Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

A recent study in the Journal of Biomedical Science examines the critical role of ACE2, an enzyme involved in blood volume and electrolyte balance, in chronic diseases like cardiovascular conditions, diabetes, and COVID-19. The research suggests that ACE2 could serve as both a disease severity biomarker and a therapeutic target.

28 Aug 2023

Trial addresses the optimal timing for complete revascularization of patients with STEMI and multivessel disease

Immediate multivessel percutaneous coronary intervention (PCI) is non-inferior to staged multivessel PCI for reducing death and ischaemic events in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Acoramidis shows potential to be effective, safe treatment for transthyretin amyloid cardiomyopathy

Acoramidis improves outcomes in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Ablation more effective than medical therapy in patients with end-stage heart failure, study shows

Atrial fibrillation ablation is associated with lower rates of death, urgent heart transplantation or left ventricular assist device (LVAD) implantation compared with medical therapy in patients with end-stage heart failure, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

CRT-D upgrade reduces morbidity and mortality in HFrEF patients with RV pacing

Upgrade to cardiac resynchronization therapy with a defibrillator (CRT-D) reduces morbidity and mortality and improves left ventricular (LV) reverse remodeling compared to an implantable cardioverter-defibrillator (ICD) in select patients with heart failure and reduced ejection fraction (HFrEF) and intermittent or permanent right ventricular (RV) pacing, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Intravenous ferric carboxymaltose linked to lower risk of heart failure hospitalizations in iron-deficient patients

In iron-deficient patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, intravenous ferric carboxymaltose (FCM) is associated with a reduced risk of the composite outcome of total cardiovascular hospitalization and cardiovascular death through 52 weeks compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

PROFID EHRA trial to assess the potential benefit of ICD therapy in myocardial infarction survivors

Is the routine implantation of an implantable cardioverter defibrillator (ICD) in myocardial infarction survivors with heart failure still an adequate therapy for prevention of sudden cardiac death?

28 Aug 2023

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.

28 Aug 2023

Study shows benefit of traditional Chinese medicine for heart failure

The traditional Chinese medicine qiliqiangxin reduces hospitalization for heart failure and cardiovascular death in patients with heart failure and a reduced ejection fraction (HFrEF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Texas Heart Institute receives $2 million NIH grant to develop transplantable bioartificial hearts

The Texas Heart Institute recently received a five-year, $2 million grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to advance the technology supporting development of transplantable bioartificial hearts.

25 Aug 2023

Total hip arthroplasty in nonagenarians: Risks and benefits

Potentially modifiable comorbid conditions and complications have a major impact on the risks of total hip arthroplasty (THA) for people in their nineties, reports a study in The Journal of Bone & Joint Surgery.

25 Aug 2023

Focused update of ESC Heart Failure Guidelines integrates latest evidence-based treatments

A focused update of the European Society of Cardiology (ESC) Heart Failure Guidelines is published online today in European Heart Journal following the results of major new trials that should change the management of patients with heart failure.

25 Aug 2023

NOAH-AFNET 6 trial: Oral anticoagulation not recommended for patients with atrial high rate episodes

Blood thinners (anticoagulants) cause bleeding without preventing stroke in patients with atrial high rate episodes (AHRE), but without electrocardiogram (ECG)-diagnosed atrial fibrillation, according to late breaking research presented in a Hot Line session today at ESC Congress 2023 and simultaneously published in the New England Journal of Medicine.

25 Aug 2023

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Colchicine does not significantly reduce perioperative atrial fibrillation (AF) or myocardial injury after non-cardiac surgery (MINS) in patients undergoing major non-cardiac thoracic surgery, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

ESC statement: Competency-based cardiac imaging delivery needed for effective patient care

Competency-based cardiac imaging delivery is needed for effective and efficient patient care, according to a European Society of Cardiology (ESC) statement published today in European Heart Journal, a journal of the ESC.

25 Aug 2023

Patients with heart conditions should practice good hygiene to prevent infective endocarditis

Patients with specific cardiac conditions such as valvular heart disease and congenital abnormalities, or those requiring a pacemaker, should practice good dental and skin hygiene to help prevent rare but potentially deadly infections of the heart's inner lining and valves, according to European Society of Cardiology (ESC) Guidelines on infective endocarditis, published online today in European Heart Journal.

25 Aug 2023

Semaglutide could be a game-changer for patients with HFpEF and obesity

Semaglutide improves heart failure-related symptoms and physical function and results in greater weight loss compared with placebo in patients with heart failure with preserved ejection fraction (HFpEF) and obesity, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

Heart Failure News and Research

Further Reading

Unlocking ACE2: The enzyme that links COVID-19, heart disease, and diabetes

Trial addresses the optimal timing for complete revascularization of patients with STEMI and multivessel disease

Acoramidis shows potential to be effective, safe treatment for transthyretin amyloid cardiomyopathy

Ablation more effective than medical therapy in patients with end-stage heart failure, study shows

CRT-D upgrade reduces morbidity and mortality in HFrEF patients with RV pacing

Intravenous ferric carboxymaltose linked to lower risk of heart failure hospitalizations in iron-deficient patients

PROFID EHRA trial to assess the potential benefit of ICD therapy in myocardial infarction survivors

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

Study shows benefit of traditional Chinese medicine for heart failure

Texas Heart Institute receives $2 million NIH grant to develop transplantable bioartificial hearts

Total hip arthroplasty in nonagenarians: Risks and benefits

Focused update of ESC Heart Failure Guidelines integrates latest evidence-based treatments

NOAH-AFNET 6 trial: Oral anticoagulation not recommended for patients with atrial high rate episodes

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

ESC statement: Competency-based cardiac imaging delivery needed for effective patient care

Patients with heart conditions should practice good hygiene to prevent infective endocarditis

Semaglutide could be a game-changer for patients with HFpEF and obesity

New ESC Guidelines for the management of cardiovascular disease in patients with diabetes released

Cardio or cerebrovascular mortality of AF patients has declined in the UK over 16 years

New ESC Guidelines on cardiomyopathies published online today

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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