Laboratory News and Research

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FDA-approved anti-inflammatory drug delays onset of ALS in mice

The cause of amyotrophic lateral sclerosis (ALS)--a disabling neurodegenerative disease that affects nerve cells in the brain and spinal cord and leads to weakened muscles and early death--is not fully understood, but accumulating evidence suggests that inflammatory processes may play a role in the initiation and progression of the condition.

27 Nov 2019

Hibernators reveal genetic clues to better understand and treat obesity, metabolic disorders

Hibernation is one of nature's strangest quirks, inducing bears and other mammals to pack on massive weight- amounts that would be unhealthy for humans - so they can survive months of slumber. Yet when these animals reemerge, they are as fit as ever.

27 Nov 2019

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy.

26 Nov 2019

Novel diagnostic method for rapid measurement of celiac disease antibodies

Point-of-care testing is a rapidly growing sector, bringing medical testing from central laboratories to where the patient is receiving care.

26 Nov 2019

Looking for the source: new routes for allergy treatment

A new multinational study has reported a very full account of the B lymphocytes that produce group E antibodies, also called IgE (Immunoglobulin E), that are behind allergic reactions, which are common in up to a third of the world’s population.

26 Nov 2019

Cleveland-based startup will use federal grant to develop AI tools for TB detection

Cleveland--Diascopic LLC, a Cleveland-based medical research company that develops diagnostic technology, will use a highly competitive federal grant to develop and apply new artificial intelligence and digital pathology tools for detecting tuberculosis.

26 Nov 2019

Study reveals novel pathway to target colorectal cancer

While the emergence of precision medicine and immunotherapy has greatly improved outcomes for patients with colorectal cancer, new approaches are still needed for patients with late-stage disease who do not respond to these therapies.

26 Nov 2019

Space travel can affect intestinal function of astronauts

Bacteria, fungi, and viruses can enter our gut through the food we eat. Fortunately, the epithelial cells that line our intestines serve as a robust barrier to prevent these microorganisms from invading the rest of our bodies.

26 Nov 2019

Few things to know before buying at-home genetic testing kits

At-home genetic testing kits, also known as direct-to-consumer or lab-to-consumer DNA tests, are growing in popularity - especially as holiday gifts.

26 Nov 2019

Researchers find pupillary changes in high-school athletes after high-acceleration head impacts

Researchers from the University of Michigan found significant pupillary changes in high-school football athletes after they had sustained a high-acceleration head impact.

26 Nov 2019

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Scientists have determined that La Crosse virus, which can cause inflammation of the brain, or encephalitis, in children, affects brain cells differently depending on their developmental stage.

26 Nov 2019

Splicing factor enhances ability of triple negative breast cancers to grow and metastasize

If your DNA is a cookbook, a single gene is a recipe. But it's a flexible recipe that if edited one way can make a pie; edited another way can make a cake. And that difference can mean cancer, as a team of researchers who looked at those gene editors writes in the 26 November issue of Cell Reports.

26 Nov 2019

Stem cells do not take the day off on national holidays

While most of us are stuffing ourselves with turkey and pumpkin pie at home on Thanksgiving Day, the staff at one Cedars-Sinai laboratory will be on the job, feeding stem cells.

26 Nov 2019

A large library of products derived from fungi could help find new drugs

An enormous library of products derived from more than ten thousand fungi could help us find new drugs.

26 Nov 2019

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Hops compounds may combat metabolic syndrome by changing the gut microbiome

Compounds from hops may combat metabolic syndrome by changing the gut microbiome and altering the metabolism of acids produced in the liver, new research at Oregon State University suggests.

26 Nov 2019

GN Corporation granted Indian patent for novel corneal cell transplantation using nano-composite gel sheet

A novel cell transplantation method to treat corneal endothelial diseases such as bullous keratopathy using a nano-composite gel sheet developed by Japanese scientists was granted Indian patent to GN Corporation (GNC), Japan.

26 Nov 2019

Video games poised to fundamentally change cardiology training

Video games are a popular form of entertainment in the U.S. with more than 164 million adults playing them. Seventy-five percent of households have at least one gamer.

25 Nov 2019

New electrochemical CRISPR biosensor can help improve diagnosis of diseases

The CRISPR/Cas technology can do more than alter genes. A research team at the University of Freiburg is using what are known as gene scissors - which scientists can use to edit genetic material - in order to better diagnose diseases such as cancer.

25 Nov 2019

Dreams can help us react better to frightening situations

Do bad dreams serve a real purpose? To answer this question, researchers from the University of Geneva and University Hospitals of Geneva, Switzerland, - working in collaboration with the University of Wisconsin (USA) - analyzed the dreams of a number of people and identified which areas of the brain were activated when they experienced fear in their dreams.

25 Nov 2019

Laboratory News and Research

FDA-approved anti-inflammatory drug delays onset of ALS in mice

Hibernators reveal genetic clues to better understand and treat obesity, metabolic disorders

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Novel diagnostic method for rapid measurement of celiac disease antibodies

Looking for the source: new routes for allergy treatment

Cleveland-based startup will use federal grant to develop AI tools for TB detection

Study reveals novel pathway to target colorectal cancer

Space travel can affect intestinal function of astronauts

Few things to know before buying at-home genetic testing kits

Researchers find pupillary changes in high-school athletes after high-acceleration head impacts

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Splicing factor enhances ability of triple negative breast cancers to grow and metastasize

Stem cells do not take the day off on national holidays

A large library of products derived from fungi could help find new drugs

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Hops compounds may combat metabolic syndrome by changing the gut microbiome

GN Corporation granted Indian patent for novel corneal cell transplantation using nano-composite gel sheet

Video games poised to fundamentally change cardiology training

New electrochemical CRISPR biosensor can help improve diagnosis of diseases

Dreams can help us react better to frightening situations

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