Microscopy News and Research

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Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

Study sheds new light on how reproduction permanently alters females’ bones

Reproduction permanently alters females' bones in ways not previously known, a team of anthropologists has found. Its discovery, based on an analysis of primates, sheds new light on how giving birth can permanently change the body.

2 Nov 2022

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

Researchers examined virus-virus interactions using human lung cells coinfected with two co-circulating respiratory infection-causing viruses, respiratory syncytial virus (RSV) and influenza A virus (IAV).

1 Nov 2022

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers demonstrated how interferon-stimulated gene 15 (ISG15) is involved in the Vaccinia virus (VACV) dissemination.

1 Nov 2022

Novel computational method maps the architecture of human tissues in unprecedented detail

Weill Cornell Medicine researchers have developed a computational method to map the architecture of human tissues in unprecedented detail. Their approach promises to accelerate studies on organ-scale cellular interactions and could enable powerful new diagnostic strategies for a wide range of diseases.

1 Nov 2022

Researchers use deep neural networks to virtually stain microscopic images of unlabeled tissue

In the hospital, there is a group of doctors who use tissue samples as "evidence materials", analyze the evidence using knives, slicers and microscopes to extract clues from the tissue samples, and provide patients with "verdicts" - diagnostic reports.

31 Oct 2022

SpyCatcher-SpyTag technology used to develop recombinant protein-based intranasal vaccine against SARS-CoV-2

The findings of a new study showed that the intranasal SpyCage vaccine platform can be protective against SARS-CoV-2 and may prove to be a versatile and adaptable modality for the formulation of intranasal vaccines that target respiratory pathogens.

31 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

An unprecedented list of health-threatening fungi released by the WHO

The WHO fungal priority pathogens list ranks pathogens that pose a serious risk of morbidity and mortality in humans.

27 Oct 2022

Study shows the potential of experimental monoclonal antibodies to treat Epstein-Barr virus infection

A panel of investigational monoclonal antibodies (mAbs) targeting different sites of the Epstein-Barr virus (EBV) blocked infection when tested in human cells in a laboratory setting.

27 Oct 2022

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Researchers reported three human monoclonal antibodies generated from COVID-19-recovered individuals during the initial wave of the pandemic in India.

27 Oct 2022

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

A study tested the hypothesis that the ACE-2 receptor of SARS-CoV-2 is not only an attachment factor in viral infection but also plays a role in activating the viral spike protein to facilitate membrane fusion.

27 Oct 2022

Study provides a guide to neutralizing Lassa virus using a trio of rare antibodies

A new study from scientists at La Jolla Institute for Immunology (LJI) gives researchers a guide to neutralizing Lassa virus using a trio of rare antibodies isolated from survivors of Lassa virus infection.

26 Oct 2022

Researchers fabricate a non-porous biodegradable vascular graft

Researchers developed a novel small-diameter biodegradable vascular graft that aids the formation of elastin-containing structures in the intima-media, which is important for the normal functioning of the artery.

26 Oct 2022

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

Researchers evaluated imprinted antibody responses against SARS-CoV-2 Omicron sublineages.

24 Oct 2022

The performance of state-of-the-art cell segmentation algorithms on a diverse collection of bacterial cells

Researchers assessed a novel method for bacterial cell segmentation named Omnipose.

21 Oct 2022

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

Pseudomonas aeruginosa (P.a.) are resistant to most antibiotics and cause life-threatening infections of wounds or the lungs.

21 Oct 2022

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the Hepatitis C virus (HCV) and enable it to enter host cells.

20 Oct 2022

Penn State researchers lay the foundation for precision fabrication of tumor models

Researchers at Penn State have successfully 3D bioprinted breast cancer tumors and treated them in a breakthrough study to better understand the disease that is one of the leading causes of mortality worldwide.

18 Oct 2022

Deep learning software helps to identify miniscule bacteria in microscopy images

Omnipose, a deep learning software, is helping to solve the challenge of identifying varied and miniscule bacteria in microscopy images.

17 Oct 2022

Microscopy News and Research

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

Study sheds new light on how reproduction permanently alters females’ bones

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Novel computational method maps the architecture of human tissues in unprecedented detail

Researchers use deep neural networks to virtually stain microscopic images of unlabeled tissue

SpyCatcher-SpyTag technology used to develop recombinant protein-based intranasal vaccine against SARS-CoV-2

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

An unprecedented list of health-threatening fungi released by the WHO

Study shows the potential of experimental monoclonal antibodies to treat Epstein-Barr virus infection

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

Study provides a guide to neutralizing Lassa virus using a trio of rare antibodies

Researchers fabricate a non-porous biodegradable vascular graft

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

The performance of state-of-the-art cell segmentation algorithms on a diverse collection of bacterial cells

Researchers identify a natural defense mechanism that protects cells from Pseudomonas infection

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

Penn State researchers lay the foundation for precision fabrication of tumor models

Deep learning software helps to identify miniscule bacteria in microscopy images

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