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Researchers trigger E. coli’s toxin-antitoxin system to inhibit bacterial growth

According to new research, the toxin-antitoxin (TA) system found within E. coli can be induced to inhibit the growth of the bacterium. This may have important consequences for human infection.

23 Apr 2018

Researchers identify target gene in P. aeruginosa infection

Researchers have discovered a gene linked to fatal outcomes in Pseudomonas aeruginosa (P. aeruginosa) infection that could be used as a novel prognostic biomarker and treatment target.

23 Apr 2018

Salamander study provides clues for treating spinal cord injuries

One of the most vexing problems with spinal cord injuries is that the human body does not rebuild nerves once they have been damaged. Other animals, on the other hand, seem to have no problem repairing broken neurons.

23 Apr 2018

New studies related to causes of liver degradation and possible treatments

A treatment gap remains for many conditions involving damage to the liver, the body's main organ for removing toxins, among other functions. The Experimental Biology 2018 meeting (EB 2018) will feature important research announcements related to the causes of liver degradation and possible treatments.

23 Apr 2018

Scientists illustrate role of novel chromosomal mutations in fosfomycin resistance

Researchers identified novel chromosomal mutations and described their role in the development of resistance of Escherichia coli (E. coli) to broad-spectrum antibiotic fosfomycin, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases.

23 Apr 2018

Study examines how higher-order gene combinations help maintain normal cell physiology

We inherit many traits from our parents including the color of our eyes and hair. Unfortunately, we also inherit risk factors for certain diseases such as cancer, heart disease, and diabetes. Understanding those genetic connections can help prevention efforts and develop new life-saving treatments to combat these diseases.

20 Apr 2018

CPRIT awards $2 million grant to push forward breast cancer research in West Texas

A $2 million grant from the Cancer Prevention and Research Institute of Texas will allow Texas Tech University Health Sciences Center El Paso to create a new lab focusing on breast cancer, pushing forward breast cancer research in West Texas.

20 Apr 2018

Scientists identify gene responsible for evolution of recombination rates

Genetics is a crapshoot. During sexual reproduction, genes from both the mother and the father mix and mingle to produce a genetic combination unique to each offspring. In most cases, the chromosomes line up properly and crossover. In some unlucky cases, however, "selfish DNA" enters the mix, causing abnormal crossovers with deletions or insertions in chromosomes, which can manifest as birth defects.

20 Apr 2018

Unhealthy diet damages the development of immature fat cells, study shows

24 hours. This is all it takes for a so-called precursor fat cell to have its 'epigenetic recipe' on how to correctly develop into a mature fat cell, reprogrammed.

20 Apr 2018

Drawbacks and benefits of using saliva for epigenetic studies

Biomarkers in saliva identify changes that impact the body, according to research published in Current Genomics. This important paper details the drawbacks and benefits of using saliva as a tissue sample for the study of epigenetic changes affected by experiences.

20 Apr 2018

Study may explain how chemoresistance evolves over time in some triple-negative breast cancers

Triple-negative breast cancer is an aggressive form of the disease accounting for 12 to 18 percent of breast cancers. It is a scary diagnosis, and even though chemotherapy can be effective as standard-of-care, many patients become resistant to treatment.

20 Apr 2018

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

20 Apr 2018

Study findings could open new possibilities for treating cancer with adenovirus

Adenovirus is a common virus that causes infectious diseases of the respiratory tract, eyes and gastrointestinal tract in humans and animals. Researchers at Umeå University study molecular mechanisms of infection in order to understand how adenovirus causes disease.

20 Apr 2018

EPFL becomes part of Chan Zuckerberg’s project to develop Human Cell Atlas

"The automated single-cell analysis pipeline is a software tool that catalyzes interdisciplinary work as it allows non-expert labs to engage in high-level genomic research that otherwise would require significant computational expertise," explains Professor Bart Deplancke, director of a lab at EPFL's Institute of Bioengineering.

20 Apr 2018

New CRISPR tool allows DNA editing outside of the cell

Researchers have developed a cell free method of gene editing, which uses a new version of the CRISPR tool that can edit DNA outside of the cell. This technique could revolutionize cancer care.

20 Apr 2018

BD introduces new informatics and automation solutions for clinical laboratories

BD (Becton, Dickinson and Company), a leading global medical technology company, today introduced several new informatics and automation solutions for clinical laboratories, which may play a critical role in the fight against infectious diseases and antimicrobial resistance.

From BD (Becton, Dickinson and Company) 20 Apr 2018

Scientists publish comprehensive lineage tree of whole adult animal in Science journal

From one stem cell to many differentiated body cells: Scientists from the MDC in Berlin, along with collaborating researchers in Munich, have published a comprehensive lineage tree of a whole adult animal in the journal Science. This was made possible by a combination of RNA and computational technologies.

20 Apr 2018

Rare variants in non-coding DNA inherited from parents heighten autism risk

In recent years, researchers have firmly established that gene mutations appearing for the first time, called de novo mutations, contribute to approximately one-third of cases of autism spectrum disorder.

20 Apr 2018

Researchers discover new information related to rare form of leukemia

International research consortium led by researchers from the University of Helsinki, Finland, discovered new information related to a rare form of leukemia called aggressive NK-cell leukemia.

20 Apr 2018

Triple-negative breast cancer found to be chemoresistant prior to treatment

Difficult to treat and aggressive "triple-negative" breast cancer is chemoresistant even before chemotherapy begins, a new study by researchers from Karolinska Institutet and the University of Texas MD Anderson Cancer Center reports. The findings, which are published in the journal Cell, may lead to better and more personalized treatments for breast cancer.

19 Apr 2018