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Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology, has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.

27 Feb 2024

Spirulina shows promise in battling heart disease and diabetes

Researchers show Spirulina's therapeutic benefits, including anti-inflammatory and antidiabetic properties, can significantly lower cardiovascular disease risk.

26 Feb 2024

Researchers uncover crucial role of collateral blood vessels in stroke recovery

Blood vessels that cross-connect adjacent arterial trees regulate blood flow to the brain in stroke patients.

26 Feb 2024

Study reveals how long COVID can affect brain function through vascular disruption

The neurological response to coronavirus disease 2019 (COVID-19) may be due to brain-brain barrier (BBB) disruption.

26 Feb 2024

Reevaluating the role of direct oral anticoagulants in cardiovascular treatment

Direct oral anticoagulants (DOACs) are a common treatment for patients with a wide variety of cardiovascular conditions.

23 Feb 2024

Understanding the role played by HIV in pulmonary hypertension

Across the globe, more than 39 million people are living with the Human Immunodeficiency Virus (HIV), the virus that causes AIDS, including more than 1.3 million new HIV diagnoses last year.

23 Feb 2024

Some stroke patients experience more fatigue and daytime sleep

Some people feel worse than others after a stroke. Stroke patients with cognitive and emotional problems tend to experience fatigue more often and sleep more during the day, according to recent research.

23 Feb 2024

Researchers identify potential treatment for cardiovascular disease linked to Type 2 diabetes

New research at the Roy Blunt NextGen Precision Health building has discovered a potential treatment for an underlying cause of cardiovascular disease in people with Type 2 diabetes.

23 Feb 2024

Major discovery improves the understanding of brain fog associated with Long COVID

Today, a team of scientists from Trinity College Dublin and investigators from FutureNeuro announced a major discovery that has profound importance for our understanding of brain fog and cognitive decline seen in some patients with Long COVID.

22 Feb 2024

Intravascular imaging improves survival in heart disease patients undergoing stent placement

Using intravascular imaging to guide stent implantation during percutaneous coronary intervention (PCI) in heart disease patients significantly improves survival and reduces adverse cardiovascular events compared to angiography-guided PCI alone, the most commonly used method.

22 Feb 2024

Beetroot juice outperforms nitrate supplements in boosting exercise performance

Beetroot juice (BRJ) offers superior exercise and recovery benefits compared to dietary nitrate and nitrate salts due to its rich phytonutrient content, enhancing aerobic performance and reducing fatigue.

21 Feb 2024

Study links ultra-processed food consumption with higher cardiovascular risk

Systematic review and meta-analysis revealed a linear relationship between the consumption of ultra-processed foods and an increased risk of cardiovascular events, emphasizing the need for public health initiatives to mitigate this risk.

21 Feb 2024

Mediterranean diet hailed for heart health benefits in women, study finds

Study highlights the Mediterranean diet's cardioprotective benefits for females, emphasizing its role in improving lipid profiles, blood pressure, and reducing cardiovascular disease risks, with a call for more female-focused research.

21 Feb 2024

Novel genetic locations associated with primary open-angle glaucoma identified

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma (POAG), the most common type of glaucoma and the leading cause of irreversible blindness globally.

20 Feb 2024

Mapping the genomic landscape of Type 2 diabetes

In the largest genome-wide association study to date on Type 2 diabetes, a team of international researchers, co-led by a University of Massachusetts Amherst genetic epidemiologist, has located 1,289 genetic markers associated with Type 2 diabetes (145 of which are newly identified) and generated risk scores for diabetes complications.

19 Feb 2024

Study discovers link between a breakdown product from excess niacin and heart disease

Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.

19 Feb 2024

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Researchers utilized an untargeted metabolomics technique to look for new compounds and pathways that may contribute to residual cardiovascular disease risk.

19 Feb 2024

Vascular News and Research

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

Spirulina shows promise in battling heart disease and diabetes

Researchers uncover crucial role of collateral blood vessels in stroke recovery

Study reveals how long COVID can affect brain function through vascular disruption

Reevaluating the role of direct oral anticoagulants in cardiovascular treatment

Understanding the role played by HIV in pulmonary hypertension

Some stroke patients experience more fatigue and daytime sleep

Researchers identify potential treatment for cardiovascular disease linked to Type 2 diabetes

Major discovery improves the understanding of brain fog associated with Long COVID

Intravascular imaging improves survival in heart disease patients undergoing stent placement

Beetroot juice outperforms nitrate supplements in boosting exercise performance

Study links ultra-processed food consumption with higher cardiovascular risk

Mediterranean diet hailed for heart health benefits in women, study finds

Novel genetic locations associated with primary open-angle glaucoma identified

Mapping the genomic landscape of Type 2 diabetes

Study discovers link between a breakdown product from excess niacin and heart disease

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Study uncovers key genes and cell types that may affect pathogenesis of primary open-angle glaucoma

Heart attack survivors face higher risk of long-term health conditions

MIT researchers develop new test for ventricular assist device suitability

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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