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Mayo Clinic study reveals brain cell deficit behind Tourette syndrome

A new Mayo Clinic study finds that people with Tourette syndrome have about half as many of a specific type of brain cell that helps calm overactive movement signals as people without the condition.

22 Apr 2025

Cell-by-cell analysis reveals brain changes in Tourette syndrome

In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have pinpointed exactly which cells are perturbed and how they malfunction, revealing how different types of brain cells are affected by the condition.

9 Apr 2025

Study uncovers conserved development and evolutionary innovations in the human hypothalamus

In a new study published in Developmental Cell on April 8, a research team led by Prof. WU Qingfeng at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has demonstrated the conserved cellular development and evolutionary innovations in the developing human hypothalamus.

9 Apr 2025

Experimental drug NU-9 shows promise for Alzheimer's and ALS treatment

Experimental drug NU-9 - a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) - improves neuron health in animal models of Alzheimer's disease, according to a new Northwestern University study.

8 Apr 2025

Weight training shields the brain from dementia in older adults

The benefits of weight training are many: it promotes gains in strength and muscle mass, reduces body fat, and contributes to well-being and mental health.

1 Apr 2025

New insights into how glutamate opens brain cell signaling channels

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most common signaling molecules, glutamate, opens a channel and allows a flood of charged particles to enter.

28 Mar 2025

IL-12 targeting could open pathways for new Alzheimer's treatments

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer's disease.

17 Mar 2025

New method enhances precision in monitoring brain activity during deep brain stimulation

Mayo Clinic researchers have found a new way to more precisely detect and monitor brain cell activity during deep brain stimulation, a common treatment for movement disorders such as Parkinson's disease and tremor.

14 Mar 2025

Groundbreaking stem cell therapy trial for Alzheimer's disease underway at UTHealth Houston

A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer's disease is underway at UTHealth Houston.

14 Mar 2025

High-fat diet could cause memory problems in older adults after just a few days

Just a few days of eating a diet high in saturated fat could be enough to cause memory problems and related brain inflammation in older adults, a new study in rats suggests.

6 Mar 2025

Non-invasive 40Hz gamma stimulation could help fight Alzheimer’s

A decade after scientists in The Picower Institute for Learning and Memory at MIT first began testing whether sensory stimulation of the brain's 40Hz "gamma" frequency rhythms could treat Alzheimer's disease in mice, a growing evidence base supporting the idea that it can improve brain health-in humans as well as animals-has emerged from the work of labs all over the world.

3 Mar 2025

Study reveals how air pollution contributes to Alzheimer's disease

Air pollution contributes to nearly 7 million premature deaths each year, and its effects go far beyond the lungs.

28 Feb 2025

LJI scientists discover a potential new target for treating Parkinson's disease

Scientists at La Jolla Institute for Immunology (LJI) have found a potential new target for treating Parkinson's disease.

25 Feb 2025

Cholesterol metabolite linked to Parkinson's disease development in mice

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice.

18 Feb 2025

SwRI develops computational method to track brain cell development

A team led by Southwest Research Institute (SwRI) developed a computational method to improve techniques to track brain cell development over time.

18 Feb 2025

Study sheds new light on brain evolution

In a new study published in Science, a Belgian research team explores how genetic switches controlling gene activity define brain cell types across species.

17 Feb 2025

Breakthrough discovery reveals key role of ovoid cells in object recognition memory

Take a look around your home and you'll find yourself surrounded by familiar comforts-photos of family and friends on the wall, well-worn sneakers by the door, a shelf adorned with travel mementos.

13 Feb 2025

Alzheimer’s escape: How one man defied his genetic fate for nearly two decades

A groundbreaking study reveals how a rare combination of genetics, proteomics, and environmental factors may hold the key to delaying or preventing Alzheimer's, challenging long-held assumptions about the disease.

11 Feb 2025

Experimental drug shows promise in restoring memory in Alzheimer's model

A paradigm-shifting study from the Centre for Addiction and Mental Health (CAMH) shows an experimental drug, GL-II-73, has the potential to restore memory and cognitive function in a mouse model of Alzheimer's disease.

4 Feb 2025

Researchers identify brain circuit to reduce anxiety without side effects

Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects.

28 Jan 2025