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Researchers map how staph infections alter immune system

Infectious disease specialists at UT Southwestern Medical Center have mapped the gene profiles of children with severe Staphylococcus aureus infections, providing crucial insight into how the human immune system is programmed to respond to this pathogen and opening new doors for improved therapeutic interventions.

14 Jul 2009

Overcoming the big ‘nanotech’ challenges

Whether in the fields of medicine, sustainable energy supply or environmental protection, without making use of nanotechnology we will not be capable of overcoming the challenges which the future presents. In parallel with these efforts, though, it is essential that we examine the new technology very carefully for potential risks, such as those presented by free nanoparticles.

14 Jul 2009

By manipulating oxygen, scientists coax bacteria into a wave

Bacteria know that they are too small to make an impact individually. So they wait, they multiply, and then they engage in behaviors that are only successful when all cells participate in unison. There are hundreds of behaviors that bacteria carry out in such communities. Now researchers at Rockefeller University have discovered one that has never been observed or described before in a living system.

13 Jul 2009

Oral bacteria may contribute to the development of obesity

The world-wide explosion of overweight people has been called an epidemic. The inflammatory nature of obesity is widely recognized. Could it really be an epidemic involving an infectious agent? In this climate of concern over the increasing prevalence of overweight conditions in our society, investigators have focused on the possible role of oral bacteria as a potential direct contributor to obesity.

9 Jul 2009

One secret to how tuberculosis resists the host immune system

Mycobacterium tuberculosis is arguably the world's most successful infectious agent because it knows how to avoid elimination by slowing its own growth to a crawl. Now, a report in the July 10 issue of the journal Cell, a Cell Press publication, offers new insight into the bugs' talent for meager living.

9 Jul 2009

Innovative study brings us closer to an explanation for Crohn's disease

Twenty-five per cent of Crohn's disease patients have a mutation in what is called the NOD2 gene, but it is not precisely known how this mutation influences the disease.

9 Jul 2009

Brain's immune system may cause chronic seizures

Chronic seizures caused by traumatic head injuries may result from chemicals released by the brain's immune system attempting to repair the injured site, according to a study led by the University of Colorado at Boulder.

6 Jul 2009

Biological warfare in bacteria offers hope for new antibiotics

Scientists are to study a group of proteins that are highly effective at killing bacteria and which could hold the key to developing new types of antibiotics.

2 Jul 2009

Researchers develop new method for better diagnostic of diarrhea causing bacteria

Researchers from Helmholtz Centre for Infection Research, Germany, develop new method for better diagnostic of diarrhea causing bacteria.

30 Jun 2009

Carbon nanotubes continue to show promise in battle against cancer

Carbon nanotubes, one of the original engineered nanomaterials, also may prove to be among the most versatile, as numerous teams of investigators continue to develop novel nanotube-based therapeutic and diagnostic tools. Over the past month, three new research papers have highlighted the potential of nanotubes as weapons against cancer.

28 Jun 2009

Antibiotic prescribing should be standardized across Europe to help tackle resistance

Antibiotic prescribing for respiratory illnesses should be standardised across Europe to help reduce inappropriate prescribing and resistance, say experts in a study published on bmj.com.

24 Jun 2009

Microbial and maternal influences on allergic sensitization during childhood

When infected, the body has two types of immune defence to deploy - innate immunity and acquired immunity. In her dissertation, Shanie Saghafian Hedengren studies monocytes, a type of white blood corpuscles that are part of the innate immune system.

23 Jun 2009

Do viruses make bacteria more deadly?

In England and Wales, the national health statistics in 2007 showed that there were 8,324 death certificates which named Clostridium difficile. This is a bacterium which causes severe diarrhoea in humans and animals as the underlying cause of death, a 28% increase from 2006.

22 Jun 2009

Tibotec, TB Alliance join to expedite development of promising tuberculosis drug

The pharmaceutical company Tibotec said it will join with the non-profit Global Alliance for Tuberculosis Development (TB Alliance) to speed up the development of the experimental TB drug TMC207, Health-e/IOL reports (Thom, Health-e/IOL, 6/18). Tibotec, which is a subsidiary of Johnson & Johnson, announced the news on Wednesday at the Pacific Health Summit in Seattle (Doughton, Seattle Times, 6/18).

18 Jun 2009

Antibiotics diminish diversity of helpful gutmicrobes

It's common knowledge that a protective navy of bacteria normally floats in our intestinal tracts. Antibiotics at least temporarily disturb the normal balance. But it's unclear which antibiotics are the most disruptive, and if the full array of "good bacteria" return promptly or remain altered for some time.

18 Jun 2009

Honey more effective than antibiotics

In the first study of its kind University of Sydney researchers have found proof that some honeys can be more effective than antibiotics in treating surface wounds and infections.

17 Jun 2009

Plant microbe shares features with drug-resistant pathogen - implications for biotech

An international team of scientists has discovered extensive similarities between a strain of bacteria commonly associated with plants and one increasingly linked to opportunistic infections in hospital patients. The findings suggest caution in the use of the plant-associated strain for a range of biotech applications. The genetic analysis was conducted in part at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, and will be published in the July 2009 issue of Nature Reviews Microbiology, now available online.

16 Jun 2009

High-tech approach to combat sepsis

When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread.

15 Jun 2009

Rhinosinusitis may be a factor in toxic shock syndrome in children

Rhinosinusitis (infection and inflammation in the sinus passages surrounding the nose) appears to be a primary factor in about one-fifth of toxic shock syndrome cases in children, according to a report in the June issue of Archives of Otolaryngology-Head & Neck Surgery.

15 Jun 2009

Discovery shows potential for new severe asthma treatment

Scientists from King's College London and Imperial College London believe they have discovered a key element in the development of chronic asthma. Their research has been published in a new paper in the journal Proceedings of the National Academy of Sciences to explain why the structure and function of asthmatic airways are changed or ''remodelled'' and how this contributes to chronic asthma.

15 Jun 2009