Chimeric Antigen Receptor News and Research

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New injectable polymer could strengthen blood clots

Most military battlefield casualties die before ever reaching a surgical hospital. Of those soldiers who might potentially survive, most die from uncontrolled bleeding.

11 Mar 2015

Repeatedly exposing children to secondhand smoke is child abuse, argues Adam Goldstein

Purposefully and repeatedly exposing children to secondhand smoke — a known human carcinogen — is child abuse, according to an opinion piece written by Adam Goldstein, MD, MPH, a professor in the Department of Family Medicine at the University of North Carolina School of Medicine.

11 Mar 2015

In-car alarm could reduce crashes for young and old drivers

An in-car alarm that sounds when sensors on the vehicle detect an imminent crash could cut crash rates from 1 in 5 to 1 in 10 for drivers over the of 60 suffering tiredness on long journeys, according to a study published in the International Journal of Human Factors and Ergonomics.

11 Mar 2015

Wings for Life World Run to fund breakthrough clinical study on spinal cord injury

It all started with a single toe. Even today, Dr. Susan Harkema recalls the words spoken by one of the research participants: "Look Susie, I can move my toe." The patient's name was Rob Summers and he was completely paralyzed from the neck down. After a car accident he was told he would never be able to walk again.

6 Mar 2015

Researchers one step closer to unraveling complex processes crucial to sperm development

Researchers are one step closer to unraveling the extraordinarily complex series of processes that leads to an event crucial to human reproduction: the creation of sperm.

5 Mar 2015

Neuroscientists find new pathway that allows several brain areas communicate within striatum

Carnegie Mellon University neuroscientists have identified a new pathway by which several brain areas communicate within the brain's striatum.

4 Mar 2015

Study results pave way for new clinical trial for glioblastoma patients

Immune cells engineered to seek out and attack a type of deadly brain cancer were found to be both safe and effective at controlling tumor growth in mice that were treated with these modified cells, according to a study published in Science Translational Medicine by a team from the Perelman School of Medicine at the University of Pennsylvania and the Novartis Institutes for BioMedical Research.

19 Feb 2015

Findings may help doctors recommend appropriate treatments, improve patient outcomes

Like a car's front and back bumpers, your cell's chromosomes are capped by "telomeres" that protect this genetic material against deterioration. Still, after enough replications, a chromosome's telomeres break down and once they reach a certain point of degradation, the cell dies. This is one reason that cells are mortal: telomeres only last so long. That is, unless the enzyme telomerase builds new material onto the worn telomeres to reinforce these chromosomal "bumpers". Telomere repair can be a good thing, but in some cases it's not: overactive telomerase can lengthen telomeres until a cell becomes immortal…leading to cancer.

18 Feb 2015

TNF signaling molecule triggers Crohn's disease, ulcerative colitis

Cells lining the intestinal tract form a critical barrier, protecting our bodies from the billions of bacteria living in the gut. Breaches in this barrier are driven largely by a single signaling molecule called tumor necrosis factor (TNF), elevated amounts of which are associated with inflammatory bowel diseases like Crohn's disease and ulcerative colitis.

17 Feb 2015

UBMD physician discusses the dangers of hypothermia

The arctic cold snap affecting the Midwest and the Northeast this weekend should not be taken lightly, says David Holmes, MD, clinical associate professor of family medicine in the University at Buffalo School of Medicine and Biomedical Sciences.

17 Feb 2015

Dip a Stick test provides accurate way to detect signs of diabetes

Allie Beatty knows all too well that early detection of diabetes can significantly reduce the risk of additional complications.

16 Feb 2015

Loyola pediatrician offers tips to help ease spit-up in babies after feeding

A baby's feeding habits are a common source of questions for pediatricians. Though every baby will spit up, some do it considerably more than others, which can cause parents to think something might be wrong.

