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Public reporting states have low angioplasty rates

US states in which public reporting of percutaneous coronary intervention rates by catheterization laboratories is required may have a reduced rate of the procedure in acute myocardial infarction patients, research suggests.

11 Oct 2012

Tissue test detects oral cancer risk

A molecular diagnostic scoring system based on patients’ FOXM1-associated gene messenger RNA expression levels is able to quantitatively diagnose and stratify oral carcinoma and its aggressiveness, show UK and Norwegian study results.

11 Oct 2012

Grand Challenges Canada funds 15 new projects to improve mental health diagnosis and care

Grand Challenges Canada, which is funded by the Government of Canada, today announced a landmark $19.4 million in support of 15 innovative, pioneering projects designed to improve mental health diagnosis and care in developing countries, many of them nations ravaged by conflict and disaster as well as poverty.

11 Oct 2012

Study finds reporting heart procedure results can limit use

The research in the Journal of the American Medical Association shows that in states that report outcomes from procedures to open blocked arteries, patients are less likely to get the treatment. However, they found no differences in patient survival.

11 Oct 2012

Exercise can help slow down premature cardiovascular aging effects of type 2 diabetes

One of life's certainties is that everyone ages. However, it's also certain that not everyone ages at the same rate. According to recent research being presented this week, the cardiovascular system of people with type 2 diabetes shows signs of aging significantly earlier than those without the disease.

11 Oct 2012

Preoperative comorbidity indices predictive in bladder cancer

For patients with urothelial carcinoma of the bladder who are undergoing radical cystectomy, the measurement of preoperative comorbidity indices can improve prognostication in terms of cancer-independent mortality, study results show.

10 Oct 2012

Nicotine dependence linked to symptom severity in schizophrenia

Nicotine dependence is associated with increased symptom severity in patients with schizophrenia, UK study results show.

10 Oct 2012

First Edition: October 10, 2012

Today's headlines include reports that GOP presidential candidate Mitt Romney has pledged that his presidential agenda does not include abortion legislation.

10 Oct 2012

People with diabetic foot ulcers more likely to die prematurely

People with diabetes who develop foot ulcers are at more risk of dying prematurely than those without the complication, finds a new large-scale study. The researchers say the findings highlight the potential need for improved detection and management of those with diabetes and foot ulcers.

10 Oct 2012

Proneurotensin associated with diabetes, cardiometabolic disease and breast cancer

Plasma levels of proneurotensin are associated with the development of diabetes, cardiovascular disease, cardiovascular and total mortality, and breast cancer in women during long-term follow-up, according to a study in the October 10 issue of JAMA.

10 Oct 2012

Boston Scientific initiates enrollment in Lotus Valve System clinical trial for aortic valve disease

Boston Scientific has enrolled the first patient in the REPRISE II clinical trial to evaluate the safety and performance of the Lotus Valve System in up to 120 patients with severe aortic valve disease.

10 Oct 2012

RMND1 gene mutations responsible for severe neurodegenerative disorders

Scientists at the Montreal Neurological Institute and Hospital - The Neuro, McGill University working with a team at Oxford University have uncovered the genetic defect underlying a group of rare genetic disorders.

10 Oct 2012

Aspirin associated with reduced risk of serious ovarian cancer

New research shows that women who regularly use pain relief medications, particularly aspirin, have a decreased risk of serious ovarian cancer—an aggressive carcinoma affecting the surface of the ovary.

10 Oct 2012

Transfused blood age does not impact outcomes in premature babies

Using fresh red blood cells for premature babies who need blood transfusions does not improve outcomes over use of standard blood bank donations, show study findings published in JAMA.

9 Oct 2012

Physical activity fights cognitive dysfunction after stroke

A program of aerobic and resistance training helps patients overcome cognitive deficits occurring as a result of stroke, shows research presented at the 3rd Canadian Stroke Congress in Calgary, Alberta.

9 Oct 2012

Early communication strategies improve end of liver transplant patients’ lives

A multidisciplinary communication intervention involving physicians and family members of liver transplant patients treated in surgical intensive care units can improve end-of-life care, show study results.

9 Oct 2012

Isolated fetal echogenic bowel ‘may be benign’

Results of a Dutch study show that the majority of fetuses with fetal echogenic bowel carry a good prognosis.

9 Oct 2012

ARIPI trial: Fresh blood not better for acutely ill premature babies

In a finding that runs counter to commonly held beliefs about fresh being better, a clinical trial published today by the Journal of the American Medical Association shows that acutely ill premature babies who received fresher blood did not fare better than those who received the current standard of care. There was no difference between the two approaches with respect to major organ injury, mortality and infection.

9 Oct 2012

Study examines trends in HIV mortality

Overall death rates due to human immunodeficiency virus (HIV) infection declined over time between 1993 and 2007 for most men and women by race/ethnicity and educational levels, with the largest absolute decreases for nonwhites, but rates remain high among blacks, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication.

9 Oct 2012

Wait until infection is confirmed before starting antimicrobials in ICU

Delaying antimicrobial treatment of patients in the surgical intensive care unit who have a suspected hospital-acquired infection does not increase the risk for mortality, and may even be associated with better outcomes than starting antimicrobials before culturing blood, say researchers.

8 Oct 2012