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Rubicon Genomics introduces PicoPLEX DNA-seq Kits for use with Illumina NGS platforms

Rubicon Genomics, Inc. today announced the launch of its PicoPLEX DNA-seq Kits for use with Illumina next-generation sequencing (NGS) platforms. PicoPLEX's outstanding robustness and reproducibility have made it the worldwide standard for single-cell DNA amplification for microarray and PCR-based pre-implantation genetic screening and diagnosis. PicoPLEX DNA-seq now enables researchers and clinicians to access PicoPLEX technology for analyses conducted on Illumina NGS systems.

10 Feb 2014

Researchers discover how 'entrance exam' set by womb determines if implantation of an embryo is successful

Researchers have discovered how an 'entrance exam' set by the womb determines if the implantation of an embryo is successful; potentially a milestone for advances in pregnancy treatments.

7 Feb 2014

Gladstone-led study represents important step towards cure for type 1 diabetes

A cure for type 1 diabetes has long eluded even the top experts. Not because they do not know what must be done-but because the tools did not exist to do it. But now scientists at the Gladstone Institutes, harnessing the power of regenerative medicine, have developed a technique in animal models that could replenish the very cells destroyed by the disease.

7 Feb 2014

Researchers identify histone proteins that may be key to generate induced totipotent stem cells

One major challenge in stem cell research has been to reprogram differentiated cells to a totipotent state. Researchers from RIKEN in Japan have identified a duo of histone proteins that dramatically enhance the generation of induced pluripotent stem cells (iPS cells) and may be the key to generating induced totipotent stem cells.

7 Feb 2014

Neuroscientist, researchers receive Vilcek Prize in Biomedical Science

The Vilcek Foundation is pleased to name Thomas M. Jessell as the winner of the 2014 Vilcek Prize in Biomedical Science. Awarded annually, the Vilcek Prizes honor the contributions of immigrants to the American arts and sciences, and include $100,000 cash awards.

30 Jan 2014

New method allows for large-scale generation of human embryonic stem cells

A new method allows for large-scale generation of human embryonic stem cells of high clinical quality. It also allows for production of such cells without destroying any human embryos.

27 Jan 2014

Scientists provide new insights into molecular regulation of stem cell differentiation

The findings of the scientists of the Institute of Diabetes and Regeneration Research (IDR) at Helmholtz Zentrum München (HMGU) provide new insights into the molecular regulation of stem cell differentiation.

25 Jan 2014

Researchers discover new gene involved in severe childhood epilepsy

A European consortium of epilepsy researchers has reported the discovery of a new gene involved in severe childhood epilepsy. Using a novel combination of technologies, including trio exome sequencing of patient/parental DNA and genetic studies in the tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found that mutations in the gene CHD2 are responsible for a subset of epilepsy patients with symptoms similar to Dravet syndrome - a severe form of childhood epilepsy that is in many patients resistant to currently available anti-epileptic drugs.

23 Jan 2014

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Embryonal tumours with multilayered rosettes (ETMR) are rare, deadly brain tumours that affect mainly children below the age of 4 years. There are 300 cases reported but probably there are many more as this tumour is often misdiagnosed.

21 Jan 2014

BioTime subsidiary releases version 1.5 of LifeMap Discovery

LifeMap Sciences, Inc., a subsidiary of BioTime, Inc., announced today the release of LifeMap Discovery version 1.5. LifeMap Discovery is a state-of-the-art roadmap of embryonic development and stem cell biology.

18 Jan 2014

Immune system plays important role in heart's response to injury

The immune system plays an important role in the heart's response to injury. But until recently, confusing data made it difficult to distinguish the immune factors that encourage the heart to heal following a heart attack, for example, from those that lead to further damage.

16 Jan 2014

Study shows wide-ranging variation in patterns of X chromosome inactivation in female mice

Producing brightly speckled red and green snapshots of many different tissues, Johns Hopkins researchers have color-coded cells in female mice to display which of their two X chromosomes has been made inactive, or “silenced.”

