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Can falsified or substandard antimicrobials increase antimicrobial resistance?

The association between substandard or falsified (SF) antibiotics and antimicrobial resistance (AMR).

5 Oct 2023

New device simulates human diseases in multiple organs

Imagine a device smaller than a toddler's shoebox that can simulate any human disease in multiple organs or test new drugs without ever entering - or harming - the body.

4 Oct 2023

Breakthrough technique could one day provide tailored repairs for people with brain injuries

A breakthrough technique developed by University of Oxford researchers could one day provide tailored repairs for those who suffer brain injuries.

4 Oct 2023

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Researchers developed the ATRIVIEW® platform to screen for molecules that promote differentiation neural stem cells (NSCs).

4 Oct 2023

Study identifies potential drug target for lymphedema

The human lymphatic system consists of a vast network of vessels that drain protein-rich fluid in tissues and transport it to lymph nodes.

3 Oct 2023

Genetic testing of one thousand embryos provides insights into human development and IVF

By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.

3 Oct 2023

Could dark chocolate improve the gut health of athletes?

The effect of cocoa polyphenols on intestinal permeability.

3 Oct 2023

Could seaweeds be the superfood and medicine of the future?

Researchers consolidate the diverse nutritional and medicinal benefits of seaweeds, touting their potential in food, nutraceuticals, and pharmaceuticals. The study also highlights challenges and opportunities in industrial applications, calling for more research to optimize extraction and refinement processes.

2 Oct 2023

Ginger shows promise as a natural defense against autoimmune diseases

Comprehensive study reveals that whole ginger extracts have a significant impact on inhibiting neutrophil hyperactivity, a key factor in autoimmune diseases like APS and lupus. Consuming ginger for just a week showed promising results in both animal models and human trials, positioning it as a natural and affordable treatment option for a range of autoimmune disorders.

2 Oct 2023

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

A new tau PET radiotracer, 18F-SNFT-1, has been found to be more effective than existing tau PET radiotracers in identifying Alzheimer's disease in its earliest stages, according to research published in the September issue of The Journal of Nuclear Medicine.

29 Sep 2023

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Researchers from the University of Texas Southwestern have developed an aerosolized, mutated form of ACE2 that effectively neutralizes various SARS-CoV-2 variants in both cell cultures and mice. The study suggests that this modified ACE2 has promising preventive and therapeutic potential against COVID-19, especially with its easy aerosolized administration.

28 Sep 2023

Bioengineered human stomach micro-physiological system reveals unseen defense mechanisms

A groundbreaking development in biomedical engineering has led to the creation of a human stomach micro-physiological system (hsMPS), representing a significant leap forward in understanding and treating various gastrointestinal diseases, including stomach cancer.

28 Sep 2023

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Researchers explored the therapeutic impact of Thiostrepton on experimental colitis by examining its effects on colon inflammation and determining its targets through various biochemical approaches.

28 Sep 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Researchers used an interdisciplinary approach incorporating phylogenetics, 3D protein modeling, and plasmid design to identify and computationally design an antigen representing the core of most currently known sarbecoviruses.

27 Sep 2023

Skin under pressure: tension affects skin's reaction to pollution

Researchers ratified previous findings that ozone (O3) exposure (an air pollutant) alters the antimicrobial peptide expression in the skin with and without tension.

27 Sep 2023

Could a mushroom-derived product be the future of lung cancer prevention?

Researchers find that a mushroom-derived product, GLSF, shows promise in reducing lung toxicity and tumor development induced by tobacco smoke carcinogens in mice. The study opens the door for future clinical trials, potentially offering a natural preventive measure against lung cancer.

26 Sep 2023

Study aims to cast light on the impact of combined alcohol and e-cigarette use on blood brain barrier

With a variety of flavors and widespread perceptions of safety, e-cigarettes appeal to an array of users and especially to adolescents. E-cigarette use, however, is linked to increased alcohol consumption, as well as the use of other substances and drugs.

26 Sep 2023

Key player in ovarian cancer may have implications for PCOS

Researchers explore the involvement and altered expression of BBOX1-AS1 and microRNA-19b in polycystic ovary syndrome.

26 Sep 2023

How cleansers and moisturizers make your skin feel tight or soft

Some cleansers make the skin feel "tight" and some moisturizers make the skin feel "soft." Reinhold H. Dauskardt and colleagues traced the mechanisms by which applying cleansers or moisturizers to the skin results in such sensations, using in-vitro biomechanical testing, computational neural stimulation modeling, and self-assessment surveys completed by thousands of participants.

26 Sep 2023

in vitro News and Research

Can falsified or substandard antimicrobials increase antimicrobial resistance?

New device simulates human diseases in multiple organs

Breakthrough technique could one day provide tailored repairs for people with brain injuries

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Study identifies potential drug target for lymphedema

Genetic testing of one thousand embryos provides insights into human development and IVF

Could dark chocolate improve the gut health of athletes?

Could seaweeds be the superfood and medicine of the future?

Ginger shows promise as a natural defense against autoimmune diseases

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Bioengineered human stomach micro-physiological system reveals unseen defense mechanisms

Natural antibiotic thiostrepton reveals new hope for inflammatory bowel disease treatment

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Skin under pressure: tension affects skin's reaction to pollution

Could a mushroom-derived product be the future of lung cancer prevention?

Study aims to cast light on the impact of combined alcohol and e-cigarette use on blood brain barrier

Key player in ovarian cancer may have implications for PCOS

How cleansers and moisturizers make your skin feel tight or soft

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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