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Oncolytic virotherapy lends benefits to melanoma patients

Recent study published online by Melanoma Research journal indicates that melanoma patients would significantly benefit from prolonging the survival with oncolytic viroherapy treatment. The study revealed that the early stage melanoma patients treated with oncolytic medicine Rigvir were 4 to 6 times more likely to survive than those who following the current guidelines for the treatment of melanoma were only observed.

19 Aug 2015

New study compares effectiveness of tinzaparin and warfarin in patients with active cancer, recurrent VTE

Among patients with active cancer and acute symptomatic venous thromboembolism (VTE; blood clots in the deep veins), the use of the low molecular-weight heparin tinzaparin daily for 6 months compared with warfarin did not significantly reduce recurrent VTE and was not associated with reductions in overall death or major bleeding, but was associated with a lower rate of clinically relevant nonmajor bleeding, according to a study in the August 18 issue of JAMA.

19 Aug 2015

Only 1 in 10 heart failure patients referred to cardiac rehabilitation program after hospitalization

Only 1 in 10 heart failure patients is referred to a cardiac rehabilitation program after being hospitalized, despite strong evidence that such exercise programs improve quality of life and reduce the likelihood of future hospitalizations.

19 Aug 2015

Loyola implants new percutaneous aortic heart valve that does not require open surgery

Loyola University Medical Center is the first center in Illinois to implant a new percutaneous aortic heart valve that does not require open heart surgery.

19 Aug 2015

Patient satisfaction a poor proxy for quality of care in elective cranial neurosurgery

Patient satisfaction is a very poor proxy for quality of care comparisons in elective cranial neurosurgery. Because deaths are rare events in elective cranial neurosurgery, reporting of surgeon or even department-specific mortality figures cannot differentiate a high or low level of the quality of care.

18 Aug 2015

HCT not precluded by prior second-generation TKI therapy in chronic, advanced phase CML

Allogeneic haematopoietic stem cell transplantation can be considered for chronic- and accelerated-phase chronic myeloid leukaemia patients with prior exposure to second-generation tyrosine kinase inhibitors, say Polish researchers.

17 Aug 2015

Staffordshire and Stoke on Trent Partnership aims to be the first NHS Trust to review all deaths

Staffordshire and Stoke on Trent Partnership NHS Trust, the UK’s biggest provider of community health and adult social care, is aiming to be the first NHS Trust in the country to review all deaths.

17 Aug 2015

LSTM's CMNH raises funds for Ebola-hit maternal health facilities in Sierra Leone

Earlier this year LSTM's Centre for Maternal and Newborn Health (CMNH) cycled 4,247 miles to raise funds for urgently needed medical equipment for maternal health facilities in Sierra Leone which have been affected by the Ebola outbreak.

17 Aug 2015

Breastfeeding may lead to substantial reduction in common infections among Indigenous babies

Promoting breastfeeding could lead to a substantial reduction in common infections and even deaths that are more common in Indigenous infants than non-Indigenous infants, a new study suggests.

17 Aug 2015

Study looks at infant mortality rates of extremely preterm infants

About 500,000 babies are born premature in the United States each year, according to the U.S. National Library of Medicine. Those infants, born before 37 weeks of gestation, will likely deal with the threat of numerous complications or even death.

15 Aug 2015

New study explores impact of climate change on human health

Researchers at Columbia University's National Center for Disaster Preparedness and the University of Washington have published a new study focused on the public health implications of climate change. The article explores climate change impacts on human health in the U.S. Gulf Coast and has implications for this and other coastal regions that are particularly vulnerable to climate change.

14 Aug 2015

HCT not precluded by prior second-generation TKI therapy in chronic, advanced phase CML

14 Aug 2015

Arterial shunt in hybrid palliation better for hypoplastic left heart syndrome treatment

Children born with the major congenital heart defect hypoplastic left heart syndrome (HLHS) often must undergo a series of corrective surgeries beginning at birth. While most have the standard three-stage Norwood procedure, a hybrid strategy has been introduced to offset some disadvantages associated with the Norwood surgeries. In a report in The Journal of Thoracic and Cardiovascular Surgery, investigators compare whether outcomes can be improved if an arterial shunt is used as a source of pulmonary blood flow rather than the more conventional venous shunt as part of the hybrid strategy of HLHS surgical reconstruction.

