impact on the regulation of gene expression and metabolism in humans.

23 Aug 2018

Individual hypertensive responses to antibiotics may vary depending on genetic makeup and gut bacteria

Individual variations in genetic makeup and gut bacteria may explain the different effects of antibiotics on blood pressure, a new rat study suggests. The findings are published ahead of print in Physiological Genomics.

23 Aug 2018

Scientists work towards solving mystery of incurable blood diseases

Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes, which cause people to have immature, malfunctioning bone marrow cells that fuel a diverse set of health problems and can lead to leukemia.

23 Aug 2018

Advanced sequencing of nasal polyps provides new insights into allergic conditions

Nasal polyps - soft, grape-like outgrowths that can appear in the nasal passages and sinuses - can be chronic and relentless. Although noncancerous, these outgrowths can grow large enough to block the nose and sinuses, leading to discomfort, breathing problems and infections.

22 Aug 2018

Genetic variants impact outcome in dilated cardiomyopathy patients of African ancestry

Genetic testing is a powerful diagnostic tool that is increasingly being used for the diagnosis of dilated cardiomyopathy, a disease in which the heart becomes enlarged, making it difficult to pump blood. Cardiomyopathy affects more than 3.5 million people in the United States.

22 Aug 2018

Researchers develop faster method to grow brain cells from stem cells

Researchers at Lund University in Sweden have developed a faster method to generate functional brain cells, called astrocytes, from embryonic stem cells. Astrocytes play a significant role in neurodegenerative diseases.

22 Aug 2018

UCLA professor shares five facts about ovarian cancer

Ovarian cancer can be beat. Dr. Sanaz Memarzadeh, a UCLA professor in obstetrics and gynecology and member of the UCLA Jonsson Comprehensive Cancer Center, is convinced of it.

22 Aug 2018

Genes News and Research

Neuroscientists identify new type of “rose hip” neurons unique to humans

Discovery will allow scientists to target hypoxia in cancer

Restricting consumption of high-sucrose diet to active part of day avoids adverse effects in rats

Changes in TRPV3 genes may have helped mammoths withstand lower temperatures

Study reveals molecular mechanisms underlying expansive arterial remodeling

Inhibition of miR-24-3p may serve as potential treatment target for mesothelioma

Research into biology behind sperm development could offer hope for solving male infertility

Study finds how animal guts have evolved to defend themselves from microbial attack

Researchers find new therapy to prevent drug resistance for melanoma patients

Genetic interindividual variability influences nutritional requirements

Researchers uncover how RNA regulates genes during critical stage in embryonic brain development

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

Study suggests new possibilities for treating metabolic syndrome

Sleep loss can confer increased risk of adverse weight gain, shows study

Individual hypertensive responses to antibiotics may vary depending on genetic makeup and gut bacteria

Scientists work towards solving mystery of incurable blood diseases

Advanced sequencing of nasal polyps provides new insights into allergic conditions

Genetic variants impact outcome in dilated cardiomyopathy patients of African ancestry

Researchers develop faster method to grow brain cells from stem cells

UCLA professor shares five facts about ovarian cancer

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