Angiotensin News and Research

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Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.

Cholesterol-lowering drugs not helpful in reducing COVID-related mortality or severity

In the worldwide effort to battle SARS-CoV-2, the virus that causes COVID-19, researchers have often turned to medications used as therapies for other conditions in the hopes of finding ones that either kill the coronavirus or lessen the impacts from its infection.

26 Oct 2021

A high-throughput pipeline for identifying nanobodies that target and neutralize SARS-CoV-2

Researchers in the United States have developed a cost-effective, high-throughput pipeline for identifying effective nanobodies that target and neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

26 Oct 2021

Study finds SARS-CoV-2 infection is proportional to cell surface ACE2 levels

Researchers from Oregon State University have developed a system to assess the ability of SARS-CoV-2 to bind to ACE2 orthologs.

26 Oct 2021

Regulating blood insulin levels in obese, diabetic patients may help reduce COVID-19 risk

Keeping blood insulin levels within strict, healthy parameters is a daily goal for people with diabetes. But now, researchers from Japan have found that regulating blood insulin levels may even help lower the risk of getting COVID-19.

25 Oct 2021

Are non-human primates at risk of SARS-CoV-2 exposure through wastewater contact?

Researchers have been investigating the potential for SARS-CoV-2 to spread to NHP through wastewater.

25 Oct 2021

Molecular features of SARS-CoV-2 variant receptor binding

Researchers have been investigating the changes in receptor binding in these variants that increase the danger they pose.

25 Oct 2021

Blood pressure drug increases SARS-CoV-2 receptors in transmission and pathogenesis associated tissues

A new study aimed to determine whether ACE2 targeting drugs change the tissue levels of ACE2 in healthy mice.

25 Oct 2021

Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

Researchers isolated single cells among individuals with and without prior infection with the SARS-CoV-2 vaccinated with BNT162b2 mRNA vaccine and compared the nature of the neutralizing antibody response against the original Wuhan virus and the subsequent variants.

25 Oct 2021

Targeting SARS-CoV-2 with Chaga mushroom – a natural antiviral compound

A new study examines the potential binding interaction of the beneficial components of Chaga mushroom with that of the SARS-CoV-2 RBD.

24 Oct 2021

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Researchers discuss mutations in the NTD of the spike protein, which contains an antigenic “supersite” and is the target for nAbs.

24 Oct 2021

Development of a safe and effective COVID-19 nanoparticle vaccine

Researchers from ReVacc scientific have attempted to demonstrate the effectiveness of a new vaccine, REVC-128, two weeks post-administration.

22 Oct 2021

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Researchers from Stanford University have been attempting to create a hydrogel-based vaccine delivery system that could improve the immune response's strength and duration.

22 Oct 2021

Development of a plant-based platform for the production of SARS-CoV-2 antigen

Scientists have recently focused on the development of plant-based recombinant protein platforms.

21 Oct 2021

New research on phagocytosis and SARS-CoV-2's spike protein

A new study showed that convalescent patient plasma and monoclonal anti-spike antibodies were able to induce phagocytosis at high antibody concentrations.

20 Oct 2021

Biomarker predicts severity of SARS-CoV-2 infection in patients

A new study investigates a biomarker to predict the severity of disease in patients infected with SARS-CoV-2.

20 Oct 2021

The neutralization potential of nanobodies against SARS-CoV-2

A recent review describes the role of nanobodies as a new class of recombinant antibodies that are used in the treatment of COVID-19.

20 Oct 2021

Suggested mechanism of SARS-CoV-2 infection inhibition by Mitoxantrone

A group of researchers performed a drug repurposing screen on an FDA-approved anti-cancer drug named Mitoxantrone.

20 Oct 2021

Long-term predictions of immunity after two doses of mRNA vaccine

Researchers from York University has investigated the long-term protection of two mRNA vaccines.

20 Oct 2021

BNT162b2 mRNA COVID-19 vaccine-induced antibodies wane over six month period

Researchers have been investigating the response of antibodies created against SARS-CoV-2 by the Pfizer-BioNTech six months after vaccination.

20 Oct 2021

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

In a recent study published in the journal PLOS Pathogens, scientists showed that nasal administration of a single-domain antibody (VHH), named K-874A, brought about inhibition of SARS-CoV-2 titers in infected lungs of Syrian hamsters.

19 Oct 2021

Angiotensin News and Research

Further Reading

Cholesterol-lowering drugs not helpful in reducing COVID-related mortality or severity

A high-throughput pipeline for identifying nanobodies that target and neutralize SARS-CoV-2

Study finds SARS-CoV-2 infection is proportional to cell surface ACE2 levels

Regulating blood insulin levels in obese, diabetic patients may help reduce COVID-19 risk

Are non-human primates at risk of SARS-CoV-2 exposure through wastewater contact?

Molecular features of SARS-CoV-2 variant receptor binding

Blood pressure drug increases SARS-CoV-2 receptors in transmission and pathogenesis associated tissues

Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

Targeting SARS-CoV-2 with Chaga mushroom – a natural antiviral compound

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Development of a safe and effective COVID-19 nanoparticle vaccine

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Development of a plant-based platform for the production of SARS-CoV-2 antigen

New research on phagocytosis and SARS-CoV-2's spike protein

Biomarker predicts severity of SARS-CoV-2 infection in patients

The neutralization potential of nanobodies against SARS-CoV-2

Suggested mechanism of SARS-CoV-2 infection inhibition by Mitoxantrone

Long-term predictions of immunity after two doses of mRNA vaccine

BNT162b2 mRNA COVID-19 vaccine-induced antibodies wane over six month period

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

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Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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