10 Jan 2014

Researcher reveals how temperature impacts development of embryos

In nature, animals face a broad range of temperatures, and at times the heat can become taxing. When it becomes too hot to survive, some animals can simply migrate to more favorable climates, but what if you are a mere embryo confined within an egg and cannot escape the heat?

6 Jan 2014

New study by bioethicists indicates patients give "broad endorsement" to iPSC research

In an early indication of lay opinions on research with induced pluripotent stem cells, which are stem cells made from skin or other tissues, a new study by bioethicists at Johns Hopkins University indicates that despite some ethical concerns, patients give the research "broad endorsement".

6 Jan 2014

Researchers study zebrafish embryo skin to find link between low calcium and colon cancer

A tiny, transparent fish embryo and a string of surprises led scientists to a deeper understanding of the perplexing link between low calcium and colon cancer.

14 Dec 2013

Polyunsaturated fatty acids play key role in embryonic development

One classical question in developmental biology is how different tissue types arise in the correct position of the developing embryo. While one signaling pathway that controls this process has been well described, unexpected findings from a team led by Carnegie's Steven Farber reveal the importance of polyunsaturated fatty acid metabolism in this process. It is published online December 12 in Developmental Cell.

13 Dec 2013

New study may pave way for more effective treatment for deadly childhood cancer

A new study by Canadian researchers may pave the way for more effective treatment of an aggressive and deadly type of brain tumour, known as ETMR/ETANTR. The tumour, which is seen only in children under four, is almost always fatal, despite aggressive treatment. The study proposes a new model for how this brain tumour develops and suggests possible targets to investigate for novel therapies.

12 Dec 2013

Father's diet before conception plays crucial role in health of offspring

Mothers get all the attention. But a study led by McGill researcher Sarah Kimmins suggests that the father's diet before conception may play an equally important role in the health of their offspring. It also raises concerns about the long-term effects of current Western diets and of food insecurity.

11 Dec 2013

Scientists devise method to measure forces in 3D tissues, living embryos

As embryonic tissue develops, cells push and pull on each other, and they must do so correctly for the tissue to develop properly. Now scientists at Harvard University have devised the first method to measure these forces in three-dimensional (3D) tissues and living embryos.

10 Dec 2013

UC Santa Barbara professor finds method for measuring cellular forces that shape tissues, organs

Like tiny construction workers, cells sculpt embryonic tissues and organs in 3D space. This task is complicated and requires constant communication between cells to coordinate their actions and generate the forces that will shape their environment into complex tissue morphologies.

10 Dec 2013

Embryo News and Research

Rubicon Genomics introduces PicoPLEX DNA-seq Kits for use with Illumina NGS platforms

Researchers discover how 'entrance exam' set by womb determines if implantation of an embryo is successful

Gladstone-led study represents important step towards cure for type 1 diabetes

Researchers identify histone proteins that may be key to generate induced totipotent stem cells

Neuroscientist, researchers receive Vilcek Prize in Biomedical Science

New method allows for large-scale generation of human embryonic stem cells

Scientists provide new insights into molecular regulation of stem cell differentiation

Researchers discover new gene involved in severe childhood epilepsy

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

BioTime subsidiary releases version 1.5 of LifeMap Discovery

Immune system plays important role in heart's response to injury

Study shows wide-ranging variation in patterns of X chromosome inactivation in female mice

Researcher reveals how temperature impacts development of embryos

New study by bioethicists indicates patients give "broad endorsement" to iPSC research

Researchers study zebrafish embryo skin to find link between low calcium and colon cancer

Polyunsaturated fatty acids play key role in embryonic development

New study may pave way for more effective treatment for deadly childhood cancer

Father's diet before conception plays crucial role in health of offspring

Scientists devise method to measure forces in 3D tissues, living embryos

UC Santa Barbara professor finds method for measuring cellular forces that shape tissues, organs

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