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Radiotherapy needs likely to increase in all European countries by 2025

The demand for radiotherapy across all European countries will increase by an average of 16% between 2012 and 2025, with the highest expected increase being for prostate cancer cases (24%), according to a new study published in Radiotherapy and Oncology.

19 Apr 2016

Article highlights some of key disparities affecting women of color

Women of color face both racial and gender disparities in the incidence, onset, and outcomes of diseases as diverse as cancer, cardiovascular disease, HIV infection and age-related disability.

18 Apr 2016

Green vegetation near homes plays important role in reducing mortality

Women live longer in areas with more green vegetation, according to new research funded by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health. Women with the highest levels of vegetation, or greenness, near their homes had a 12 percent lower death rate compared to women with the lowest levels of vegetation near their homes. The results were published Apr. 14, 2016 in the journal Environmental Health Perspectives.

18 Apr 2016

FOXO proteins affect dozens of genes common to worms, flies, mice and humans

Whether a creature is a worm, a fly, a mouse, or a human, death inevitably awaits. And not only do these organisms share a common fate, but also, according to a new study, they may share some of the specific mechanisms of mortality. The researchers found that in all four species, there are 46 genes regulated by the same family of "FOXO" proteins known to be central in aging and longevity.

16 Apr 2016

Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

A nationwide study of 2.3 million Israeli adolescents, examined from 1967 through 2010, finds an association between elevated body-mass index in late adolescence, and subsequent cardiovascular mortality in midlife.

16 Apr 2016

New study links high-volume lung transplant centers with lower costs, readmissions

High-volume lung transplant centers have lower transplantation costs and their patients are less likely to be readmitted within 30 days of leaving the hospital following surgery, according to a new study of more than 3,000 Medicare patients who received lung transplants.

16 Apr 2016

Deadly ‘Crypto’ pathogen lures US researcher to UQ

Cryptococcus is so forsaken by research that it doesn’t even make the neglected diseases list – but the deadly fungal pathogen has lured an American scientist all the way to The University of Queensland.

14 Apr 2016

Physicians failing to talk to stroke patients about end-of-life treatment preferences

US research suggests that physician-patient discussion about limitations on life-sustaining interventions following ischaemic stroke is low, poorly documented and often left too late.

14 Apr 2016

Hospitals could reduce burden of alcohol-related liver disease through universal screening procedure

The growing burden of alcohol-related liver disease (ARLD) could be reduced if hospitals introduced a simple universal screening procedure for those attending acute and emergency hospital settings, according to a new study shared today at The International Liver Congress in Barcelona, Spain.

13 Apr 2016

High levels of COMP protein may lead to worse breast cancer prognosis

Research from Lund University in Sweden shows that the protein COMP, which mainly exists in cartilage, can also be found in breast cancer tumours in patients with a poor prognosis. Studies on mice also showed that COMP contributed to the development and metastasis of the breast cancer.

13 Apr 2016

Quality improvement intervention in ICUs does not reduce in-hospital mortality, study reveals

Implementation of a multifaceted quality improvement intervention with daily checklists, goal setting, and clinician prompting did not reduce in-hospital mortality compared with routine care among critically ill patients treated in intensive care units (ICUs) in Brazil, according to a study appearing in the April 12 issue of JAMA.

13 Apr 2016

New clinical data highlights potential of AB-PA01 to treat P. aeruginosa infections in CF patients

AmpliPhi Biosciences Corporation, a global leader in the development of bacteriophage-based antibacterial therapies to treat drug-resistant infections, presented data at the European Congress of Clinical Microbiology and Infectious Diseases summarizing both the in vitro and in vivo activity of its proprietary, investigational phage mix AB-PA01.

13 Apr 2016

Weekend effect in hospitals affect kidney stone treatment, outcomes

Patients with severe cases of kidney stones are 26 percent less likely to receive timely treatment when they're admitted to the hospital on the weekend, according to a study by researchers at Loyola Medicine and Loyola University Chicago Stritch School of Medicine.

