Angiotensin News and Research

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Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.

The antiviral function of BET protein against SARS-CoV-2 infection

Considering the past shreds of evidence on BRD2 and BRD4 associated with viral infections, researchers have recently evaluated the function of all relevant BET proteins during COVID-19 infection.

17 Nov 2021

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Researchers used advanced two-color fluorescence cross-correlation spectroscopy to demonstrate the interaction between human ACE2 and the S1 subunit of SARS-CoV-2 and SARS-CoV.

17 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

How effective is the COMIRNATY BNT162b2 vaccine against the SARS-CoV-2 Lambda variant?

Now, researchers from Public Health Services Israel have been investigating a new variant called Lambda to see if it qualifies as a variant of concern. Their research is published in the journal Eurosurveillance.

16 Nov 2021

Drug improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy

Valsartan, an angiotensin II receptor blocker drug, delayed disease progression and improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy, according to results from a recent clinical trial published in Nature Medicine.

16 Nov 2021

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Researchers recently conducted a study to identify host factors affecting cellular interactions of the SARS-CoV-2 spike protein.

16 Nov 2021

SARS-CoV-2 replicates in human placenta with release of infectious viral particles

The current study analyzed the interaction of SARS-CoV-2 at the human maternal-fetal interface by using an advanced ex vivo model.

16 Nov 2021

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

A new study has described the molecular basis of the neutralization potency and breadth of nanobodies.

16 Nov 2021

Rapid finger stick test to detect antibodies against SARS-CoV-2 variants

A new preprint reports a semi-quantitative test that can measure neutralizing antibodies to the SARS-CoV-2 pathogen at the point of care, using a finger stick or venipuncture blood.

16 Nov 2021

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

A recent study investigates histone mimicry as a mechanism by SARS-CoV-2 for disrupting epigenetic regulation to evade host cell responses to infection.

15 Nov 2021

Common hypertension drug not effective in slowing down the progression of Alzheimer's disease

New research led by the University of Bristol, has shown the drug losartan, normally used to treat high blood pressure (hypertension), is not effective in slowing down the progression of Alzheimer's disease (AD) in people with mild-to-moderate disease after 12 months of treatment.

15 Nov 2021

Could drugs derived from microalgae be effective against COVID-19?

Researchers discuss the ability of some microalgae metabolites to prevent cytokine storm syndrome during COVID-19.

15 Nov 2021

Vaccination protects against COVID-19 related hospitalization in patients with and without comorbidity

Researchers from University Medical Centre Utrecht have been investigating the efficiency of vaccines against the alpha variant in the Netherlands.

15 Nov 2021

Detection of a coronavirus similar to SARS-CoV-2 in Cambodian bats

Now, a new study published in the journal Nature Communications reports the identification of SARS-CoV-2 related coronaviruses in two horseshoe bats sampled in Cambodia in 2010.

15 Nov 2021

Mycobacterium tuberculosis may induce resistance to secondary SARS-CoV-2 infection

The current study reveals that mice infected with mycobacterium tuberculosis are resistant to SARS-CoV-2 infection.

14 Nov 2021

Partial resistance to neutralizing antibodies and enhanced transmissibility of SARS-CoV-2 Delta variant

A new study estimates the efficacy of the immune response induced by vaccination and natural COVID-19 infection against the Kappa and Delta lineages.

14 Nov 2021

Impact of mutations on binding affinity of SARS-CoV-2 variants with ACE2 and existing antibodies

Researchers explained their analysis of the mechanisms that trigger the docking of SARS-CoV-2 variants to ACE2 and the antibodies, referred to as protein-protein docking.

12 Nov 2021

Study may pave the way for a more personalized approach to COVID-19 diagnosis and treatment

Using some of the most advanced molecular sequencing tools available to evaluate COVID-19 rapid autopsy tissues, researchers have identified four major regulatory pathways, specific molecular effectors behind COVID-19 symptoms, and differences that drive diverging clinical courses among individual patients.

11 Nov 2021

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

A team of scientists describe the safety and response to REGEN-COV® for COVID-19 patients with immunodeficiency-associated antibody disorders.

11 Nov 2021

Long-lasting anti-spike and anti-membrane antibodies can differentiate between COVID-19 infection and vaccination

Researchers have been investigating which other proteins remain prevalent long enough for tests against them to be worthwhile.

11 Nov 2021

Angiotensin News and Research

Further Reading

The antiviral function of BET protein against SARS-CoV-2 infection

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

What genes affect the COVID-19 gender imbalance?

How effective is the COMIRNATY BNT162b2 vaccine against the SARS-CoV-2 Lambda variant?

Drug improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

SARS-CoV-2 replicates in human placenta with release of infectious viral particles

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

Rapid finger stick test to detect antibodies against SARS-CoV-2 variants

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

Common hypertension drug not effective in slowing down the progression of Alzheimer's disease

Could drugs derived from microalgae be effective against COVID-19?

Vaccination protects against COVID-19 related hospitalization in patients with and without comorbidity

Detection of a coronavirus similar to SARS-CoV-2 in Cambodian bats

Mycobacterium tuberculosis may induce resistance to secondary SARS-CoV-2 infection

Partial resistance to neutralizing antibodies and enhanced transmissibility of SARS-CoV-2 Delta variant

Impact of mutations on binding affinity of SARS-CoV-2 variants with ACE2 and existing antibodies

Study may pave the way for a more personalized approach to COVID-19 diagnosis and treatment

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

Long-lasting anti-spike and anti-membrane antibodies can differentiate between COVID-19 infection and vaccination

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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