16 Feb 2015

Mesothelioma Compensation Center educates individuals about mesothelioma compensation claim

The Mesothelioma Compensation Center is doing everything possible to educate all diagnosed victims of mesothelioma and their family members about the most critical component of a mesothelioma compensation claim that, believe it or not, comes down to the skill of the lawyer advancing the claim; especially if the diagnosed victim was exposed to asbestos in the automotive manufacturing or repair industry.

13 Feb 2015

New book explores the outcomes of an aging American workforce

As chief of the Associated Press' Tokyo bureau, Joseph Coleman wrote a story about an agricultural cooperative in southwestern Japan where organizers put aging residents to work selling leaves and flowers as seasonal garnishes for high-class restaurants.

4 Feb 2015

Iovate Health Sciences International introduces StrongGirl supplements for women

Iovate Health Sciences International has introduced StrongGirl, a new line of supplements created by women for women. Every StrongGirl product is formulated to deliver on the StrongGirl promise: StrongGirl supplements are designed to help the active woman achieve her goals and be the best version of herself, with premium nutrition and effective formulas to help her be beautiful and strong, both inside and out.

3 Feb 2015

TCGA researchers uncover differences between tumors with and without HPV infection

The study by The Cancer Genome Atlas (TCGA) researchers analyzed the genomes of 279 head and neck cancer tumors. They identified subtypes of head and neck cancer based on their genomic characteristics, changes in smoking-related tumors, as well as genomic differences in head and neck cancer tumors linked to HPV, the most commonly sexually transmitted disease in the United States.

31 Jan 2015

Voices of loved ones telling familiar stories can help awaken unconscious brain, speed coma recovery

"Can he hear me?" family members are desperate to know when a loved one with a traumatic brain injury is in a coma.

23 Jan 2015

CSHL researchers describe new pathway that controls fear memories in the mouse brain

Some people have no fear, like that 17-year-old kid who drives like a maniac. But for the nearly 40 million adults who suffer from anxiety disorders, an overabundance of fear rules their lives. Debilitating anxiety prevents them from participating in life's most mundane moments, from driving a car to riding in an elevator.

20 Jan 2015

Tiny lumps of calcium phosphate may trigger age-related macular degeneration

New research from scientists at the University of Maryland School of Medicine has found that tiny lumps of calcium phosphate may be an important triggering factor for age-related macular degeneration (AMD), a degenerative eye disease that can cause severe vision loss and blindness.

20 Jan 2015

CAR T-cell therapy enters into Phase I clinical trial

Cancer fighting chimeric antigen receptor (CAR) T cells, developed in the Sentman laboratory of Dartmouth's Norris Cotton Cancer Center, are taking the next step into a Phase I clinical trial beginning early in 2015.

15 Jan 2015

Chimeric Antigen Receptor News and Research

New injectable polymer could strengthen blood clots

Repeatedly exposing children to secondhand smoke is child abuse, argues Adam Goldstein

In-car alarm could reduce crashes for young and old drivers

Wings for Life World Run to fund breakthrough clinical study on spinal cord injury

Researchers one step closer to unraveling complex processes crucial to sperm development

Neuroscientists find new pathway that allows several brain areas communicate within striatum

Study results pave way for new clinical trial for glioblastoma patients

Findings may help doctors recommend appropriate treatments, improve patient outcomes

TNF signaling molecule triggers Crohn's disease, ulcerative colitis

UBMD physician discusses the dangers of hypothermia

Dip a Stick test provides accurate way to detect signs of diabetes

Loyola pediatrician offers tips to help ease spit-up in babies after feeding

Mesothelioma Compensation Center educates individuals about mesothelioma compensation claim

New book explores the outcomes of an aging American workforce

Iovate Health Sciences International introduces StrongGirl supplements for women

TCGA researchers uncover differences between tumors with and without HPV infection

Voices of loved ones telling familiar stories can help awaken unconscious brain, speed coma recovery

CSHL researchers describe new pathway that controls fear memories in the mouse brain

Tiny lumps of calcium phosphate may trigger age-related macular degeneration

CAR T-cell therapy enters into Phase I clinical trial

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