Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Researchers uncover biochemical pathway that may help identify drugs to treat Alzheimer's

Researchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of beta-amyloid protein, the toxic initiator of Alzheimer's disease.

20 Feb 2019

Study finds neuromelanin-sensitive MRI as potential biomarker for psychosis

Researchers have shown that a type of magnetic resonance imaging -- called neuromelanin-sensitive MRI is a potential biomarker for psychosis.

18 Feb 2019

NIH scientists zero in on genes associated with AMD

National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration, a leading cause of vision loss and blindness among people age 65 and older.

12 Feb 2019

Researchers report promising advance in the search for new class of antidepressants

In experiments with mice, researchers at Johns Hopkins Medicine report a promising advance in the search for a new class of drugs to treat major depression.

8 Feb 2019

Understanding ‘prodromal’ phase in Parkinson’s may prevent disease from developing

In the past 25 years it has become clear that some symptoms of Parkinson's disease occur decades before the development of motor symptoms and clinical diagnosis, and that monitoring these emerging symptoms may provide important insights into the origin and development of the disease.

6 Feb 2019

Researchers link protein clusterin to many facets of cardiometabolic syndrome risk

During a study spanning nearly a decade, researchers at The Ohio State University College of Medicine, Houston Methodist Research Institute and Houston Methodist Cancer Center have linked the protein clusterin - for the first time -- to many different facets of cardiometabolic syndrome risk through its actions in the liver.

4 Feb 2019

Blood marker could aid in early prediction of Alzheimer's progression

Years before symptoms of Alzheimer's disease manifest, the brain starts changing and neurons are slowly degraded. Scientists at the German Center for Neurodegenerative Diseases, the Hertie Institute for Clinical Brain Research and the University Hospital Tuebingen now show that a protein found in the blood can be used to precisely monitor disease progression long before first clinical signs appear.

21 Jan 2019

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease - even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerative Diseases in Germany.

21 Jan 2019

Blood test detects brain damage linked to Alzheimer’s years before symptoms develop

Researchers have developed a blood test that can detect signs of brain damage among people who will develop Alzheimer’s years before the onset of memory loss.

21 Jan 2019

Defective astrocytes linked to alpha-synuclein accumulation in Parkinson's

Researchers have found that defects in brain glial cells called astrocytes are linked to the accumulation of alpha-synuclein in Parkinson's disease.

10 Jan 2019

Essential nutrient may hold promise in the war against Alzheimer's disease

In a new study, researchers at the Biodesign Institute explore a safe and simple treatment for one of the most devastating and perplexing afflictions: Alzheimer's disease.

8 Jan 2019

Study: Mice lacking PARL protein display specific problems in the nervous system reminiscent of Leigh syndrome

Leuven researchers led by professor Bart De Strooper (VIB-KU Leuven) have identified a new role for PARL, a protein that has been linked to Parkinson's disease.

3 Jan 2019

NIPER researcher presents a review on autophagy in neuronal cells

Autophagy is a cellular degradation process that can cause the death of a cell in certain conditions. Autophagy is necessary to maintain cellular homeostasis by clearing out damaged cellular organelles and proteins through certain pathways.

27 Dec 2018

European scientists aim to identify causes of dementia

Dementia is common to a variety of neurodegenerative diseases such as Alzheimer's disease, Parkinson disease and Down syndrome. This common symptom is one of the major causes of disability and dependency among older people.

19 Dec 2018

Study uncovers new genetic clues to frontotemporal dementia

Unlike the more common Alzheimer's disease, frontotemporal dementia tends to afflict young people. It accounts for an estimated 20 percent of all cases of early-onset dementia.

13 Dec 2018

Intellectually active lifestyle confers protection against neurodegeneration in Huntington's patients

Researchers from the Cognition and Brain Plasticity research group of the Bellvitge Biomedical Research Institute and the University of Barcelona, in collaboration with several hospitals, have discovered that an intellectually active lifestyle confers protection against neurodegeneration in people with Huntington's disease, delaying the onset of symptoms and loss of grey matter in the brain.

12 Dec 2018

Single tau molecule holds clues to help diagnose neurodegeneration in its earliest stages

Scientists who recently identified the molecular start of Alzheimer's disease have used that finding to determine that it should be possible to forecast which type of dementia will develop over time - a form of personalized medicine for neurodegenerative diseases.

11 Dec 2018

Researchers explore how glial cells develop in the brain from neural precursor cells

Two types of cells are active in the brain: nerve cells and glial cells. The latter have long been regarded primarily as supportive cells, but it is increasingly recognized that they play an active role in the communication between neurons in the brain.

10 Dec 2018

Mount Sinai researcher awarded $2.5 million to advance understanding of neurodegenerative diseases

Ivan Marazzi, PhD, Assistant Professor of Microbiology at the Icahn School of Medicine at Mount Sinai, was awarded $2.5 million in funding by the Chan Zuckerberg Initiative to further the understanding of the underlying causes of neurodegenerative disorders such as Lou Gehrig's, Alzheimer's, and Parkinson's diseases. The

7 Dec 2018

UT Austin researcher receives $2.5 million CZI grant for neurodegenerative disease research

Ning "Jenny" Jiang, an associate professor in the Cockrell School of Engineering's Department of Biomedical Engineering and the Dell Medical School's Department of Oncology, has been awarded a $2.5 million grant from the Chan Zuckerberg Initiative to participate in the philanthropic organization's inaugural Neurodegeneration Challenge Network.

7 Dec 2018

Neurodegeneration News and Research

Further Reading

Researchers uncover biochemical pathway that may help identify drugs to treat Alzheimer's

Study finds neuromelanin-sensitive MRI as potential biomarker for psychosis

NIH scientists zero in on genes associated with AMD

Researchers report promising advance in the search for new class of antidepressants

Understanding ‘prodromal’ phase in Parkinson’s may prevent disease from developing

Researchers link protein clusterin to many facets of cardiometabolic syndrome risk

Blood marker could aid in early prediction of Alzheimer's progression

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

Blood test detects brain damage linked to Alzheimer’s years before symptoms develop

Defective astrocytes linked to alpha-synuclein accumulation in Parkinson's

Essential nutrient may hold promise in the war against Alzheimer's disease

Study: Mice lacking PARL protein display specific problems in the nervous system reminiscent of Leigh syndrome

NIPER researcher presents a review on autophagy in neuronal cells

European scientists aim to identify causes of dementia

Study uncovers new genetic clues to frontotemporal dementia

Intellectually active lifestyle confers protection against neurodegeneration in Huntington's patients

Single tau molecule holds clues to help diagnose neurodegeneration in its earliest stages

Researchers explore how glial cells develop in the brain from neural precursor cells

Mount Sinai researcher awarded $2.5 million to advance understanding of neurodegenerative diseases

UT Austin researcher receives $2.5 million CZI grant for neurodegenerative disease research

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