Genes News and Research

RSS

New small molecules offer promising new way to treat autoinflammatory diseases

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory diseases.

4 Jul 2018

Study explains why men are more at risk for neurodevelopmental disorders

A new study has shed light on the reason why males are more at risk than females for neurodevelopmental disorders such as autism, schizophrenia and ADHD.

4 Jul 2018

Natural selection may have influence on personalities, suggests study

For more than a century, scientists have understood that natural selection have profound effects on how an animal looks - Anolis lizards that spend more time on the ground, for example, might need longer legs for running, while species that remain in the trees usually have shorter legs better suited for climbing.

4 Jul 2018

Study explores impact of surgeons on genetic testing in breast cancer patients

For many women diagnosed with breast cancer, genetic testing can offer important information that might guide treatment choices. But studies have shown that only about half of women who could benefit receive genetic testing.

4 Jul 2018

Daily coffee could contribute to longevity finds study

A new study published this week in the journal JAMA Internal Medicine has found evidence that moderate amounts of coffee a day can improve longevity. This latest large study stretched over a decade and included around half a million people between ages 38 and 73 years from England, Wales and Scotland.

4 Jul 2018

People with exposure to paint or other solvents more likely to develop MS

People who have been exposed to paint, varnish and other solvents and who also carry genes that make them more susceptible to developing multiple sclerosis may be at much greater risk of developing the disease than people who have only the exposure to solvents or the MS genes, according to a study published in the July 3, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 Jul 2018

New computational strategy used to identify genes associated with childhood cancer

Using a new computational strategy, researchers at UT Southwestern Medical Center have identified 29 genetic changes that can contribute to rhabdomyosarcoma, an aggressive childhood cancer.

3 Jul 2018

Researchers find new metabolic vulnerability in small cell lung cancer

Researchers at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in small cell lung cancer (SCLC) that can be targeted by existing drug therapies.

3 Jul 2018

Study does not find causal association between assisted reproduction and ovarian cancer risk

Following concerns over many years that hormonal stimulation of the ovaries necessary for IVF may increase the risk of ovarian cancer, a nationwide cohort study from Denmark has now concluded that any perceived increase in risk is actually a statistical bias resulting from vigilant diagnosis at the time of treatment.

3 Jul 2018

Researchers develop switch that can control genome editing

Researchers have developed a biological switch that reliably triggers protein expression and enables the control of genome editing tools.

3 Jul 2018

New blood test can help determine the state of a person's internal clock

With a new blood test, researchers at the Charité - Universitätsmedizin Berlin can determine the state of the internal clock of a person. Once the internal rhythm of patient is known, drugs could be administered at particular times of day making them more effective and with fewer side effects than standard therapy.

2 Jul 2018

Discovery may be key to directly reprogram non-neuronal cells into neurons

It was already in 2012 that a team of scientists headed by Professor Benedikt Berninger first succeeded in reprogramming connective tissue cells present in the brain into neurons.

2 Jul 2018

Cilia appears to play key role in formation of melanoma

Most cells in the human body have a cilium, a slender cell protuberance that picks up signals from the cell's external environment.

2 Jul 2018

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that Japan's Pharmaceuticals and Medical Devices Agency has approved LYNPARZA tablets for use in patients with unresectable or recurrent BRCA-mutated, human epidermal growth factor receptor 2 -negative breast cancer who have received prior chemotherapy.

2 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Researchers discover gene that plays role in regulating body's immune response to infection

Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease.

2 Jul 2018

Individuals may react differently to environmental chemicals based upon genetic profile

Why do individuals respond differently to the same environment? Researchers from North Carolina State University and Oregon State University have pinpointed a genetic difference in zebrafish tied to differing responses to the same environmental chemical.

30 Jun 2018

Study: Administration of endocrine disruptor causes epigenetic changes in pregnant sow's DNA

The public debate on endocrine disrupting chemicals- exogenous substances that have the same or similar effects as endogenous hormones - has been going on for some time.

30 Jun 2018

Research shows why new cancer therapies fail to work on some patients

University of Otago research provides insights into an underlying mechanism that could explain why new cancer therapies to help treat metastatic melanoma do not always work on patients, paving the way for predicting which patients will benefit from certain drugs.

30 Jun 2018

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

James McNew's and Michael Stern's biochemical hunt for the root cause of a rare, paralyzing genetic disorder is a 10-year quest that's taken an unexpected turn toward everyday killers such as Alzheimer's disease, cancer and aging.

30 Jun 2018