Androgen News and Research

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Researchers uncover mechanism fueling prostate cancer

Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason why a typically normal protein goes awry and fuels cancer.

9 Sep 2024

Major funding boost aims to advance research on bone metastasis in breast and prostate cancers

Breast Cancer Now and Prostate Cancer Research have joined forces to fund up to £600,000 of new research to tackle the spread of both cancers to the bones, known as bone metastasis.

6 Sep 2024

Study reveals how sex hormones regulate immune system functions

Findings indicate that testosterone therapy in trans men alters immune system responses, suggesting implications for disease susceptibility and treatment.

6 Sep 2024

Understanding the hormonal paradox in prostate cancer progression

A treatment paradox has recently come to light in prostate cancer: Blocking testosterone production halts tumor growth in early disease, while elevating the hormone can delay disease progression in patients whose disease has advanced.

4 Sep 2024

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.

29 Aug 2024

Olaparib effective against BRCA2-mutated prostate cancer

The anti-cancer drug olaparib may be effective in treating biochemically recurrent prostate cancer without accompanying hormone therapy for men who have mutations in genes such as BRCA2, according to results of a phase II clinical trial of 51 patients conducted at the Johns Hopkins Kimmel Cancer Center and three other sites.

23 Aug 2024

Robotic gait training improves mobility in patients with spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA) is a rare X-linked neuromuscular disorder that results from an abnormal expansion of gene sequences in the androgen receptor gene.

22 Aug 2024

Precision medicine enhances prostate cancer treatment with genetic profiling

Men with metastatic castration-resistant prostate cancer should be treated primarily with second-generation hormone drugs, which offer better treatment response and longer life expectancy than chemotherapy.

20 Aug 2024

New research shows how testosterone may shield against severe Covid-19

A new study has revealed important information about how a patient's testosterone level can help protect them from severe Covid-19.

9 Aug 2024

New nanoparticle-based immunotherapy delays hormone therapy resistance in prostate cancer

A new form of immunotherapy using innovative nanoparticles can delay resistance to hormone therapy and help men with prostate cancer live longer.

5 Aug 2024

Harnessing ctDNA measurements for response assessment in metastatic castration resistant prostate cancer

A new editorial paper was published in Oncotarget's Volume 15 on July 2, 2024, entitled, "Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer."

18 Jul 2024

Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer

A recent European Urology Oncology study assessed the mortality risks, based on the Gleason score and clinical parameters, in patients with prostate cancer.

11 Jul 2024

Gut bacteria-metabolized equol shows promise in cancer prevention

Researchers reviewed how soy isoflavones are metabolized by gut bacteria into equol, exploring its role in cancer prevention and treatment. They examined the molecular mechanisms and gut microbiota involved to understand equol's anti-tumor effects.

11 Jul 2024

Research reveals immune suppression link between cancer and pregnancy

To understand why some cancers successfully circumvent the immune system to grow unchecked, researchers turned to pregnancy.

8 Jul 2024

Pharmacogenomics: A pathway to personalized treatment in prostate cancer

Prostate cancer (PC) stands as the second leading cause of death among American men, with about 1 in 8 men diagnosed during their lifetime.

2 Jul 2024

Artemisinins: A new hope for women with polycystic ovary syndrome

Plant-derived compounds best known for their antimalarial properties relieve polycystic ovary syndrome, a major public health problem that affects millions of women worldwide.

13 Jun 2024

Natural antioxidants could delay age-related decline in male testosterone production

Natural polyphenolic compounds to enhance testosterone production and prevent age-related hypogonadism in aging males.

12 Jun 2024

Crinecerfont: A promising compound for reducing corticosteroid dependence in CAH patients

People born with the common form of congenital adrenal hyperplasia lack an enzyme in the adrenal glands needed to make the hormones cortisol and aldorsterone, which are involved in the body's response to stress and blood pressure regulation.

10 Jun 2024

Berotralstat: A promising oral treatment for hereditary angioedema with normal C1-inhibitor

BioCryst Pharmaceuticals, Inc. today announced new real-world evidence showing that patients with hereditary angioedema (HAE) who have normal C1-inhibitor (HAE-nC1-INH) level and function had a reduction in monthly attack rates after starting oral, once-daily berotralstat.

8 Jun 2024

Unlocking the potential of ubiquitin-proteasome system in cancer treatment

A new editorial paper was published in Oncoscience (Volume 11) on May 6, 2024, entitled, "Restoring our ubiquitination machinery to overcome resistance in cancer therapy."

7 Jun 2024