12 Apr 2016

Pericardial window operation not effective in lung cancer cases, say researchers

Pericardial window operation, a procedure, where abnormal quantity of malignant fluid, or malignant pericardial effusion (MPE), surrounding the heart, is drained into the neighbouring chest cavity through a surgically placed tube, is commonly applied to patients diagnosed with cancer.

12 Apr 2016

Increased BMP7 levels predict PAH mortality

Elevated levels of circulating bone morphogenetic protein 7 are associated with an increased mortality risk in patients with pulmonary arterial hypertension, find Chinese researchers.

12 Apr 2016

BMPR2 mutations affect outcomes of PAH patients

Mutations in the bone morphogenetic protein receptor type II gene affect not only the risk of developing pulmonary arterial hypertension but also the severity and outcomes of the disease, shows a meta-analysis of individual patient data.

12 Apr 2016

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

In a new study, researchers from Columbia University Medical Center described a new mouse model featuring a combination of genetic and environmental risk factors that can trigger the compulsive restriction of food intake seen in patients with anorexia nervosa. The findings may help to identify new prevention and treatment strategies for the eating disorder in humans.

12 Apr 2016

Marriage may help prolong survival in cancer patients

New research has uncovered a link between being married and living longer among cancer patients, with the beneficial effect of marriage differing by race/ethnicity and place of birth. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings have important public health implications, given the rising numbers of unmarried individuals in the United States in addition to the growing aging population.

12 Apr 2016

Pooled analysis from seven clinical studies demonstrates consistent efficacy for ceftazidime-avibactam in the treatment of multi-drug resistant gram-negative bacteria

AstraZeneca has presented positive data demonstrating the efficacy of the investigational antibiotic, ceftazidime-avibactam (CAZ-AVI), in treating patients with ceftazidime-resistant Gram-negative infections, which are increasingly resistant to most available antibiotics, often precipitating the need for clinicians to reach for agents previously reserved for last-line use.

12 Apr 2016

Advanced assay offers better sensitivity for detecting a prion disease affecting elk

Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a family of rare progressive, neurodegenerative illnesses that affect both humans and animals. TSE surveillance is important for public health and food safety because TSEs have the potential of crossing from animals to humans, as seen with the spread of mad cow disease, or bovine spongiform encephalopathy (BSE). A study in The Journal of Molecular Diagnostics describes an advanced assay that offers better sensitivity than currently available tests for detecting a prion disease affecting elk.

11 Apr 2016

Mortality News and Research

Radiotherapy needs likely to increase in all European countries by 2025

Article highlights some of key disparities affecting women of color

Green vegetation near homes plays important role in reducing mortality

FOXO proteins affect dozens of genes common to worms, flies, mice and humans

Adolescent obesity linked to elevated risk of cardiovascular mortality in midlife

New study links high-volume lung transplant centers with lower costs, readmissions

Deadly ‘Crypto’ pathogen lures US researcher to UQ

Physicians failing to talk to stroke patients about end-of-life treatment preferences

Hospitals could reduce burden of alcohol-related liver disease through universal screening procedure

High levels of COMP protein may lead to worse breast cancer prognosis

Quality improvement intervention in ICUs does not reduce in-hospital mortality, study reveals

New clinical data highlights potential of AB-PA01 to treat P. aeruginosa infections in CF patients

Weekend effect in hospitals affect kidney stone treatment, outcomes

Pericardial window operation not effective in lung cancer cases, say researchers

Increased BMP7 levels predict PAH mortality

BMPR2 mutations affect outcomes of PAH patients

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

Marriage may help prolong survival in cancer patients

Pooled analysis from seven clinical studies demonstrates consistent efficacy for ceftazidime-avibactam in the treatment of multi-drug resistant gram-negative bacteria

Advanced assay offers better sensitivity for detecting a prion disease affecting elk

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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