Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists identify new genes associated with familial Meniere's disease

A team of scientists from the University of Granada (UGR) and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research—led by Pablo Roman-Naranjo and Jose Antonio López-Escámez, researcher in charge of the Biohealth Research Institute in Granada (ibs.GRANADA)—has identified new genes associated with familial Meniere's disease.

1 Dec 2021

Study shows long-term safety and biologic activity of golodirsen in DMD patients

This first-in-human study of golodirsen showed its long-term safety and biologic activity in patients with Duchenne Muscular Dystrophy (DMD). The approved exon-skipping therapy is designed to enable the production of functional dystrophin proteins, as described in the peer-reviewed journal Nucleic Acid Therapeutics.

1 Dec 2021

Comparison of peptides from human cardiac proteins and SARS-CoV-2 proteins

A new study investigated whether linear peptides contained in proteins (primarily expressed in the heart) also occur in the SARS-CoV-2 proteome.

1 Dec 2021

Study sheds light on Aβ deposition patterns in the brain from external sources

Alzheimer's disease (AD) involves the deposition of a protein called amyloid β protein (Aβ) in the brain. This protein can build up in both the functional tissues, or "parenchyma", of the brain, and in the blood vessels.

30 Nov 2021

Nanoengineers develop a new approach to effectively deliver mRNA into cells

Nanoengineers at the University of California San Diego have developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells.

30 Nov 2021

An antiviral regimen based on biomimetic polymers for COVID-19

In a new study published on the bioRxiv* preprint server, scientists proposed the aforementioned mechanism of action (MOA) and have validated it using electron photomicrographs of murine cytomegalovirus (MCMV), which were incubated with a nanoviricide.

30 Nov 2021

'Biosensor barcodes' can identify and track how cancer cells 'talk' to each other

Ever since the first barcode appeared on a pack of chewing gum in 1974, the now-ubiquitous system has enabled manufacturers, retailers and consumers to quickly and effectively identify, characterize, locate and track products and materials.

30 Nov 2021

New combination treatment enables complete tumor regression in mice with high-risk neuroblastoma

In mice with high-risk neuroblastoma, tumors disappeared in response to a new combination treatment with precision medicines, a recent study from University of Gothenburg researchers shows.

30 Nov 2021

Virginia Tech researchers discover potential target for diagnosing and treating Lyme disease

You don't have to go far to find ticks. Just step outside and look for some grass. Look to the top of the shiny, green blade – usually ankle high. A tick might be there, waiting.

30 Nov 2021

Omicron and other coronavirus variants: What you need to know

Americans, already weary of a pandemic nearly two years long, were dealt a new blow during the long Thanksgiving weekend: the announcement that a new coronavirus variant had emerged.

30 Nov 2021

Prior infection with SARS-CoV-2 continues to provide protection from reinfection

Researchers from the University of Michigan investigated the correlation between SARS-CoV-2 infection and the severity of reinfections.

30 Nov 2021

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers investigate potentially amyloidogenic peptide fragments that could be associated with the neurological symptoms of COVID-19 and long-COVID.

30 Nov 2021

Host and in vitro genomic variability of SARS-CoV-2 and its variants

Researchers from the University of Sydney investigate the genomic variability of SARS-CoV-2 within the host and in vitro.

30 Nov 2021

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Anti-SARS-CoV-2 antibodies suggested to be safe to use in pregnancy

Pregnant patients with mild to moderate COVID-19 were treated with MAb and reported no adverse effects.

30 Nov 2021

Study uncovers new mechanism to explain how obesity jeopardizes the functions of skeletal muscle

A decline in metabolism and endurance of skeletal muscle is commonly observed in obese patients, but the underlying mechanism is not well-understood.

30 Nov 2021

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.

29 Nov 2021

SARS-CoV-2 Delta spike increases viral virulence and inflammatory cytokine production

In a new study published on the bioRxiv* preprint server, scientists investigated several virological features of the Delta spike protein.

29 Nov 2021

Targeted measures to prevent the spread of Omicron variant take effect from 30 November 2021

Targeted measures to prevent the spread of the new COVID-19 Omicron variant take effect from 4am today [Tuesday 30 November].

29 Nov 2021

New phenotype of LRP6 mutation reported for the first time in patients with tooth agenesis

A group led by Prof. Han Dong of Peking University School of Stomatology reported for the first time hand preaxial polydactyly in patients with tooth agenesis carrying a previously unknown mutation of low-density lipoprotein receptor-related protein 6 (LRP6).

29 Nov 2021

Protein News and Research

Further Reading

Scientists identify new genes associated with familial Meniere's disease

Study shows long-term safety and biologic activity of golodirsen in DMD patients

Comparison of peptides from human cardiac proteins and SARS-CoV-2 proteins

Study sheds light on Aβ deposition patterns in the brain from external sources

Nanoengineers develop a new approach to effectively deliver mRNA into cells

An antiviral regimen based on biomimetic polymers for COVID-19

'Biosensor barcodes' can identify and track how cancer cells 'talk' to each other

New combination treatment enables complete tumor regression in mice with high-risk neuroblastoma

Virginia Tech researchers discover potential target for diagnosing and treating Lyme disease

Omicron and other coronavirus variants: What you need to know

Prior infection with SARS-CoV-2 continues to provide protection from reinfection

Potentially neurotoxic SARS-CoV-2 protein fragments

Host and in vitro genomic variability of SARS-CoV-2 and its variants

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

Anti-SARS-CoV-2 antibodies suggested to be safe to use in pregnancy

Study uncovers new mechanism to explain how obesity jeopardizes the functions of skeletal muscle

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

SARS-CoV-2 Delta spike increases viral virulence and inflammatory cytokine production

Targeted measures to prevent the spread of Omicron variant take effect from 30 November 2021

New phenotype of LRP6 mutation reported for the first time in patients with tooth agenesis

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