14 Aug 2015

Researchers use advanced photodynamic therapy to combat ovarian cancer in laboratory animals

Researchers at Oregon State University have made a significant advance in the use of photodynamic therapy to combat ovarian cancer in laboratory animals, using a combination of techniques that achieved complete cancer cell elimination with no regrowth of tumors.

14 Aug 2015

Study explores association between treatment patients receive in hospital and risk of death

A University of Manchester study which followed up 38,415 people admitted to hospital with self-harm has, for the first time, investigated the association between the treatment patients receive in hospital and their subsequent risk of death.

14 Aug 2015

ESC Congress to highlight results from global trials in six press conferences

Members of the press will be the first to hear the highly anticipated results from global trials in six press conferences devoted to hot lines research.

13 Aug 2015

Depressive symptoms, stress, anxiety and anger in RA patients linked to atherosclerosis

New research reveals that depressive symptoms, stress, anxiety, and anger and lack of social support in patients with rheumatoid arthritis (RA) were linked to atherosclerosis--a build-up of fatty deposits in the arteries that contributes to cardiovascular disease. The study published in Arthritis Care & Research, a journal of the American College of Rheumatology, suggests that screening and treatment of psychosocial symptoms may curb the cardiovascular disease burden in RA patients.

13 Aug 2015

Chances of survival due to chemotherapy significantly lower for older breast cancer patients

Chemotherapy prolongs life for older adults with most types of cancer, but for women over the age of 80 with breast cancer, the chances of survival due to chemotherapy are significantly lower, according to a study led by researchers from The University of Texas Health Science Center at Houston.

13 Aug 2015

Johns Hopkins study finds substantial increase in rate, costs of hospitalizations for pediatric pulmonary hypertension

A review of 15 years’ worth of data in a national pediatric medical database has documented a substantial increase in the rate of hospitalizations for children with a form of high blood pressure once most common in those with congenital heart disease.

13 Aug 2015

Delaying surgery until clinical triggers emerge leads to increased mortality in patients with mitral regurgitation

Patients with mitral regurgitation face a dilemma of whether to undergo corrective surgery early, when they might have no or few symptoms, or wait until their condition worsens. Current guidelines allow for watchful waiting until certain symptoms appear that would then "trigger" the decision to proceed with surgery.

12 Aug 2015

Mortality News and Research

Oncolytic virotherapy lends benefits to melanoma patients

New study compares effectiveness of tinzaparin and warfarin in patients with active cancer, recurrent VTE

Only 1 in 10 heart failure patients referred to cardiac rehabilitation program after hospitalization

Loyola implants new percutaneous aortic heart valve that does not require open surgery

Patient satisfaction a poor proxy for quality of care in elective cranial neurosurgery

HCT not precluded by prior second-generation TKI therapy in chronic, advanced phase CML

Staffordshire and Stoke on Trent Partnership aims to be the first NHS Trust to review all deaths

LSTM's CMNH raises funds for Ebola-hit maternal health facilities in Sierra Leone

Breastfeeding may lead to substantial reduction in common infections among Indigenous babies

Study looks at infant mortality rates of extremely preterm infants

New study explores impact of climate change on human health

HCT not precluded by prior second-generation TKI therapy in chronic, advanced phase CML

Arterial shunt in hybrid palliation better for hypoplastic left heart syndrome treatment

Researchers use advanced photodynamic therapy to combat ovarian cancer in laboratory animals

Study explores association between treatment patients receive in hospital and risk of death

ESC Congress to highlight results from global trials in six press conferences

Depressive symptoms, stress, anxiety and anger in RA patients linked to atherosclerosis

Chances of survival due to chemotherapy significantly lower for older breast cancer patients

Johns Hopkins study finds substantial increase in rate, costs of hospitalizations for pediatric pulmonary hypertension

Delaying surgery until clinical triggers emerge leads to increased mortality in patients with mitral regurgitation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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