Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Novel cancer-driving mutation discovered in vast non-coding regions of the cancer genome

An Ontario-led research group has discovered a novel cancer-driving mutation in the vast non-coding regions of the human cancer genome, also known as the "dark matter" of human cancer DNA.

9 Oct 2019

Scientists demonstrate potential method for treating advanced liver cancers

Liver cancer is the second leading cause of cancer-related deaths worldwide. The most common primary liver cancer in adults is known as hepatocellular carcinoma (HCC), and accounts for approximately 780,000 deaths every year.

9 Oct 2019

New understanding of breast cancer metastasis to bone

In breast cancer patients with metastatic disease, bone is the most common site of metastasis and the most common site of first distant relapse, with roughly half (48%) of breast cancer patients developing bone metastases after treatment.

8 Oct 2019

New insight into meningioma - possibility of targeted therapy

A new study published in the journal Oncotarget shows that certain mutations in the brain tumor called meningioma may help identify patients who have a better chance of recovery. This could help physicians make better clinical decisions based on more accurate diagnoses. It has also unveiled some of the genes that go wrong in meningiomas, as well as showing how targeted therapy could one day help fight this tumor.

7 Oct 2019

Research provides new insights into tumorigenesis of meningioma

The identification of oncogenic mutations has provided further insights into the tumorigenesis of meningioma and the possibility of targeted therapy.

5 Oct 2019

Researchers create pain mediator profile for pancreatic diseases

In a recent study, a team at the Technical University of Munich (TUM) discovered the cause of this phenomenon for the first time: a particular neuroenzyme in the body is present in the nerves of the organ in high concentrations.

2 Oct 2019

Novel immunotherapy combination could provide fresh hope for patients with cervical cancer

With an estimated 570,000 cases and 311,000 deaths in 2018 worldwide, cervical cancer currently ranks as the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women.

30 Sep 2019

PARP inhibitor combined with chemotherapy increases survival for newly diagnosed ovarian cancer patients

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that initial treatment with the PARP inhibitor veliparib in combination with chemotherapy significantly increased progression-free survival for patients with newly diagnosed, metastatic high-grade serous ovarian cancer, according to the results of the VELIA trial.

28 Sep 2019

Leukemia drug appears to be effective in treating deadly pediatric brain tumor

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional team led by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego.

21 Sep 2019

Low-dose aspirin may improve survival in patients with head and neck, lung cancers

What if a drug that sits in nearly everyone's medicine cabinet could help extend the lives of some cancer patients? In companion presentations at the American Society for Therapeutic Radiation Oncology Annual Meeting in Chicago, doctors from Roswell Park Comprehensive Cancer Center report new evidence that low-dose aspirin and other anti-inflammatories may improve survival in patients undergoing treatment for some head/neck and lung cancers.

19 Sep 2019

Artificial intelligence helps improve diagnosis of head and neck cancers

Researchers from Charité - Universitätsmedizin Berlin and the German Cancer Consortium have successfully solved a longstanding problem in the diagnosis of head and neck cancers.

12 Sep 2019

Cell adhesion protein promotes metastasis in breast cancer, study reveals

Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis.

From Johns Hopkins Medicine 11 Sep 2019

Study confirms effectiveness of a combination therapy for advanced liver cancer

Liver cancer affects hundreds of thousands of people annually, and there are few viable therapies for the advanced stages of its most common form--hepatocellular carcinoma.

6 Sep 2019

Study links FAK protein to chemotherapy resistance in ovarian cancer

Although the number of women being diagnosed and dying of ovarian cancer is declining, recurrence, drug resistance and mortality remain high for women with high-grade serous ovarian carcinoma, the most common form of epithelial ovarian cancer.

3 Sep 2019

Study on national burden of HPV-associated oropharyngeal head and neck cancers in the U.S.

Over the last two decades, there has been a rise in head and neck cancers in the oropharynx, a region in the back of the throat that includes the tonsils and the base of the tongue.

29 Aug 2019

New study provides a better understanding of Merkel cell carcinoma

Merkel cell carcinoma is a rare and aggressive type of skin cancer. Also called neuroendocrine carcinoma of the skin, it is much less common than most other types of skin cancer. But, it’s one of the most dangerous types since it’s more likely to spread to the other parts of the body.

21 Aug 2019

Study identifies key epigenetic regulator that controls skin cell turnover

The outer layer of the skin completely replaces itself every two to four weeks, but when this process is blocked, cancer can grow.

21 Aug 2019

Largest genomic analysis could help improve treatment for Merkel cell carcinoma patients

Merkel cell carcinoma is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each year in the United States.

20 Aug 2019

Mice study suggests anti-cancer effect of ketogenic diet

It's well known that keeping blood glucose levels in check can help individuals avoid or manage diabetes, but new research led by biologists at The University of Texas at Dallas suggests that restricting blood glucose levels might also keep certain cancers at bay.

13 Aug 2019

Human apolipoprotein E promotes hepatitis B virus infection

Human apolipoprotein E (apoE) promotes hepatitis B virus (HBV) infection and production, according to a study published DATE in the open-access journal PLOS Pathogens by Luhua Qiao and Guangxiang (George) Luo of the University of Alabama at Birmingham School of Medicine.

From PLOS ONE 13 Aug 2019